1.

Transmission of genetic information bewixt cells with the help of bacteriophage is called
a) Transduction x
b) Transformation
c) Conjugation
d) Translation

2. Tetracyclin is an antibioticum of choice for infections

a) in children
b) zoonosis caused by intracellular bacteria
c) with bacteriocidic activity x
d) caused by parasites

3. Lysogenic bacterium
a) carries a prophage x
b) causes lysis of other bacteria
c) can't support the replication of virulent phage
d) is a human pathogen

4. Which of mentioned is used to treat bladder infections caused by G-negative rods (E.Coli)
a) penicilin
b) sulfonamides x
c) izoniazid
d) oxacilin

5. The forst antistaphylococcal penicilin antibioticum – still efficient in most of staphylococcus

aureus in Slovakia – with emerging resistance that can be cause of severe hospital infection problem
is
a) methicilin x
b) penicilin
c) erytomycin
d) tetracyclin

6. Which of the following contains peptidoglycans

a) ribosomes
b) gram-positive cell walls only
c) flagella and all bacterial cell walls
d) gram-negative cell wall and b) x

7. Encapsulated bacteria
a) are sometimes more virulent than their non encapsulated counterparts x
b) are more susceptible to phagocytic destruction
c) are easier to swallow than tablet bacteria
d) are more resistant than viruses

8. Exotoxin of Clostridium Tetani is the tool of

a) virulence
b) pathogenicity
c) infection
d) immunity x

9. Transformation as a process of transmission of free genetic information was described by

a) Griffith, during study of encapsulated and nonencapsulated strains of Streptococcus
Pneumoniae x
b) Lancefield during the study of cell wall antigens of streptococci
c) Bergey during preparation of the system of bacteria
d) Loowenhoed when studying microbes in the microscope he produced

10. Penicilin antibiotics are not toxic to human because

a) they are produced by eatable fungi
b) they have a simple structure
c) they do not cross the intestine barrier
d) they are efficient on the level of cell wall structures x

11. Spherical bacteria arranged in a chain are known as

a) spiromhmhm
b) staphylococci
c) streptococci x
d) streptobacilli

12. A microorganism that is commensal

a) does not recieve any benefit from its host
b) is harmful to its host
c) receives benefit from its host x
d) none of the above describe a commensal bacteria

13. Which of mentioned inactivates beta lactamases

a) penicilin
b) clavulanic acid x
c) ampicilin
d) cephalosporins

14. Target structure of penicilin antibiotics is not present on animal cells because it is part of
a) cell wall x
b) plasmatic membrane
c) mictochondria
d) nucleic acids

15. Cell membranes are composed primarily of

a) protein and polysaccharides
b) peptidoglycan in prokaryotes
c) protein and phospholipid x
d) phospholipd and polysaccharides

16. The segments of DNA transferred bewixt cells are

a) large
b) small
c) circular x
d) not functional

17. The site of protein synthesis in prokaryotic cells

a) are in the mitochondria
b) is the LPS
c) is the cell membrane
d) are the ribosomes x
 18. Conjugation is the transmission of genetic information via
a) flagella
b) pillus x
c) contact of plasmatic membrane
d) contact of VAP (Virus Attachment Protein)

19. Which of the following structures is unique to prokaryotic organisms

a) mitochondria
b) cell membrane
c) peptidoglycan cell wall x
d) ribosomes

20. Physiological flora of skin is

a) Candida Albicans and Streptococcus Pneumoniae
b) Viridant cocci and Corynebacterium Diphteriae
c) Staphylococcus Epidermis, Proponibacter Acnes x
d) no answer is correct

21. Protective against intrauterine infections are antibodies type

a) IgG
b) IgM
c) IgE
d) IgA x

22. Antitoxin is x
a) antibody against toxin
b) immunogenicity deprived toxin
c) toxicity deprived toxin
d) the same as toxoid

23. Beta-lactames are antibiotics that are efficient at the level of

a) synthesis of cell wall x
b) synthesis of nucleic acid
c) proteosynthesis
d) metabolism of folic acid

24. Infectious disease have essentially been eliminated by antibiotics and vaccination and
are no longer a public health problem. This statement is
a) true
b) false x
c) is true for Europe
d) is true for your country

25. Leewenhock's discoveries were significant because

a) he was the first scientist in the world
b) he used microscope and carefully recorded and reported his results
c) he used lenses to visualize bacteria x
d) he was the first microbiologist

26. Penicilin antobioticum with increased efficiency to gram-negative bacteria is

a) oxacilin
 b) meticilin
c) ampicilin x
d) oxolin acid

27. What type of antibodies are protective and important to eliminate a bacterium in
encapsulated strains
a) opsonising antibodies
b) antitoxic antibodies x
c) neutralizing antibodies
d) immunocomplexes

28. Translation is also known as

a) DNA synthesis
b) protein hydrolysis
c) reverse transcription
d) protein synthesis x

29. Resistance to many antibiotics is transferred by genetic information present in

a) sex pilli
b) plasmids x
c) fimbriae
d) enzymes

30. The metabolites that activate gene transcription are called

a) synthesizers
b) operators
c) inducers
d) promoters x

31. Endotoxin
a) is extremely immunogenic
b) stimulate production of precipitating antibodies
c) is a part of gram-negative cell wall x
d) is a part of gram-negative plasma membrane

32. When bacteria develop resistance to an antibiotic, the antibiotic does not caise the
mutation but only selects for a preexisting mutation (wat?)
a) true x
b) false

33. Virulence of the bacterium with Lethal Dose (LD) 50 = 1000

a) is lower than virulence of a microbe with LD = 100000
b) is higher than virulence of a microbe with LD = 100000 x
c) can't be guessed from this
d) means that this dose will kill 50 bacteria of 1000 exposed

34. Which of mentioned can cause aplastic anemia

a) chloramphenicol x
b) penicilin
c) clavulanic acid
d) chinolones
 35. The cell wall of gram-positive bacteria is composed of
a) cellulose
b) starch
c) peptidoglycan x
d) chitin

36. Lipopolysaccharide og gram-negative bacteria activates complement by

a) alternative way
b) classical way x
c) lectin way
d) only in presence of opsonising antibodies

37. The group of bacteria that do not have cell walls are
a) archaebacteria
b) mycoplasma x
c) eubacteria
d) mycobacteria

38. Cells that do not have a membrane separating their nuclear material from their cytoplasm
are called
a) heterozygotes
b) prokaryotic x
c) eukaryotic
d) viruses

39. Ability to produce disease in infected human is called

a) pathogenicity
b) virulence x
c) resistance
d) infectiousity

40. Endotoxins belong to a class of biological molecules called

a) mucopolysaccharides
b) lipopolysaccharides x
c) nucleic acids
d) proteins