Code No: RR322305

Set No. 1

III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2008 IMMUNOLOGY (Bio-Technology) Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks 1. Explain any two (a) adjuvants. (b) complement. (c) MHC. (d) T cells. 2. Dene immunoglobulin and explain about its structure and function. [3+8+5] [8+8]

3. (a) What is the diagnostic method of shigella and list out the other applications of it? [5+3] (b) Explain the diagnostic method of diphtheria and list its other applications. [5+3] 4. Dene a cytokines and explain about their role in immune response, and its products. [2+10+4] 5. Dene hybridoma and explain monoclonal antibody production? 6. Explain the overview of signal transduction during T-cell activation? 7. Discuss about the puried macromolecules as vaccines? [3+13] [16] [16]

8. Describe dierent types of systemic autoimmune diseases and explain in detail about anyone of them? [4+12]

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Code No: RR322305

Set No. 2

III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2008 IMMUNOLOGY (Bio-Technology) Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks 1. What is meant by Hematopoiesis and explain its role in the generation of various immune cells. [3+13] 2. Write a short notes on : (a) antigen receptors. (b) VL regions. (c) VH regions. (d) Hinge region. 3. What are monoclonal antibodies and explain its importance? 4. What a short notes on: (a) interferons. (b) interlevkines. (c) Tc cells. (d) TH cells. 5. Give an account on immunosuppressive therapy? 6. Give an account on the precipitation reactions of antigens with antibodies? 7. Give an account on the mediators of type I hypersensitivity? 8. What is meant by HLA & explain HLA typing? [16] [16] [16] [8+8] [12+4] [8+8] [8+8]

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Code No: RR322305

Set No. 3

III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2008 IMMUNOLOGY (Bio-Technology) Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks 1. What is meant by complement and explain in detail the dierent pathways of complement system? [3+13] 2. Explain the process involved in the activation of B cells. 3. What are monoclonal antibodies and explain its importance? 4. What are interferons and explain about various types of cytokines . 5. (a) Describe the process for culturing of the stem cells? (b) Explain the role of stem cells in controlling Immunodeciency? 6. Explain dierent types of forces that causes antigen - antibody interactions? [16] 7. Dene hypersensitivity & discuss dierent types of hypersensitivity reactions?[3+13] 8. Describe dierent types of systemic autoimmune diseases and explain in detail about anyone of them? [4+12] [16] [12+4] [8+8] [8+8]

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Code No: RR322305

Set No. 4

III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2008 IMMUNOLOGY (Bio-Technology) Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks 1. What are the various cells involved in the immune response and explain about their role in immune response. [3+13] 2. Write a short notes on : (a) IgG. (b) IgA. (c) VH regions. (d) Antibody valence. 3. Write a short notes on: (a) congenic. (b) MHC class I (c) MHC class II (d) MHC class III 4. What are interferons and explain about various types of cytokines . 5. Dene hybridoma and explain monoclonal antibody production? [8+8] [3+13] [8+8] [8+8]

6. Dene agglutination and its mechanism in antigen - antibody interactions?[11+5] 7. Describe the various types of type III hypersensitivity? 8. Give an account on the signicance of autoimmunity in Immunology? [16] [16]

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