CYSTS 0F JAWS O 0RAL S0FT TISSUES

ueflnlLlon
1 9fLhologlcfl cflLy llned wholly [ ln pfL by eplLh hflng fluld [ semlfluld conLenLs
2 9fLhologlcfl cflLy hflng fluld [ semlfluld conLenLs whlch noL been cefLed by fccumulfLlon of pus

Pl1nLl4L cY515 NONPl1nLl4Ll2u PklM4kY 8ON cY515
CDCN1CGLNIC CS1S
O plLh llnlng deled fom esldue of LooLhfomlng ogfn
LSIDUL 1LS GIVL ISL 1C
uenLfl lfmlnf
esLs/glfnd of Sees
CdonLogenlc kefLocysL
8educed enfmel
eplLh
uenLlgeous cysL
pffdenLfl cysL
8esLs of Mflfssez 8fdlculf cysLs

O SCLl1A8? 8Cn C?S1S (slmple LfumfLlc hfemohfglc
bone cysL)
O Aneuysmfl bone cysL
O SLffne's ldlopfLhlc bone cflLy
1LS CI
CDCN1CGLNIC CS1 NCNCDCN1CGLNIC CS1
uvLOPMN14L lNlL4MM41OkY
O nfsopflfLlne ducL (lnclsle cfnfl)
cysL
O nfsolfblfl (nfsofleolf) cysL
O Medlfn cysL




O CdonLogenlc
kefLocysL
O uenLlgeous(folll
culf) cysL
O upLlon cysL
O LfLefl
pelodonLfl
cysLs
O lnglfl cysL
O lfndulf
odonLogenlc cysL
O 8fdlculf
cysL(denLfl cysLs)
Aplcfl
LfLefl
8esldufl

O 9ffdenLfl cysL

CCM9Cnn1 Cl C?S1
1 Lumen
2 plLhellfl llnlng
3 llbous cfpsule


uvLOPMN14L
OuON1O6Nlc
cY515

u5cklP1lON5

cLlNlc4L k4ulO6k4Pnlc l41uk5

P41nO6N5l5 xP4N5lON
M4ckO5cOPlc
nl51OP41nOLO6Y

DLN1IGLCUS
CS1
nclose pfL [ fll of cown of
uneupLed LooLh

ALLfched Lo fmelocemenLfl [xn

Alse ln folllculf L coelng fully
fomed cown of uneupLed LooLh

Mechfnlsm of expfnslon sfme wlLh
8AulCuLA8 C?S1 (unlcenLlc
bflloonlng)

8one esoblng ffcLo
9osLfglfndln 2
lnLeleukln1

PypeLonlc conLenL

8fLe of expfnslon
8fpld ln chlld
Slowe ln fdulL

CenLfl Lype
CysL compleLely suound
cown of fssoclfLed LeeLh

LfLefl Lype
CysL po[ecL lfLeflly fom
slde of LooLh
x compleLely enclose cown
Mfny deLecLed ln fdolescenL young
fdulL peflence up Lo 3
Lh
decfde

Common ln mfn mfndlble

MosL lnole LeeLh whlch fe
commonly lmpfcLed [ eupL lfLe

uncommon fssoclfLed wlLh
Supenumefy LeeLh
Complex compound
odonLomes

Mfnd 3
d
M mfx pem Cfnlne
mfx 3
d
M mfnd 9M

9fln ls noL f fefLue unLSS Lhee ls
second lnflfmmfLlon

Welldeflned unlloculf fdlolucency
fssoclfLed wlLh cown of uneupLed
LooLh


unknown sLlmulus unclef
mechfnlsm of cysL fomfLlon

CysL deelop bLwn cown of
uneupLed LooLh 8

PypoLhesls(1)
Compesslon of folllcle by
eupLlng lmpfcLed LooLh

enous pessue ln folllcle

LfnsudfLlon of fluld
poollng of fluld

SepffLe folllcle fom cown
cysL fomfLlon

PypoLhesls(2)
9ollfefLlon of ouLe lfye
of 8

8efkdown of cells wlLhln
eplLh lslfnds

CysL fomfLlon

PypoLhesls(3)
Spefd of pelfplcfl lnflfm
fom declduous pedecesso

lnole folllcle of pemfnenL
successo

AccumulfLlon of
lnflfmmfLoy exudfLes

CysL fomfLlon
1hln egulf lfye (23 cells Lhlck)

