CURRICULUM VITAE

MARLENE B. ZURAEK

14 Big Sur Way

Pacifica, CA 94044
Home: (650) 355-9577
Cell: (415) 260-6344
Work: (415) 353-9288
E-mail (home): mz3d9be2@westpost.net
E-mail (work): Marlene.Zuraek@ucsfmedctr.org
EMPLOYMENT HISTORY
RESEARCH ASSOCIATE/ANALYST
February 2003-Present
Surgical Oncology and Medical Oncology GI Research and Clinical Trials
University of California San Francisco Comprehensive Cancer Center
* Participated in the development of a Clinical Operations Plan and Data Managem
ent Plan for a multi-center Investigator-sponsored Phase II clinical trial by ap
plying clinical and scientific expertise.
* Primary liaison between UCSF and other investigative sites for a Phase II inve
stigator-sponsored multi-center clinical trial regarding protocol inquiries, ame
ndments, patient exemptions.
* Managed all research activities including study start-up, site initiation, stu
dy conduct, data management and monitoring.
* Designed study specific electronic and paper CRFs.
* Prepared and submitted regulatory documents to the Institutional Review Board.
* Create standard reports for interim safety and efficacy analysis, data managem
ent audit and ad-hoc needs.
* Ensure accuracy, consistency and completeness of clinical data through edit ch
ecks,
manual review of CRFs and use of external systems such as SAS; manage discrepanc
ies and data queries.
* Responsible for the project management and data management of a multi-center
NIH-funded genetic trial on molecular markers involving 2,000 patients, which ac
companied a Phase III clinical trial in colon cancer.
* Perform literature searches, participate in data analysis and scientific writi
ng of abstracts and manuscripts for presentation at scientific meetings and publ
ication in peer-reviewed scientific journals.
* Plan, write and execute statistical programs using SAS for analysis of researc
h data, data cleaning and reporting. Create customized datasets, tables, figures
and listings to support ongoing studies.
* Design and review database structures; maintain and modify a relational clinic
al research database in Filemaker Pro and e-Velos. Supervise data entry staff.
CLINICAL RESEARCH ASSOCIATE/DATA MANAGER
March 2000-January 2003
Surgical Oncology Clinical Research Office, Dept. of Surgery
University of California San Francisco Comprehensive Cancer Center
* Coordinated and implemented Phase II clinical trials according to protocol. Pr
epared and submitted regulatory documents to the Institutional Review Board.
* Performed data management and statistical analyses of clinical data to support
various research studies, using SAS, STATA and Excel. Maintained and managed th
e Surgical Oncology clinical database using Filemaker Pro.
PROGRAM OFFICER
January 1992-April 1993
Immunizable Diseases Control Program
Community Health Program (NGO)
Manila, Philippines
* Managed the following program components-medical services, training, health ed
ucation, nursing and research. Responsible for planning, implementation, monitor
ing and evaluation of immunization projects in urban underserved areas.
* Acted as Public Health Physician and resource speaker for training and educati
on activities on immunization and infectious diseases. Coordinated with governm
ent agencies, community leaders, and non-government agencies in planning and imp
lementing the project. Personnel Manager and supervisor of project staff and com
munity health workers. Wrote project proposals for funding. Approved all financi
al transactions of project with the administration
ASST. PROGRAM OFFICER/MEDICAL
SERVICES OFFICER
January 1991-December 1991
Nutrition program
Community Health Program (NGO)
Manila, Philippines
* Assisted Program Officer in the management of a nutrition program and establis
hment of a Health and Nutrition Rehabilitation Center in an urban-depressed comm
unity. Served as Public Health Physician in the center and supervised clinic nur
ses, dentists, nutritionist and community health workers.
* Coordinated with leaders and government agencies in the community in treating
malnutrition, especially second and third degree malnourished pre-schoolers.
VOLUNTEER PHYSICIAN
September 1990-Dec. 1990
Community Health Program
Performed outreach medical and immunization sessions in urban depressed and disa
ster-stricken areas
CLINIC PHYSICIAN
June 1990-December 1990
San Lorenzo Medical Clinic
Novaliches, Philippines
COMPUTER SKILLS
SAS (Base, STAT), STATA, Filemaker Pro, Excel, Access, Word, PowerPoint
RELEVANT COURSES
Good Clinical Practice (GCP)/ICH and Human Subjects Protection Training Course
UCSF
SAS Programming for Clinical Trials
(Part of Clinical Trials Design and Management Certification)
UC Santa Cruz Extension
January 20- March 31, 2010
Database Management Systems for Clinical Research,
Regression Methods (Linear, Logistic, Survival, Repeated Measures),
ANOVA, Contingency Table Analysis, Non-parametric tests
(UCSF Dept. of Epidemiology and Biostatistics)
SAS Programming
(SAS Institute)

