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Pathophysiology of Stab wound

Risk factors :

knife, samurai, blade, something sharp Disruption of Cell Membrane Start of Inflamatory Process entrance of pyrogens Hypothalamus (Prostaglandin Production) Mast Cells Fever (Value) Leukotrienes interleukin -1

Bradykinin

Prostaglandin Vasoconstriction

Histamine

(Value)

Vasolidation Prevent spill of blood

increase WBC =

Increase permability Diapedisis or Accumulation of WBC to the interstitial compartment Phagocytosis Swelling Exudates Ruptured of sepsis affected parts

Pain If treated treated If NOT

RECOVERY

Septic Shock :

Decrease Blood Pressure Decrease Blood Volume DEATH

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