Ofloxacin

Generic Name

Brand Name Drug Classification Ordered Dose Indications

Floxin, Ocuflox Antibiotic, Fluoroquinolone 30 mg q12 Lower respiratory tract infections caused by Haemophilus influenzae, Streptococcus pneumoniae Acute, uncomplicated urethral and cervical gonorrhea due to Neisseria gonorrhoeae, nongonococcal urethritis, and cervicitis due to Chlamydia trachomatis, mixed infections due to both

Uncomplicated skin and soft tissue infections due to Staphylococcus

aureus, Streptococcus pyogenes, Proteus mirabilis Uncomplicated UTIs Prostatitis due to E. coli Contraindications Contraindicated with allergy to fluoroquinolones, lactation Use cautiously with renal impairment, seizures, pregnancy CNS: Headache, dizziness, insomnia, fatigue, somnolence, depression, blurred vision Adverse Effects GI: Nausea, vomiting, dry mouth, diarrhea, abdominal pain Hematologic: Elevated BUN, AST, ALT, serum creatinine and alkaline phosphatase; decreased WBC count, neutrophil count, Hct Other: Fever, rash, photosensitivity Nursing Responsibilities Assess clients allergy to fluoroquinones, renal impairment, seizures, lactation, pregnancy Assess patients skin color, lesions; T; orientation, reflexes; mucous membranes, bowel sounds; LFTs, renal function tests Arrange for culture and sensitivity tests before beginning therapy Continue therapy for 2 days after the signs of infection have disappeared Administer oral drug 1 hr before or 2 hr after meals with a glass of water

 Ensure that patient is well hydrated Administer antacids at least 2 hr before or after dosing Monitor clinical response; if no improvement is seen or a relapse occurs, repeat culture and sensitivity tests Instruct client to take drug on an empty stomach, 1 hr before or 2 hrs after meals. If an antacid is needed, do not take it within 2 hrs of ofloxacin dose Use eye or ear drops as instructed; keep tip away from surfaces; wash hands before administering Drink plenty of foods Avoid prolonged exposure to sunlight Inform patient that he may experience side effects like nausea, vomiting, abdominal pain (eat frequent small meals); diarrhea or constipation; drowsiness blurring of vision, dizziness Instruct to report rash, visual changes, severe GI problems, weakness, tremors