DRUG STUDY

sName Indication Contraindication Interaction Adverse Nursing

Effect Consideration

CEFUROXIME Management of UTI’s due to Hypersensitivity to Furosemide increased renal toxicity Diarrhea Infuse
e.coli or klebsiella. cephlosphorines and other Antacids decreased plasma levels. Rush cefuroxime for
Classification: antibiotics. Nausea 30 minutes.
Cephalosporin ACTION: Treatment of susceptible Pain in the Monitor vital
Antibiotics. Cephalosphorins interfere eith protozoal infections injection site signs.
final in the formation of the eg amoebiasis,
Dosage: bacterial cell wall, resulting in balantidiasis, Blastocystis
750 mg/ IV every 8 unstable cell membranes that hominis infections, giardiasis 
hours undergo lysis. & trichomoniasis.

CIPROFROXACIN Bone and Joint Hypersensitivity. Not to be Decreased absorption with Headache History:
 
Infections caused used concurrently with concurrent sucralfate, magnesium- Nausea Allergy to
Classification: by Enterobacter cloacae, Vomiting
Antibiotic Serratia
tizanidine. Avoid exposure to aluminum
Diarrhea
ciprofloxacin, 
Flouroquinolone marcescens, orPseudomonas strong sunlight or sun lamps antacids, calcium, iron, zinc and Restlessness norfloxacin or
aeruginosa. during treatment. multivitamins. Rash other
Dosage: Increased methotrexate and caffeine  quinolones;
200 mg/ IV every 8 ACTION: levels when taken concurrently with renal
hours Ciprofloxacin inhibits an ciprofloxacin.
enzyme called DNA gyrase
dysfunction;
that is an essential component seizures;
of the mechanism that passes lactation
genetic information onto Physical: Skin
daighter cells when a cell color, lesions;
divides.
T; orientation,
reflexes,
affect; mucous
membranes,
bowel sounds;
renal and liver
function tests

METRONIDAZOLE Treatment of susceptible Blood dyscrasias, active Alcohol may cause disulfiram-like Head ache Monitor vital
protozoal infections organic disease of the CNS, reaction. Potentiates anticoagulant Vaginitis signs.
Classification eg amoebiasis, trichomoniasis during the effect of warfarin-type oral Nausea Don’t give IV
Antibiotic first trimester of pregnancy, anticoagulants. Plasma levels Metallic taste bolus.
balantidiasis, Blastocystis
lacrtation. of lithium may be increased. Genital Discontinue
Dosage: hominis infections, giardiasis  Phenobarb increases the metabolism Pruritis primary IV
& trichomoniasis. of metronidazole. Bacterial infusion during
Infection infusion of this
 DRUG STUDY
500 mg every 8 hours ACTION: Flu-like drug.
through IV Effective against anaerobic symptoms
bacteria and protozoa.
Specifically inhibits growth of
trichomonae and amoebae by
binding to DNA , resulting in
lost of helical structure, strand
breakage, inhibition acid
synthesis and cell death.