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Omega-3 Fatty Acids: Here Fishy, Fishy!

Tom Grill/Iconica/Getty Images Salmon is delicious and good for you. To function at its very best, the brain needs fat and sugar. That may sound surprising, given how often we're warned away from those two substances. However, the brain is the only organ that draws nearly all its energy from glucose. It's also the body's second-highest deposit of fat, after fatty tissue itself (such as the butt and the gut) [source: Aaronson]. It's not just any fat and sugar that the brain is after, though. Trans fats and saturated fats, such as those found in fast food and junk food, can decrease cognitive ability [source: UCLA]. One study found that rodents who were given the equivalent of rat junk food couldn't navigate mazes or remember the solutions to problems they'd solved previously [source: Douglas et al.]. Those kinds of fats harden brain cells. Your brain cells crave polyunsaturated fatty acids, which you may know by the names omega6 and omega-3. We typically get enough omega-6 acids throughout the day thanks to their presence in soy and corn oils, but most people need to consume more omega-3 fatty acids. These acids appear to strengthen the brain's synapses, which provide the pathways for neural communication. Omega-3s also appear to help molecules on the synapses directly related to learning and memory. In an Australian study, children who drank a beverage with omega-3 fatty acids received higher scores on tests of verbal intelligence and memory compared to children who didn't have the drink; results were evident after just six months [source: UCLA]. Brain Foods For Babies The benefits of omega-3 fatty acids begin long before birth. A Harvard study found that when women ate fish during the second trimesters of their pregnancies, their infants did better on

cognitive tests at just six months old [source: O'Connor]. Pregnant women, should, however, eat fish with low mercury levels. Additionally, breast milk is a wonderful source of good fatty acids. In 2008, researchers from McGill University found that breastfed children had higher IQs and better academic performance [source: McGill University]. Though babies are tiny, three-quarters of an infant's energy is directed toward the brain [source: Binns]. So drink up, babies! Omega-3 fatty acids are found in some nuts, such as walnuts and hazelnuts, flaxseed, kiwi and most importantly, fish. Researchers aren't sure why exactly fish are so helpful to brain cells, but there's plenty of evidence showing that it might be the ultimate brain food. In one study, elderly people who ate fish at least once a week slowed cognitive decline about 10 percent compared to those who didn't chow down on fish, and the fish-eaters also performed better on tests of memory and mental sharpness [sources: O'Connor, Bakalar]. In rodents, omega-3 deficiency has led to learning impairments, while the consequences of a deficiency in humans include brain disorders such as dyslexia and schizophrenia [source: UCLA]. One physiologist even speculated that fish consumption by early man is what spurred the human brain to get so big in the first place [source: Binns]. To read about the sugar your brain needs and to learn whether too much brain food is a bad thing, swim on over to the next page.

More Brain Food: Glucose and Antioxidants


We mentioned on the last page that your brain needs glucose to function properly. The glucose supply should be steady, so that means no skipping meals. It also means you should avoid a cheap source of glucose, like a candy bar. Candy will give you a quick high and a plummeting low in terms of glucose levels, and if you've ever experienced a sugar crash, you know what that can do to your body. To provide a steady stream of glucose, you should look for food that slowly releases carbohydrates into the bloodstream, which include most fruits and vegetables, milk and breads with lots of grains. Foods such as candy and white bread just give you the sugar rush.

