Ge#ng

 Started  

Dr.  Sonya  Doherty,  ND  

Defeat  Au2sm  Now!  Prac22oner  
www.treatau2sm.ca  
www.treatadhd.ca  
Where  do  you  start?  
Ge#ng  Started  
•  Individualized  assessment  and  ongoing  tes2ng  
•  100%  commitment  to  diet  
•  Help  from  your  health  care  prac22oners  
•  Parents  on  the  same  page  
•  Caring  for  the  caregiver  
In  or  out  
•  Yeast  
•  Clostridia  
•  Streptococcus  
•  Imbalanced  microbiome  and  leaky  gut  
•  Mitochondrial  defects  
•  Detoxifica2on  impairment  
•  Methyla2on  impairment  
•  Immune  dysfunc2on  
Tes5ng  

•  OAT  –  Comprehensive  Organic  Acid  

•  Comprehensive  Diges2ve  Stool  Analysis  
•  Yeast  Stool  Profile  
•  Heavy  Metal  Tes2ng  –  hair,  stool,  urine  
Test  Overview  
•  Comprehensive  Organic  Acid  Test  
•  72  different  tests  to  help  iden2fy:  
•  Yeast  and  bacterial  overgrowth  
•  Clostridia  marker  
•  Detoxifica2on  
•  B  vitamins  and  other  key  nutrients  
•  Mitochondrial  func2on  
•  NeurotransmiTers  
•  Inflamma2on  and  toxic  exposures  
Test  Overview  
•  Comprehensive  Diges2ve  Stool  Analysis  
•  Clostridia  
•  Yeast  
•  Parasites  
•  Gut  Inflamma2on  
•  Sensi2vity  
Test  Overview  
•  Yeast  Stool  Sensi2vity  Test  
•  48  different  species  
•  Sensi2vity  
Test  Overview  
•  Speciality  Laboratories  include:  

•  Great  Plains  
•  Metametrix  
•  Doctors  Data  
Tes5ng  
•  Liver  Enzymes  
•  Cholesterol  and  Lipids  
•  Vitamin  A  and  Vitamin  D  
•  Strep  Titers  
•  Metabolic  Profile  
•  Iron  
•  Zinc  and  Copper  
Diges5on  
•  Diet  –  BDI  
•  Essen2al  FaTy  Acids  
•  Fibre  
•  Probio2cs  
•  Castor  Oil  Massage  
•  Repair  the  MICROBIOME  
Diet  
•  GFCF  
•  SCD  
•  BED  
•  Low  oxalate  
•  Feingold  
•  Candida  
•  No  sugar  
•  Removal  of  individual  food  allergies  
Yeast  

•  Botanicals  –hydras2s,  caprylic  acid,  grapefruit  

seed  extract,  berberine,  uva  ursi,  oregano  
•  Pharmaceu2cal  
•  Probio2cs  –  S.  Boulardi,  L.  Salivarius,  L.  GG  
•  Bentonite  or  Ac2vated  Charcoal  
•  Kill,  Bind,  Remove  -­‐  REPEAT  
Gut  issues  =  NT  problems  

•  Glutamate  is  converted  to  GABA  –  B6  

•  Gut  issues  impair  conversion  causing  
“hyperexcitability”  
•  YEAST  BINDS  B6  

•  Self  s2mula2ng  behaviour  

•  Hyperac2vity  
•  Difficulty  learning,  processing  and  focusing  
•  Impulsivity  
•  Impaired  development  
Clostridia  Protocol  

•  Methyla2on  impairment  –  B12  &  MTHF  

•  Deple2on  of  carni2ne  –  EFAs  &  carni2ne  
•  Deple2on  of  glutathione  –  NAC,  selenium  
•  Mitochondrial  stressor  –  CoQ10,  ALA  
•  Clostridia  in  gut  –  Culturelle  and  S.Boulardi  
Microbiome  Repair  

•  Evidence  shows  that  modern  humans  evolved  

in  Africa  200,  000  years  ago  

•  It  took  200,  000  years  to  perfect  your  

individual  microbiome  

•  Imbalance  C-­‐sec2ons,  an2bio2cs,  diet  

Miracle  Drug  

•  Would  you  treat  your  child  with  a  drug  that  

could:  
•  Decrease  inflamma2on  
•  Regulate  immunity  –  protect  against  autoimmunity  
•  Protect  against  infec2on  –  Clostridia,  Yeast,  Strep  
•  Detoxify  metals  and  harmful  chemicals  
•  Absorb  and  synthesize  nutrients  -­‐  essen2al  faTy  acids  and  zinc  
•  Decrease  inflamma2on  
•  Increase  energy  
•  Increase  serotonin  by  95%  
•  Increase  neurotransmiTer  produc2on  –  dopamine  
Your  child’s  miracle  drug  
B.  bifidum  lac5s  

•  Prominent  microorganism  in  the  mucous  membrane  lining  of  

the  large  intes2nes  and  the  vaginal  tract.    

