Antibodies.

By
Molly Bolder
INT. BLOOD VESSEL - DAY
A fade from black reveals the microscopic world. A variety
of cells are flowing through a blood vessel in the body. As
groups of blood cells pass by a group of B cells slowly
float along the bottom of the blood vessel.
V.O.

Everyday, thousands of microscopic processes occur within

the body.
One of these is the immune system’s response to foreign
cells.
A lone bacteria cell enters the shot and passes through.

V.O.
This bacteria cell has entered the body and will replicate
itself into something more sinister if left unchallenged.

Brushing the group of B cells. One B cell with a matching

antibody rises up and grabs it.
V.O.
However, this bacteria carries unique antigens that are
recognised by the antibodies on a B cell. Antibodies
receptors vary with every B cell but when they match an
antigen they take hold of it.
As they flow together down the vein the B cell connects
itself to the bacteria and begins engulfing it along with
the antibody it is attached to. As it does so it slows to a
stop and begins to break it down.
V.O.

Once the antibody has taken hold of the antigen, the B cell
will pull in and engulf both the bacteria and the antibody
it is connected to.
The B Cell as it begins to produce an MHC2 protein which
holds up a piece of the bacteria that the B cell absorbed.
The B cell is now a professional antigen presenting cell.
V.O.
When the bacteria is destroyed, the B cell will become a
professional bacteria presenting cell. It will present a
small piece of the bacteria on its surface to alert other
white blood cells.
The shot fades to black.
 2.

INT. BLOOD VESSEL - DAY

Opening from black, the B cell is passed by a group of
helper T cells as they enter the vein.
V.O

The cell that approaches the B cell is a helper T

cell. This cell also has receptors that match the presented
antigen.

One of these helper T cells has receptors that match the

bacteria presented exactly and reaches for it. The T cell
binds to the protein and bacteria using its receptors thus
activating the B Cell.
V.O.

The helper T cell uses its receptor to connect to the piece

of bacteria and the B cell. This connection then activates
both cells.
The helper T cell emits cytokines to enter other cells.

V.O.
The helper T cell produces small proteins called Cytokines.
These proteins spread through the blood stream and enter
other B cells with the correct antibody.

The cells perforated by the cytokines then replicate at a

faster rate.
V.O.

These B cells then replicate themselves at a higher rate in

order to protect the immune system.
The activated B cell then matures and releases many of the
same kind of antibody.

V.O.
The original B cell then matures and releases many loose
antibodies into the blood stream. These free flowing
antibodies carry the receptors that match the antigen and
are free to defend the body.
Scene fades to black.