iStockphoto.com/Darren Fisher Breakfast of champions: the slow-burning glucose of oatmeal with the antioxidant power of berries. Glucose is essential for keeping the neurotransmitters in the brain at peak levels, but is there anything else you can eat besides oatmeal and salmon? Yogurt also aids the production of neurotransmitters thanks to its amino acids [source: Douglas et al.]. Choline, a nutrient found in eggs and soybeans, produces a neurotransmitter called acetylcholine; abnormally low levels of acetylcholine have been found in people with Alzheimer's disease, so you know you want to keep yours up [source: Aaronson]. Folic acid, essential for brain function, can be found in spinach and orange juice. And don't be afraid of spicing it up a bit; curcumin, a spice used in curries, may be one reason why India has such a low incidence of Alzheimer's [source: UCLA]. But don't go too crazy with all these brain foods. When you consume too many calories, you can undo the positive brain effects. In the process of converting glucose to energy, extra oxygen is created as unstable molecules called free radicals. Free radicals in turn cause oxidative stress by destroying brain cells they come in contact with. Not only does this oxidative stress force the brain's synapses to work harder, it's also a major factor in many diseases, which is why you so often hear about the benefits of antioxidants. Fruits and vegetables are full of the antioxidants that can fight those free radicals. Load up on a salad of spinach, broccoli, carrots and onions, and don't forget to throw some berries on top. If you're more in the mood for a beverage, you can drink your antioxidants in the form of concord grape juice, which has the total antioxidant level of any fruit, vegetable or juice tested [source: Flora]. Green tea also provides antioxidants to the brain. Keeping your brain running smoothly by means of fueling it with the right energy is just one step to increasing your smarts, though. Eating the right food will clear the pathways for knowledge to zoom around the brain, but you'll have to put it there. For some true food for thought, go to the next page and load up on more information about the brain.

We like to think that men and women are fundamentally the same, excepting their reproductive organs. We all want the same rights and opportunities, and for some things, such as women's suffrage, it was a long, hard fight to achieve equal footing. As a result, we're often appalled at stereotypical suggestions that the sexes might be different. Witness the reaction to the Barbie doll who said "Math class is tough!" in 1992. In 2005, there was controversy surrounding Harvard president Lawrence Summers when he suggested there were innate reasons for why women did not perform as well as men on tests of math and science. Men, on the other hand, have staged massive protests over any silver screen depiction that paints them as merely beerswilling, football-watching couch potatoes with the vocabulary of cavemen. OK, so we invented that last example, but just because we can't track down a concrete example of such a protest doesn't mean that men aren't the tiniest bit irked. Still, we do seem to realize that as much as we'd like everything to be equal between men and women, there are differences in how we go about things. The sales of glossy magazines that promise to teach you how to work with someone of the opposite gender as well as self-help books along the lines of "Men are from Mars, Women are from Venus" are proof that we need a little help understanding what's going on inside the heads of men and women. Next Up
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Why are people's brains different sizes? Brain Quiz Curiosity Project: Do men or women lie more?

As it turns out, it may be better to turn to neuroscience rather than to Cosmopolitan magazine to figure out what's going on inside that guy's brain. Research indicates that men and women do in fact have different structures and wiring in the brain, and men and women may also use their brains differently. In some cases, this may explain some of the stereotypes that we may not like to acknowledge about the genders. For example, men do score better at tasks that involve orienting objects in space, while women do better at language tests [source: Kolata]. From there, it's but a quick jump to the conclusions that men are better at reading maps and women talk too much. It's these kinds of stereotypes that make some people nervous about the findings on the male and female brain -- what kinds of implications would this have for our world? Would women immediately be banned from math classes and would men be forced to become engineers? Before we start jumping to conclusions, go to the next page and we'll take a look at just what sorts of brain differences we're dealing with.

Differences in Male and Female Brain Structure


Scientists have known for a while now that men and women have slightly different brains, but they thought the changes were limited to the hypothalamus, the part of the brain that controls sex drive and food intake. A few scientists may have admitted that men's brains were indeed bigger, but they would have tried to qualify this finding by telling you that it was because men were bigger. Because brain size has been linked with intelligence, it's very tricky to go around saying that men have bigger brains. Yet men do seem to have women beat here; even when accounting for height and weight differences, men have slightly bigger brains. Does this mean they're smarter? Let's keep going. In 2001, researchers from Harvard found that certain parts of the brain were differently sized in males and females, which may help balance out the overall size difference. The study found that parts of the frontal lobe, responsible for problem-solving and decision-making, and the limbic cortex, responsible for regulating emotions, were larger in women [source: Hoag]. In men, the parietal cortex, which is involved in space perception, and the amygdala, which regulates sexual and social behavior, were larger [source: Hoag].

Jamie Grill/IGetty Images Their brains may be different, but they'll likely reach the same conclusion.