•  Prevents  the  coloniza5on  of  invading  pathogenic  bacteria  by  

aTaching  to  the  intes2nal  wall,  crowding  out  and  taking  
nutrients  from  these  unfriendly  bacteria  and  yeast    

•  Produces  lac2c  and  ace2c  acids,  which  lower  the  intes2nal  pH  
and  further  inhibit  the  undesirable  bacteria  from  growing  

•  Enhances  the  assimila2on  of  minerals  such  as  iron,  calcium,  

magnesium  and  zinc  
Bifidobacterium  Longum  

•  Very  abundant  organism  found  in  the  large  intes2ne.      

•  Prevents  the  coloniza2on  of  invading  pathogenic  

bacteria  (unfriendly  yeast  and  bacteria)  

•  Produces  lac2c  and  ace2c  acids  that  lower  the  

intes2nal  pH  and  and  further  inhibit  the  undesirable  
bacteria  

•  Reduces  the  frequency  of  gastrointes2nal  disorders  

(diarrhea,  nausea,  etc.)  during  an2bio2c  use  
Enteroccocus  Faecium  

•  Nutri2onal  support  of  diarrheal  diseases,  especially  in  cases  

where  pathogenic  microbes,  such  as  rotavirus,  invade  the  
bowel  

•  Transiently  colonizes  the  GI  tract  

•  Lowers  LDL  cholesterol    

•  More  effec2ve  than  L.  acidophilus  in  shortening  the  

dura2on  of  diarrheal  episode  

•  Natural  resident  of  the  human  intes2nal  tract  

Lactobacillus  Acidophilus  

•  One  of  the  most  important  microorganisms  found  in  the  small  intes2nes  

•  Implants  on  the  intes2nal  wall,  and  in  the  lining  of  the  wall  of  the  vagina,  
cervix,  and  urethra  

•  Many  cri2cal  func2ons  including  inhibi2ng  pathogenic  organisms  and  

preven2ng  them  from  mul2plying  and  colonizing  

•  Acts  as  a  natural  an2bio2cs  (secre2ng  lactocidin,  acidophilin,  etc.)    

•  Enhances  resistance  and  immunity  

•  An2microbial  ac2vity  against  Staphylococcus  aureus,  Salmonella,  E.coli  and  

Candida  albicans  
Lactobacillus  brevis  

•  Lac2c  acid  producing  organism  important  in  

the  synthesis  of  vitamins  D  and  K  

•  Both  deficient  in  ASD  and  used  to  promote  

speech  
Lactobacillus  casei  

•  Immuno-­‐modula2ng  effects  effects  provided  

•  Produces  bacteriocins  =  inhibi2on  of  

pathogenic  bacteria  in  the  small  intes2ne  
Lactobacillus  bulgaricus  

•  Transient  microorganism  that  does  not  implant  in  

the  intes2nal  tract  

•  Provides  an  important  protec2ve  role  

•  Helps  lactobacilli  and  bifidobacteria  grow    

•  S2mulates  produc2on  of  interferon  and  tumor  

necrosis  factor  =  keyrole  in  modula2ng  the  
immune  system  
Lactobacillus  sporogenes  

•  Lowers  LDL  

•  Inhibits  growth  of  pathogenic  microbes  

•  Effec2ve  for  treatment  of  cons2pa2on  

•  Transient  member  of  gut  flora  

•  Produces  lac2c  acid  

Lactobacillus  salivarius  

•  Lactobacillus  salivarius  normalizes  the  gut  flora    

•  Treats  chronic  bowel  condi2ons  

•  Inhibitor  of  H.  pylori  

•  An2-­‐inflammatory  

•  Used  aoer  an2bio2cs  and  chemotherapy  

•  Acts  on  yeast  

•  Breaks  down  protein  into  usable  amino  acids  

Lactobacillus  Reuteri    

•  A  "major  component"  of  Lactobacillus  species  in  the  gut  

•  Important  in  promo2ng  the  health  of  the  host  organism  

•  Reuterin  inhibits  harmful  Gram-­‐nega2ve  and  Gram-­‐posi2ve  bacteria  as  well  as  
yeasts,  fungi  and  protozoa  

•  Secretes  sufficient  reuterin  to  cause  an2-­‐microbial  effects    

•  4-­‐5  2mes  the  amount  of  reuterin  is  needed  to  kill  "good"  gut  as  "bad",  this  
would  allow  L.  reuteri  to  remove  gut  invaders  while  keeping  normal  gut  flora  
intact  

Does  this  sound  like  a  good  alterna1ve  to  an1bio1cs?  