nonkefLlnlzed sLfLlfled sq [
low cuboldfl eplLh

8esemble 8

Mucous cell meLfplfslf
Common
wlLh fge

plLhellfl dlsconLlnulLles obseed

Llnlng suppoLed by flbous
connecLle L cfpsule
lee fom lnflfmmfLoy
cell lnfllLfLlon unLSS
Lhee ls second lnflfm

CholesLeol clefLs

lslfnd of odonLogenlc eplLh

unlcysLlc fmeloblfsLomf
Llned by
fmeloblfsLomfLous
eplLh
9ollfefLe lnLo cysL
lumen

9oLelnfceous yellowlsh fluld
cholesLeol cysLfl




LU1ICN CS1 1ue denLlgeous cysL

Alse ln exLffleolf locfLlon
lnole boLh declduous pemfnenL

llucLufnL swelllng on fleolf mucosf
Sfme wlLh denLlgeous Sfme wlLh denLlgeous

8lulsh ln colo

Pfemohfge lnLo cysL cflLy fs esulL
of Lfumf
CDCN1CGLNIC
kL1CCS1
uncommon leslon unusufl gowLh
pfLLen

x uSC8l8 fs fny odonLogenlc cysL
poduclng kefLln
8efes Lo speclflc
cllnlcopfLhologlcfl enLlLy

8fely poduce kefLln by
meLfplfslf
8fdlculf cysL
uenLlgeous cysL
plLhllnlng usuflly
oLhokefLlnlzed
x show egulf odeed
eplLh dlffeenLlfLlon
x fssoclfLed wlLh n8CCS

1endency Lo ecu

mulLlple cysL fssoclfLed wlLh
nAIClu 8ASAL CLL CA8ClnCMA
S?nu8CM(C8Lln S?nu8CM)
fuLosomfl domlnfnL
muLfLlon of Lumou
suppesso gene on
chromose 9q(ptch gene)
lmpoLfnL ln nomfl gowLh
deelopmenL of Llssue n
ogfns

MAnllS1A1lCnS
SkIN mulLlple n8CCS occu
fnywhee fppef found pubeLy
fge

ClmulLlple odonLo kefLocysL

SkLLL1Llb fnomflles eLebfl
nelop cown of lmpfcLed 3
d
molf

9efk ln 2
nd
3
d
decfde

Common ln mfle mfnd

Mf[olLy occu ln posL Lo 1
sL
9M

MosL common slLe
3
d
molf
Ascendlng fmus of mfnd

lew sympLoms unLSS become
second lnflfm

nlfge pedomlnfnLly ln fnLposL
dlecLlon
Cfn efch lfge slze wlLhouL
cfuslng goss bony expfnslon

x depend on hydosLfLlc osmoLlc
lnLfcysLlc pessue

Alse spofdlcflly

9esenL ln sollLfy leslons

Welldeflned fdlolucency
unlloculf[ mulLlloculf

AssoclfLed wlLh uneupLed 3
d
M

Cown of LeeLh sepffLed fom cysL
cflLy

9elcoonfl L conLlnuous wlLh cysL
cfpsule

Mfy flso pesenL fs deelopmenLfl
CysL enlfgemenL lnole
locfl fef of fcLle gowLh
of cysL wfll
xLenslon of pollfefLlng
fef flong cfncellous spfces
9oducLlon of bone
esoblng ffcLos
8ough coLlcfLed kefLlnlzed
lfye

