Product Information

S1260 AMG-073
Technical Data:
M.Wt: Formula: Solubility: Purity: Storage: CAS No.: 393.87 C22H22F3N.HCl DMSO 99% at -20 2 years 364782-34-3
N H CF3 HCl

Novel Life Science Reagents

for Cell Signaling Research

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Synonyms: Cinacalcet

hydrochloride

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Biological Activity
AMG-073(Cinacalcet hydrochloride) represents a new class of compounds for the treatment of hyperparathyroidism known as calcimimetics, which reduce parathyroid hormone (PTH) synthesis and secretion by increasing the sensitivity of the parathyroid calcium-sensing receptor (CaR) to extracellular calcium. The current study evaluates the efficacy and safety of AMG 073 when added to conventional treatment of secondary hyperparathyroidism in end-stage renal disease (ESRD). [1]

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References
[1] Quarles LD et al. J Am Soc Nephrol. 2003 Mar;14(3):575-83.

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Please inspect packages immediately upon receipt and notify customer service within 3 days of delivery of any damage or discrepancies.Our team will take quick and appropriate action to correct any problem.

MSDS & CoA

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Goods ordered in error can only be accepted for return if made within 3 days of delivery, are unopened,have been stored correctly and are in good condition. Should you wish to return any item(s), prior authorization must

Notes
PLEASE KEEP THE PRODUCT UNDER -20 FOR LONG-TERM STORAGE. NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products, stored under the recommended conditions, are stable for two years. Products are sometimes shipped at a temperature that differs from the recommended storage temperature,most are recommended stored at -20 Many products are stable in the short-term at temperatures that differ from that . required for long-term storage. We ensure that the product is shipped under conditions that will maintain the quality of the product, but save your shipping charges by using the most economical storage conditons for an overnight shipment. Upon receipt of the product, follow the storage recommendations on the product data sheet.

be received from our customer service team. Returns accepted will be subject to a 30% restocking charge.

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