Bacillus  sub5lis  

•  Transient  member  

•  Can  promote  drama2c  healing  benefits  

•  Dysentry  treatment  –  WWII  

•  Ac2vates  immune  system  

•  Acts  strongly  against  pathogens  

•  Ac2vates  IgG,  IgM  and  IgA  

•  An2-­‐viral  
Lactobacillus  GG  

•  Is  resistant  to  stomach  acid  and  bile,  allowing  it  to  

survive  its  passage  through  the  diges2ve  tract  and  
reach  the  large  intes2ne  intact  

•  Excep2onal  ability  to  adhere  to  the  intes2nal  mucosa  

and  proliferate  

•  Acts  on  Clostridia,  yeast  

•  Increases  immune  func2on  

•  Breaks  down  gluten  and  casein  pep2des  

Streptococcus  themophilus  

•  Efficient  in  breaking  down  lactose  by  

producing  the  enzyme  lactase  

•  Cytokine  produc2on  is  s2mulated  in  2ssue  

cultured  cells  by  this  bacterium  

•  Acts  against  beta-­‐hemoly2c  strep  

Lactobacillus  rhamnosus    

•  Primarily  found  in  the  small  bowel   •  Down-­‐regulates  hypersensi2vity  

and  vaginal  tract     reac2ons  and  intes5nal  
inflamma5on    
•  Inhibits  those  bacteria  involved  in  
vaginal  and  urinary  tract  infec2ons   •  Significant  nutri2onal  benefits    

•  Protects  intes5nal  tract  against   •  Inhibits  early  intes2nal  infec2ons  in  

invasion  of  harmful  microorganisms   infants  

•  Helps  bifidobacteria  populate  and   •  Inhibits  the  growth  of  streptococci  

produces  biologically  desirable  lac2c   and  clostridia  
acid  
•  Favourably  affects  lactose  intolerance  
Lactobacillus  plantarum  

•  Secretes  the  naturally  occurring   •  Preserves  nutrients,  vitamins,  and  

an2bio2c  lactolin   an2oxidants  
•  Synthesizes  the  amino  acid  L-­‐
lysine  which  is  an2-­‐viral     •  Eliminates  toxic  components  from  
food  
•  Produces  glycoly2c  enzymes  
shown  to  degrade  cyanogenic  
glycosides     •  Helps  preserve  nutrients  such  as  
omega-­‐3  faTy  acids  but  also  
•  Effec2ve  in  elimina2ng  nitrates   increase  their  content  
while  producing  nitric  oxide  
•  Breaks  down  proteins  into  usable  
•  Reduces  gut  pathogens   amino  acids  
Detoxifica5on  
•  Household  cleaners  
•  Bisphenol  A  
•  Phthalates  –  odours  
•  Plas2cs  
•  Pes2cides  -­‐  biological  
•  Mercury  found  in  tuna  
•  Food  Colouring  -­‐  Tartrazene  
Tartrazine:  Yellow  dye  no.5  

•  Toxic  colour  in:  

•  Candy,  soo  drinks,  chips,  cereal,  
cakes,  pastries,  soups.  
•  Moisturizers,  soap  and  shampoo  
•  Brand  names  include  Mountain  
Dew,  Doritos,  and  Nachos      
•  Studies  show  improvement  in  
symptoms  aoer  elimina2on  of  food  
addi2ves.  
 Phase  I  

•  Oxida2on,  reduc2on,  hyrolysis,  hydra2on,  dehalogena2on  

•  B2,  B3,  B6,  B12  
•  Folic  acid  
•  Glutathione  
•  Flavonoids  
•  Phospholipids  
Intermediary  metabolites  

•  Vitamin  A,  C,  E  

•  Selenium  
•  Copper  
•  Zinc  
•  Manganese  
•  CoQ10  
•  Thiols  –  found  in  garlic,  onions  and  cruciferous  vegetables  
•  Bioflavonoid  
•  Silymarin  
•  Oligomeric  proanthocyanidins  -­‐  OPCs  
 Phase  II  

•  Sulfa2on,  glucuronida2on,  glutathione  conjuga2on,  

acetyla2on,  amino  acid  conjuga2on  (glycine,  taurine,  
glutamine,  ornithine,  arginine)  
•  Methyla2on  
•  NAC  
•  Cysteine  
•  Methionine  
Sleep  

•  Scavenges  free  radicals  in  the  brain  

•  Muscle  building  
•  Liver  regenera2on  
•  Regula2on  of  sugar  levels  
Sleep  

•  Rou2ne  
•  Probio2cs  -­‐Yeast  or  other  microbes?  
•  Protein  
•  Melatonin  
•  Seda2ve  herbal  medicines  
•  Homeopathics  
Adrenal  Support  

•  Sympathe2c  overload  
•  Not  enough  GABA  –  too  much  glutamate  
•  Impaired  detoxifca2on    
•  Increased  inflamma2on  
•  Gut  issues  
Adrenal  Support  
•  B  vitamins  –  B5  and  B6  
•  Magnesium  
•  Licorice  
•  Rou2ne  and  Sleep  
•  Magnesium  –  green  leafy  veggies,  pumkins  
seeds  
•  Decreasing  stressors  
B12  Therapy  
•  Oral  –  3-­‐5%  
•  Injec2on  –  100%  www.drneurbrander.com  
Caring  for  the  Caregiver  

•  Methyla2on  issues  
•  Sleep  
•  Stress  System  Support  
•  Diges2on  and  Liver  health  
•  Taking  2me  for  you  and  your  partner  
Ge#ng  Started  
•  Tes2ng  
•  One  step  at  a  2me  
•  Marathon  not  a  sprint  
•  One  good  change  can  shio  development  
 Challenge  your  health  care  
professionals  

Advocate  for  your  child  

Biomedical  treatment  can  help  the  

majority  of  children  with  ASD