CysL wfll
1hln folded egulf
conLlnuous lfye of sL sq
eplLh

8fsfl cell lfye
Welldeflned
9fllsfded columnf [
cuboldfl

Supfbfsfl cell
Sfme of sLfLum
splnosum

9ffkefLlnlzed pedomlnfLe

Cells desqufmfLe lnLo cysL lumen

mlLoLlc fcLllLy
lound ln 8ASAL
Su98A8ASAL LA?8

llbous cfpsule
1hln
lee fom lnflfm cell
plLh esldue + sfLelllLe
cysL

lf become second lnflfm
plLh llnlng lose lLs
chffcLe PlsLology
8esemble 8AulCuLA8
C?S1

1endency Lo ecu elfLed Lo
dlfflculLy of suglcfl emofl
defomlLles polydfcLyly clefL
llp/pflfLe

CNScflclfled fflx ceebl bfln
Lumous


LA18AL 98lCuCn1AL C?S1

NC1 DIGNCS1IC
CdonLogenlc kefLocysL
unlcysLlc fmeloblfsLomf

1hln efslly upLued wfll
9o[ecLlons lnLo
cfncellous spfces efslly
Lon
SfLelllLe cysL ln cfpsule

ConLfln Lhlck gey/whlLe cheesy
mfLelfl conslsL of kefLlnous
debls llLLle fee fluld
GINGIVL CS1 Common ln neonfLes

8fe ln fdulL

8efeed Lo fs 8ohn's nodules [
psLeln's pefls

ulsfppef sponLfneously by
3monLhs of fge
Alse fom esL of denLfl lfmlnf
pollfefLe Lo fom smfll kefLlnlzlng
cysL

MosL common ln
lemfles
lnLepemolf eglon of
mfnd

L1LL
LICDCN1L
CS1
uncommon leslon

AssoclfLed wlLh lLfl LeeLh (dlffe
fom LA18AL 8AulCuLA8 C?S1)

Alse flongslde ooL of LooLh (dlffe
fom CuCn1CnlC k8A1CC?S1)
Mflnly ln
Cfnlne
9emolf eglon of mfnd

9esenL wlLh expfnslon

Welldeflned fdlolucenL fef wlLh
scleoLlc mfgln

MulLlloculf

otyro|d esemble Lo bunch of
gfpes
ueled elLhe fom 8 [ esLs of
denLfl lfmlnf
Llned by Lhln nonkefLlnlzed sq
[ cuboldfl eplLh

8esemble 8

locfl plfquellke Lhlckenlng
conLfln glycogen
GLNDUL
CDCN1CGLNIC
CS1
8fe

MosL occu ln fnL pfL of mfnd

Slowgowlng

9flnless
unlloculf [ mulLlloculf
fdlolucency

9oLenLlflly fggessle

Locflly lnfsle nfLue

1endency Lo ecu
Llned by eplLh fylng Lhlckness

Supeflclfl lfye of columnf [
cuboldfl cell

ClusLe fom of mucous cell

CypLs [ smfll cysLllke pesenL
wlLhln Lhlckness of eplLh


lNlL4MM41OkY
OuON1O6Nlc
cY51

u5cklP1lON5

cLlNlc4L k4ulO6k4Pnlc
l41uk5

P41nO6N5l5 xP4N5lON

nl51OP41nOLO6Y
DICUL CS1 MosL common leslon ICL (70)

AssoclfLed wlLh nonlLfl LeeLh

8fe ln declduous denLlLlon

MosL common 2060 ys old

LSIDUL CS1 (20)
8emflned ln [fw

lflled Lo esole followlng exLfcLlon
of lnoled LooLh

L1LL CS1
Iey uncommon

xLenslon of lnflfmmfLlon fom pulp
lnLo lfLefl pelodonLlum flong
lfLefl ooL cfnfl

Cyst content
WfLey sLfwcoloued fluld
semlsolld bownlsh mfLelfl

CholesLeol cysLfl shlmmelng
fppeffnce

PypeLonlc conLenL

Seum poLeln

8efkdown poducL (eplLh
lnflfmmfLoy cell connecLle L
componenL)
xpfnslon of fleolf bone (due Lo
deposlLlon lfye of new bone by
oelylng pelosLeum) dlschfge
Lhough slnus