EDUCATION
Doctor of Medicine
University of the East-Ramon Magsaysay Memorial Medical Center
Manila, Philippines
Bachelor of Science in Public Health
University of the Philippines
Manila, Philippines

HONORS/AWARDS
UCSF School of Medicine Staff Performance Award (Tier 1), 2002 and 2006
Philippine National Government Scholar
1980-1984
PUBLICATIONS
Wang YC Iezza G, Zuraek MB, Jablons DM, Theodore P, Bergsland EK, Donner DB, Wa
rren RS, Nakakura EK. Lack of Nkx2.2 expression in Bronchopulmonary Typical Carc
inoid Tumors: Implications for Patients with Neuroendocrine Tumor Metastases and
Unknown Primary Site. J Surg Res. 2010 Sep; 163(1):47-51.
Wang S, Parekh J, Zuraek M, Venook A, Bergsland E, Warren R, Nakakura E. Identif
ication of Unknown Primary Tumors in patients with Neuroendocrine Liver metastas
es. Arch Surg. 2010 March; 145(3): 276-80
Wang YC, Zuraek MB, Kosaka Y, Ota Y, German MS, Deneris ES, Bergsland EK, Donner
DB, Warren RS, Nakakura EK.The ETS oncogene family transcription factor FEV ide
ntifies serotonin-producing Cells in normal and neoplastic small intestine.
Endocr Relat Cancer. 2010 Feb 18; 17(1):283-91
Wang YC, Gallego E, Yuan X, Matli M, Iezza G, Choo S, Zuraek M, Gogia R,
German F, Donner D, Bergsland E, Warren R, Nakakura E. Homeodomain transcription
factor Nkx2.2 functions in immature cells to control enteroendocrine differenti
ation and is expressed in gastrointestinal neuroendocrine tumors. Endocr Rel Can
cer.
March 2009; 16(1): 267-279
Aslam R, Coakley F, Williams G, Yeh B, Joe B, Zuraek M, Warren R. Prognostic Imp
ortance of Superior Diaphragmatic Adenopathy at CT in Patients with Resectable H
epatic Metastases from Colorectal Carcinoma. J Comput Assist Tomogr. March/April
2008; 32(2):173-177
Mehta KR, Nakao K, Terdiman JP, Zuraek MB, Ruan D, Bergsland EK, Venook AP, Mo
ore DH, Tokuyasu T, Jain A, Warren RS, Waldman FM. Fractional Genomic Alteration
Detected by Array-based Comparative Genomic Hybridization Independently Predict
s Survival in Patients with Colorectal Cancer Liver Metastasis. Clinical Cancer
Research. March 2005; 11(5): 1791-1797
Norton JA, Warren RS, Kelly MG, Zuraek MB, Jensen RT. Aggressive Surgery for Met
astatic Liver Neuroendocrine Tumors. Surgery. December 2003; 134(6): 1057-1065.

ABSTRACTS
Wong M, Wang Y, Iezza G, Zuraek M, Yuan X, Donner D, Hanahan R, Warren R, Bergsl
and E, Nakakura E. Immunohistochemical analysis of the mTOR pathway in Neuroendo
crine tumors of the pancreas and small intestine. Presented at the American Soci
ety of Clinical Oncology Gastrointestinal Cancers Symposium, San Francisco, CA,
January 2009 (Poster).
Ruan D, Bergsland E, Moalem J, Kebebew E, Zuraek M, Griffin A, Rowe M, Warren R.
Primary Tumor Characteristics are associated with Surgical Outcomes after Hepate
ctomy for Colorectal Cancer Metastases. Presented at the Pacific Coast Surgical
Association Annual Meeting, February 2008, San Diego, CA (Poster).
Ruan D, Zuraek M, Bergsland E, Donner D, Nakakura E, Venook A, Warren R.
Mitogen inducible factor-6 expression is inversely associated with survival afte
r resection of colorectal liver metastases. Presented at the American Society of
Clinical Oncology Gastrointestinal Cancers Symposium, Orlando, Florida, January
2008 (Poster).
Ruan D, Bergsland E, Moalem J, Farkus R, Griffin A, Zuraek M, Rogers O, Warren R
. Racial Disparities in Survival after hepatectomy for Colorectal Cancer liver m
etastases. . Presented at the American Society of Clinical Oncology Gastrointest
inal Cancers Symposium, Orlando, Florida, January 2008 (Poster).
Warren R, Bergsland E., Zuraek M, Ruan, D. Predictors of outcome after resection
of Hepatic metastases in colorectal cancer. Presented at the American Society o
f Clinical Oncology Gastrointestinal Cancers Symposium, San Francisco, CA, Janua
ry 2004 (Poster).
Ruan D, Zuraek M, Bergsland E, Venook A, O'Neill B, Warren RS. Late Vascular Com
plications from Hepatic Artery Infusional Chemotherapy Catheters. Presented at t
he 2004 Surgical Society Oncology Scientific Meeting, New York (Poster).