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GENERIC NAME/ BRAND NAME/ DOSAGE

DRUG CLASSES Beta- blocker

THERAPEUTIC INDICATION ACTION Competitively blocks betaadrenergic decreasing the influence of sympathetic nervous system on these tissues, the exitability of the heart, cardiac workload,and oxygen consumption . Hypertension

CONTRAINDICATION AND CAUTIONS History of bronchial asthma or bronchospasm, hypersensitivity, bradycardia, cardiogenic shock, hypotension, metabolic acidosis, after prolonged fasting, severe peripheral arterial circulatory disturbsnces, second or third degree

SIDEEFFECTS

ADVERSE EFFECTS

NURSING CONSIDERATION

Sleep Disturbanc Fatigue loss of appetite mood changes Dizziness visual disturbance Hallucination

Propranolol (Inderal) 10mg/tab P.O. consumption TID (Home Med.)

(GI): gastric pain, flatulence, constipation, diarrhea, nausea, vomiting, anorexia, ischemic colitis, and renal mesentaric arterial thrombosis, retroperitoneal fibrosis, hepatomegaly, acute pancreatitis. (GU): impotence, decrease libido, peyronies disease, dysuria, nocturia, frequency

. If you have diabetes, the normal signs of hypoglycemia (tachycardia) may be blocked by this drug : monitor your blood urine glucose carefully; eat regular meals, and take your diabetis madications regularly. . report difficulty breathing, night cough, swelling of extemities, slow pulse, confusion, depression, rash, fever, sore throat.

Drug name

Drug classes

Therapeutic actions

Indications

Contraindications/cautions

Side effects blurred vision, persistent or severe headache, rash, more frequent or more severe angina attacks, fainting.

Adverse effects

Nursing consideration

Acute angina Nitroglycerin ( Nitrostat) Patch 1mg OD (Hospital Med.) (Home Med.) Antianginal agent Nitrate Relaxes vascular smooth muscle with a resultant decrease in venous return and decrease in arterial BP, which reduces left ventricular workload and decreases myocardial oxygen consumption.

Contraindications: allergy to nitrates, severe anemia, early MI, head trauma, cerebral hemorrhage, hypertrophic cardiomyopathy, pregnancy, lactation. Use cautiously with hepatic or renal disease, hypotension or hypovolemia, increased intracranial pressure, constrictive pericarditis, pericardial tamponade, low ventricular filling pressure or low PCWP.

CNS: Headache, apprehension, restlessness, weakness, vertigo, dizziness, faintness CV: Tachycardia, retrosternal discomfort, palpitations, hypotension, syncope, collapse, orthostatic hypotension, angina Dermatologic: Rash, exfoliative dermatitis, cutaneous vasodilation with flushing, pallor, perspiration, cold sweat, contactdermatitis transdermal preparations, topical allergic reactions topical nitroglycerin ointment GI: Nausea, vomiting, incontinence of urine and feces, abdominal pain Local: Local burning sensation at the point of dissolution (sublingual)

To use transdermal systems, you may need to shave an area for application. Apply to a slightly different area each day. Use care if changing brands; each system has a different concentration.

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