Angeles University Foundation

Angeles City

College of Nursing

Drug Study
In Partial Fulfillment of the Requirements
In Related Learning Experience 102

Submitted by:

Lim, Raymond Christopher P.

BSN II-6/ Group 23

Submitted to:

Mr. Rolly M. Policarpio RN

Clinical Instructor

January 27, 2011

A.Y. 2010-2011
Ampalaya (Mamordica Charantia)

Amargoso (Sp.); Pubia (Sub.); Suligum (Sul.);

Margoso, Ampalaya (Tag.);

Apalia (Pamp.); Apape (Ibn.);

Apapet (Itn.); Palia (Bis., Ban., Lf., Ilk.);

Balsam Apple, Balsam Pear, Bitter Gourd (Eng.)

Use:

Lower blood sugar levels

Diabetes Mellitus (Mild non-insulin dependent)

Preparation:

Gather and wash young leaves very well. Chop. Boil 6 tablespoons in two
glassfuls of water for 15 minutes under low fire. Do not cover pot. Cool and strain. Take
1/3 cup three times a day after meals.

Note:

Young leaves may be blanched/steamed and eaten ½ glassful 2 times a day.

Meclizine Hydrochloride

Brand Name: Bonamine, Bonine, Dramine Less Drowsy Formula

Drug Class: Anticholinergic, Antiemetic, Antihistamine, Anti-motion sickness drug

Therapeutic Actions:

Reduces sensitivity of the labyrinth apparatus, probably acts at least partly by blocking
cholinergic synapses in the vomiting center, which receives input from the CTZ and
from peripheral nerve pathways, peripheral anticholinergic effects may contribute to
efficacy.

Indications:

• Prevention and treatment of nausea, vomiting and motion sickness

• Possibly effective for the treatment of vertigo associated with diseases affecting
the vestibular system.

Contraindications and Cautions:

• Contraindicated with allergy to meclizine or cyclizine; tartrazine sensitivity

• Use cautiously with lactation, narrowed-angle glaucoma, stenosing peptic ulcer,

symptomatic prostatic hypertrophy, bronchial asthma, bladder neck obstruction,
cardiac arrhythmias, postoperative state, and pregnancy.

Available Forms:

Tablets- 12.5, 25, 50 mg

Chewable tablets- 25 mg
Capsules- 25 mg

Dosages:

Adults

• Motion sickness: 25-50 mg PO 1 hr before travel. May repeat dose every 24 hr

for the duration of the journey.

• Vertigo: 25-100 mg PO daily in divided doses

Pediatric Patients

Not recommended for children younger than 12 yr

Geriatric Patients

Most likely to cause dizziness, sedation, syncope, toxic confusional states and
hypotension in elderly patients, use with caution.

Pharmacokinetics

Route Onset Peak Duration

Oral 1 hr 1-2 hr 4-24 hr

Metabolism: T ½ :6 hr

Distribution: Crosses placenta, may enter breast milk

Excretion: Feces

Adverse Effects

CNS: drowsiness, confusion,

CV: hypotension, palpitations, tachycardia

GI: dry mouth, anorexia, nausea, vomiting, diarrhea or constipation

GU: urinary frequency, difficult urination

Respiratory: respiratory depression, death

Interactions:

Increased sedation with alcohol or other CNS depressants

Nursing Considerations:

• Assess for history of allergy to meclizine or cyclizine, pregnancy, narrowed-angle

glaucoma, stenosing peptic ulcer, symptomatic prostatic hypertrophy, bronchial
asthma, bladder neck obstruction, pyloroduodenal obstruction, cardiac
arrhythmias, postoperative state, lactation, pregnancy.

• Monitor I & O, and take appropriate measures with urine retention.

• Advise patient to take the drug as prescribed.

• Inform the patient that anti-motion sickness drugs work best if used ahead of time
for prevention.

• Advise the patient to avoid alcohol as serious sedation could occur.

• Inform the patient of the side effects.

• Advise the patient to report difficulty of breathing, hallucinations, tremors, loss of

coordination, visual disturbances and irregular heartbeat.