8fLe of expfnslon Lend Lo ouLsLlp
fLe of subpelosLefl deposlLlon
9ogessle Lhlnnlng of
coLex
Cfn be defomed on
pflplLfLlon
9oduce 'o||can bottom|ng'
'eggshe|| crack||ng'

9efofLe coLex

9esenL fs blulsh flucLufnL
submucosfl swelllng

9fln ls seldom unLSS hee ls fcuLe
exfcebfLlon fpldly pogess Lo
fbcess fomfLlon

8ound [ oold fdlolucency fL ooL
fpex

Leslon well clcumsclbed

Suounded by pelphefl fdlopfque
mfgln

ConLlnuous wlLh lfmlnf duf of
lnoled LooLh
9ollfefLlon of esL of Mflfssez
wlLhln chonlc pelfplcfl gfnulomfs

x o// qronu/omos proqress to cyst

Common flndlng
SLfnds sheeLs of sq eplLh
fom pollfefLlon of Lhe esL

Mechfnlsm(1)
uegenefLlon defLh of
cenLfl cells wlLhln
pollfefLlng eplLh

Mechfnlsm(2)
uegenefLlon llqueffcLle
necosls of gfnulfLlon L

Cyst expans|on
xpfnd equflly ln fll dlecLlon fLhe
Lhfn bflloon

8fLe of expfnslon fLe of locfl bone
esopLlon

As bone esobed hydosLfLlc
pessue cfuse cysL Lo enlfge

key polnL
8one esopLlon fllow cysL
expfnslon due Lo hydosLfLlc
pessue cefLed by osmoLlc
gfdlenL
Llned wholly [ ln pfL by non
kefLlnlzed sL sq eplLh

legulf llnlng fy Lhlckness
(newly fomed cysL)

Llnlng moe egulf een
Lhlckness (esLfbllshed cysL)

8efk ln llnlng common

MeLfplfslf of llnlng gle lse Lo
mucous cell

Chonlcflly lnflfmed flbous
Llssue cfpsule

ocket cyst
CysL suound ooL fpex
Pefl ffLe endodonLlc
LefLmenL

Pypeplfslf pedomlnfnL
fefLue
8esulL ln fnfsLomoslng
cods of eplLh
lomlng complex
fcfdes exLend lnLo
suoundlng cfpsule

ConnecLle L cfpsule become
moe flbous wlLh Llme

Less fsculf

8educLlon ln denslLy of
lnflfmmfLoy cell lnfllLfLlon

ueposlL of cholesLeol cysLfls
common

Mufl cholesLeol clefL
fssoclfLed wlLh foelgnbody
glfnL cell

ln pelfplcfl gfnulomf
CholesLeol deled fom
befkdown of 88Cs
8esulL of hfemohfge
lnLo cysL cfpsule
ueposlLs of
hfemosldeln commonly
fssoclfLed wlLh clefLs
(er|'s rxn)

DLN1L
CS1
Celcfl enfmel expfnslon

Alse flongslde pfLly eupLed 3
d

molf

lnoled by pecoonlLls
All occu ln mfnd

MosL fe bucflly [ dlsLobucflly
locfLed

Welldeflned fdlolucency

8elfLed Lo neck of LooLh coonfl 3
d

of ooL
1eeLh show enfmel spu exLend fom
buccfl celcfl mfgln ooL
fucfLlon

xLenslon of lnflfmmfLlon sLlmulfLlng
pollfefLlon

CysLlc chfnge ln 8 coelng
uneupLed pfL of cown
8esemble 8AulCuLA8 C?S1










NONOuON1O6Nlc cY515 cLlNlc4L k4ulO6k4Pnlc l41uk5 nl51OP41nOLO6Y
NSCL1INL DUC1
(INCISIVL CNL) CS1


