8 June 2011 MARIA EUFEMIA YAP Associate Dean Ateneo School of Medicine and Public Health Sitio Puting

Bato Brgy Inarawan Antipolo City

RE: Vaccine Preventable Diseases (Except Influenza) Dear Dr. Yap: Greetings of good health! ActiveOne Health, Inc. would like to inform your good office that it is currently participating in the disease awareness campaign of the Department of Health (DOH) for the prevention of Measles, Tetanus, Diphtheria, Polio, Pertussis, Typhoid Fever and Salmonellosis, Rabies, Pneumonia, Cervical Cancer and Hepatitis A and B and their complications. In this relation we are very pleased to present to you our proposal for your vaccine requirement for the year 2011. The following is our price offer and stocks availability protection which shall be valid up to June 30, 2011: We shall also provide the following as part of the Vaccination Program: 1. Disease-awareness and campaign programs on the different programs 2. Educational print-outs, leaflets and flyers, Posters, Videos 3. Support materials on the scheduled vaccination day such as: - Alcohol, cotton and syringes - Vaccination reminder cards 4. Vaccination monitoring & health recording Limitations: - Vaccines are highly perishable in nature such that No return, No exchange Policy shall apply. - Vaccines Country Prescribing Information is available upon request. Please feel free to call Derick Custodio at the numbers mentioned below or the following mobile number 0920-9509075 for any other inquiries and we shall be very glad to accommodate you. Very truly yours,

(Signed) TONY S. CASTILLO Director

ActiveOne Health Inc. 9th Floor 88 Corporate Center, 141 Sedeno corner Valero Streets, Salcedo Village, Makati City Tel: (+632) 893.2925/ 817.7372/ 856.7939 to 40 www.activeonehealth.com - 1 Vaccine Preventable Diseases Ateneo School of Medicine ActiveOne Health, Inc. 8 June 2011)

ADDITIONAL DETAILS AND RATE SCHEDULE

A. Hepatitis A & B Vaccines - for the prevention of Hepatitis A and B.

Brand Name Havrix

Vaccine Type Inactivated Hepatitis-A

Price/ Vial

Dosage

Engerix Twinrix (Adult)

rDNA Hepatitis-B 20mcg/mL Vaccine Combined Hepatitis A & B Vaccine B- Recombinant A-Inactivated

Php 2,200.00 0, 2nd months for Adult and Children Booster: Child (12mos-18yo) 612mos after; Adult 6-12mos apart Php 630.00 0, 1st month, 6th month for Adult Php 2,000.00 0, 1st month, 6th month for Adult (out of stock)

B. Cervical Cancer Vaccine - for the prevention of cervical cancer.

Brand Name Cervarix

Vaccine Type Human Papilloma Virus types 16 and 18

Price/ Vial

Dosage

Php 1,850.00 0, 1st month, 6th month for females over 10years of age and above Php3,500.00 0, 2nd month, 6th month for females over 6years of age and above

Gardasil

Human Papilloma Virus types 6, 11, 16 and 18

- 2 Vaccine Preventable Diseases Ateneo School of Medicine ActiveOne Health, Inc. 8 June 2011)

C. Pneumoccocal Vaccine- for the prevention of pneumonia.

Brand Name Pneumo 23

Vaccine Type Purified capsular polysaccharides of Strep pneumoniae Purified capsular polysaccharides of Strep pneumoniae

Price/ Vial

Dosage

Php 900.00 Primary immunization: single dose 0.5ml, Re-immunization: Once every 5 years for high risk subjects Php 800.00 Primary immunization: single dose 0.5ml, Re-immunization: Once every 5 years for high risk subjects

Pneumovax 23 (MSD)

D. Typhoid Vaccine- for the prevention of Typhoid fever and Salmonellosis.

Brand Name Typherix

Vaccine Type Vi polysaccharide Typhoid

Price/ Vial

Dosage

Php 825.00 Primary immunization: single dose 0.5ml

E. Measles, Mumps and Rubella Vaccine for the prevention of Measles, Mumps and Rubella

Brand Name Priorix

Vaccine Type Live Attenuated Measles Mumps Rubella Vaccine

Price/ Vial

Dosage

Php 680.00 single dose

F. Varicella Vaccine for the prevention of Chickenpox

Brand Name Varilrix

Vaccine Type Live Attenuated Varicella Vaccine

Price/ Vial Php 2,145.00

Dosage Single dose at 0.5 ml for 9mos. 12y/o

Okavax

Live Attenuated Varicella Vaccine

13y/o > 0, 6 weeks 0.5ml Php 2,050.00 Single dose at 0.5 ml for 9mos. 12y/o 13y/o > 0, 6 weeks 0.5ml
- 3 Vaccine Preventable Diseases Ateneo School of Medicine ActiveOne Health, Inc. 8 June 2011)

G. Diphtheria, Pertussis and Tetanus Toxoids- for the prevention of Diphtheria, Pertussis and Tetanus

Brand Name Adacel

Vaccine Type Adsorbed Tetanus and diphtheria toxoids combined with component Pertussis vaccine

Price/ Vial

Dosage

Php 1,925.00 Single dose at 0.5 ml

H. Storage Requirement (for all above vaccines) Refrigerate between 2-8*C(36*F 46*F). Do not freeze; discard product if frozen Protect from light

- 4 Vaccine Preventable Diseases Ateneo School of Medicine ActiveOne Health, Inc. 8 June 2011)