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NURS 1566 Clinical Form 3: Clinical Medications Worksheets

(You will need to make additional copies of these forms)

Generic Name Trade Name Classification Dose Route Time/frequency

irbesartan Avapro angiotensin II 300 mg PO daily
Peak Onset Duration Normal dosage range
3-14 hrs Within 2 hrs 24 hrs 150 mg once daily; may be increased to 300 mg once daily.
Patients receiving diuretics, who are volume depleted, or
who are being hemodialyzed--initiate with 75 mg/day.Type
2 diabetic nephropathy--300 mg once daily
Why is your patient getting this medication For IV meds, compatibility with IV drips and/or
Diabetic neuropathy, HTN solutions

Mechanism of action and indications Nursing Implications (what to focus on)

(Why med ordered) Contraindications/warnings/interactions
Blocks vasoconstrictor and aldosterone-producing Hypersensitivity. Use cautiously in: CHF (may result in
effects of angiotensin II at receptor sites, including azotemia, oliguria, acute renal failure and/or death).
vascular smooth muscle and the adrenal glands Volume- or salt-depleted patients or patients receiving high
doses of diuretics (correct deficits before initiating therapy
or initiate at lower doses). Black patients (monotherapy
may not be effective). Impaired renal function due to
primary renal disease or CHF (may worsen renal function).
Obstructive biliary disorders or hepatic impairment (lower
initial doses of losartan, temisartan, or valsartan
Common side effects
No common side effects. Potential life threatening side
Interactions with other patient drugs, OTC or Lab value alterations caused by medicine
herbal medicines (ask patient specifically) Monitor serum creatinine and urinary protein in patients
↑ antihypertensive effects with other treated for diabetic nephropathy. May rarely cause ↑ in
antihypertensives (labetalol) and diuretics (Lasix). BUN and serum creatinine. May cause ↑ serum bilirubin.
Risk of hypotension ↑ by concurrent diuretics May occasionally cause hyperkalemia.
(Lasix) (use lower initial doses). Be sure to teach the patient the following about this
Emphasize the importance of continuing to take as
directed, even if feeling well. Take missed doses as soon as
remembered if not almost time for next dose; do not double
doses. Medication controls but does not cure hypertension.
Instruct patient to take medication at the same time each
day. Gradual reduction of dose prior to discontinuation is
suggested. Encourage patient to comply with additional
interventions for hypertension (weight reduction, low-
sodium diet, discontinuation of smoking, moderation of
alcohol consumption, regular exercise, stress management).
Instruct patient and family on proper technique for
monitoring blood pressure. Advise them to check blood
pressure at least weekly and to report significant changes.
Caution patient to avoid sudden changes in position to
decrease orthostatic hypotension. Use of alcohol, standing
for long periods, exercising, and hot weather may increase
orthostatic hypotension. May cause dizziness. Caution
patient to avoid driving or other activities requiring
alertness until response to medication is known. Advise
patient to consult health care professional before taking any
OTC or herbal cough, cold, or allergy remedies or other
medications. Instruct patient to notify health care
professional of medication regimen prior to treatment or
surgery. Emphasize the importance of follow-up exams to
evaluate effectiveness of medication.
Nursing Process- Assessment Assessment Evaluation
(Pre-administration assessment) Why would you hold or not give this Check after giving
Assess blood pressure (lying down, med? Decrease in blood pressure
sitting, standing) and pulse periodically Hypotension. Occurrence of without appearance of
during therapy. Monitor frequency of unexpected, intolerable side effects. excessive side effects.
prescription refills to determine Slowed progression of
adherence. Assess patient for signs of diabetic nephropathy.
angioedema (dyspnea, facial swelling). Reduced risk of stroke.
May rarely cause angioedema; more
common in patients who have had
angioedema with ACE inhibitors.