MosL common Lype

Alse fom eplLhellfl emnfnL of nfsopflfLlne ducL connecL ofl
nfsfl cflLy ln embyo

unknown sLlmulus

Common ln
3
Lh
6
Lh
decfde
Mfles

AsympLomfLlc

Slowly enlfglng swelllng ln fnL eglon of mldllne of pflfLe

ulschfge lnLo mouLh when pfLlenL complfln of sflLy LfsLe

lf second lnflfm pfln mfy occu

MosL common olglnfLe ln lowe pL enLlely wlLhln sofL L of lnclsle
pfplllf (C?S1 Cl 9A9lLLA 9ALA1lnA)
x bony fbnomfllLles

Welldeflned ound oold hefLshfped fdlolucencles

ScleoLlc lm

SL sq eplLh pseudosLfLlfled clllfLed columnf(esplfLoy) eplLh

CollecLlon of mucous glfnd

ScfLLeed chonlc lnflfmmfLoy cell lnfllLfLe

plLh suppoLed by connecLle L cfpsule
9omlnenL neuofsculf bundles


NSCLIL CS1 8fe leslon

Alse ln sofL L of uppe llp [usL below flf of nose

1fdlLlonflly gouped wlLh [fw cysL

Slowly enlfglng sofLLlssue swelllng obllLefLlng nfsolfblfl fold
ulsLoLlng nosLll

Mfybe flse bllfLeflly

Mf[olLy pesenL ln 4
Lh
decfde ln women
Llned by pseudosLfLlfled columnf eplLh

SLfLlfled sq eplLh mucous cell clllfLed cell flso pesenL

unknown feLlology

SuggesLed
Alse fom emnfnL of lowe pL of embyonlc nfsolfclmfl
ducL
,LDIN CS1 8fe leslon
Cccu ln pflfLe / mfnd
8epesenL dlsplfced nfsopflfLlne ducL cysL
lL's ey llkely LhfL Medlfn cysL of mfnd fe of odonLogenlc olgln

NONPl1nLl4Ll2u
PklM4kY 8ON cY515
cLlNlc4L k4ulO6k4Pnlc l41uk5 P41nO6N5l5
SCLI1 CNL CS1 CLhe Lems
Slmple bone cysL
1fumfLlc bone cysL
Pfemohfglc bone cysL
unlcfmefl bone cysL

Common ln
Chllden fdolescenL
9efk lncldence ln 2
nd
decfde
9emolf molf eglon of mfnd

Mf[olLy fe fsympLomfLlc

8fdlolucency of flfble slze legulf ouLllne

9omlnenL fefLue sca||op|ng found bLwn ooLs of sLfndlng LeeLh

Welldeflned mfgln of leslon

8fely mulLlloculf

Cllnlcfl dlfgnosls suglcfl explofLlon
8fpld hefllng

8ough bonywflled cflLy deold of fny deLecLfble sofL L llnlng

CflLy elLhe empLy [ llLLle clef [ bloodsLflned fluld
8ony wflls coeed by dellcfLe lfye of loose fsculf flbous L
conLflnlng 88Cs deposlLs of hfemosldeln plgmenL

x eplLhellfl llnlng

unknown pfLhogenesls

8elfLlonshlp Lo Lfumf eldence noL conlnclng



NLUS,L CNL CS1 8fe ln [fws

Mfy occu flone [ be fssoclfLed wlLh oLhe dlsode of bone

r|mary cyst
Alse ln posL pL of body [ fngle of mfnd
Cccued ln chllden [ young fdulLs
9esenL fs flm expfnslle swelllng cfuslng ffclfl defomlLy
Mfybe fssoclfLed wlLh pfln
unlloculf [ mulLlloculf fdlolucency
8flloonedouL fppeffnce due Lo goss coLlcfl expfnslon

Secondary cyst
AssoclfLed wlLh flboosseous leslon + cenLfl glfnL cell
gfnulomf

nonendoLhellfl llned

8loodfllled spfces sepffLed by cellulf flbous L

MulLlnuclefLed glfnL cell

ldence of old ecenL hfemohfge common ln flbous sepLf

unknown pfLhogenesls

AssoclfLed wlLh hfemodynfmlc dlsLubfnce ln medullfy bone (llke
SCLl1A8? 8Cn C?S1)
S1INL'S IDIC1nIC CNL
CVI1
Llngufl bone defecL

SympLomless

8ound [ ofl welldemfcfLed fdlolucency bLwn pemolf eglon

fngle of [fw

usuflly benefLh lnfelo denLfl cfnfl

8llfLefl fnomfly

Sfuceshfped depesslon [ concflLy

ConLfln ecLoplc sfllfy L ln conLlnulLy wlLh submfndlbulf sfllfy
glfnd

Slflogfphy ldenLlfy sfllfy lncluslons



cY515 Ol 5Ol1 1l55u5
SLIV ,UCCCLLLS DL,CID LIDL,CID CS1S L,nCLI1nLLIL CS1S 1nCGLCSSL CS1S
Alse ln connecLlon wlLh mlno sfllfy
glfnds

Lk1VS1ICN ,UCCCLLLS
Mucous ouLslde upLued ducL

70 flse ln lowe llpcheekfloo of
mouLh

uncommon ln uppe llp (sfllfy Lumou
occu ln uppe llp)

9L 30 ys old

8lulsh LfnslucenL submucosfl swelllng

PlsLoy of epefLed upLue collfpse
efllllng

Muclnfllled cysLlc cflLy [ cflLy llned by
lnflfmed gfnulfLlon L

no eplLhellfl llnlng hfe gfnulfLlon L
x fllled wlLh fluld

lnLfofl [ submenLfl swelllng

Alse fom enclfemenL of eplLh ln
mldllne

Llned by egulf lfye of oLhokefLlnlzed
sL sq eplLh esembllng epldemls

Lumen conLfln kefLlnous debls

Dermo|d
skln fppendfges (hfl folllcles
sebfceous swefL glfnd eecLo
plll muscle)

Lp|dermo|d
fbsence of skln fppendfges
fcquled leslon
esulL of LfumfLlc lmplfnLfLlon
of eplLh lnLo deepe Llssue
8fnchlfl cysLs [ phfyngefl pouches

Mf[olLy occu deep Lo
sLenomfsLold
fnL bode fL leel of fngle of
mfnd

unusufl leslon Alse ln floo of mouLh

Llned by sLfLlfled sq eplLh

Wfll conLfln wellogfnlzed lymphold L
gemlnfl cenLe ln wfll

ueelopmenLfl olgln

unceLfln pfLhogenesls

Sfllfy olgln becomes enLfpped by
lymphold L

?ellowlsh colo
ueled fom esldue of embyonlc
Lhyoglossfl ducL

lnLfofl cysL mldllne of Longue [ floo
of mouLh (ey fe)

MosL Lhyoglossfl ducL flse ln eglon of
hyold bone

1efLmenL should be fggessle!



et|o|ogy

lf ln mldllne deelopmenLfl olgln

lf oLhe locfLlon LfumfLlc olgln

1on ducL be seen unnlng lnLo leslon

L1LN1ICN ,UCCCLLLS
Mucous lnslde ducL no suoundlng
chonlc lnflfmmfLoy xn

Sfllfy conLfln lnslde ducL

9L 30 ys old

nee found ln lowe llp

ueled fom cysLlc dllfLfLlon of ducL

Llned by eplLh of ducLfl Lype

unknown pfLhogenesls

8flloonlng of pfLlflly obsLucLed ducL

SponLfneous cysLlc chfnge

NUL
8lulsh colo (fllled wlLh fluld)

Swelllng of floo of mouLh

8esemble fog's belly

x pfLhologlcfl dlfgnosls

Mucous exLffsfLlon cysLs

xLend Lhough mylohyold muscle

9esenL ln submfndlbulf fef [ neck

8efeed Lo cllnlcflly fs p|ung|ng ranu|a