Men also have approximately 6.5 times more gray matter in the brain than women, but before the heads of all the men out there start to swell, listen to this: Women have about 10 times more

white matter than men do [source: Carey]. This difference may account for differences in how men and women think. Men seem to think with their gray matter, which is full of active neurons. Women think with the white matter, which consists more of connections between the neurons. In this way, a woman's brain is a bit more complicated in setup, but those connections may allow a woman's brain to work faster than a man's [source: Hotz]. If you're a lady still concerned about the size issues brought up in the first paragraph, let's address that now. In women's brains, the neurons are packed in tightly, so that they're closer together. This proximity, in conjunction with speedy connections facilitated by the white matter, is another reason why women's brains work faster. Some women even have as many as 12 percent more neurons than men do [source: Hotz]. In studying women's brains, psychologist Sandra Witelson found that those neurons were most densely crowded on certain layers of the cortex, namely the ones responsible for signals coming in and out of the brain. This, Witelson believed, may be one reason why women tend to score higher on tests that involve language and communication, and she came to believe that these differences were present from birth [source: Hotz]. But the density of women's neurons, much like the size of a guy's brain, isn't any sort of magic bullet for predicting intelligence. Scientists know this because they've conducted imaging studies on how men and women think. As we've said, men use gray matter, and women use white, but they're also accessing different sections of the brain for the same task. In one study, men and women were asked to sound out different words. Men relied on just one small area on the left side of the brain to complete the task, while the majority of women used areas in both sides of the brain [source: Kolata]. However, both men and women sounded out the words equally well, indicating that there is more than one way for the brain to arrive at the same result. For example, while women get stuck with a bad reputation for reading maps, it may just be that they orient to landmarks differently. And as for intelligence, average IQ scores are the same for both men and women [source: Crenson]. But do we get to these IQ scores through nature or nurture? On the next page, we'll examine whether these different brain structures are set at birth, or whether they're shaped by the environment.

Brain Structure vs. Environment


There may be subtle differences in how even the most equality-minded among us treat baby girls versus baby boys. Girls may be dressed in pink and given dolls, while boys wear blue jumpers and push around trucks. To some people, these environmental factors are impossible to ignore

when considering the human brain. If there are differences in people's brains, it might be due to how society has shaped a person, with neurons and synapses pruned away as the brain deemed them unnecessary. Sandra Witelson, the psychologist mentioned on the previous page, disagrees with that environmental assessment, and she uses an unlikely source to support her belief that our brains are structured at birth: Albert Einstein. Witelson had the opportunity to study pieces of Einstein's brain, and she found its unique structure to be a sort of confirmation that some brain differences simply can't be explained away with social or environmental reasons [source: Hotz]. She didn't look at Einstein's intelligence or accomplishments, but she simply observed that he had a unique brain structure that was likely already formed at birth. This may help to explain why we don't have many Einsteins running around. And when it comes to the stereotype of women underperforming at Einstein's favored subjects of physics and math, that may just come down to slight differences in the brain as well. It may be that girls' and boys' brains develop at different rates. Our educational system, however, doesn't take that into account. When a child encounters a subject that his or her brain is not ready to tackle yet, the child may become frustrated and give up too quickly [source: Ripley].

Jose Luis Pelaez/Getty Images A girl may get uncomfortable if she's the only one in math class.

To tease this out a bit further, girls may start to discern that boys do better in math classes, and that girls in their peer groups are electing not to take more advanced versions of the subjects. This can cause further drops in female enrollment in math and physics courses: One study showed that female students with math, science and engineering majors were uninterested in attending a summer math and sciences conference after they were shown videos in which the gender ratio was unbalanced, with three males for every one female [source: Bryner].

However, another study demonstrated that this sort of insecurity is all in our heads. In that study, girls' math scores improved when they were told that the exam was gender-neutral, while white men's scores on the same test dropped when they were told the scores would be evaluated against Asian men's scores [source: Crenson]. This seems to suggest that we can easily overcome any biological differences, or we can just as easily doom ourselves to fulfilling these prophecies. But at this point, instead of wondering whether we need to revamp the educational system or worry about whether a different brain could become grounds for not hiring someone, it may be more important to focus on how knowing about these differences could help us. Most research for new medications is conducted on male volunteers and male animals exclusively, because it was believed that the female brain would show wildly erratic results during various phases of the menstrual cycle [source: Hoag]. Knowing about the differences in male and female brains could open up tremendous opportunity in diagnosing and treating brain disorders. For example, depression and chronic anxiety are diagnosed far more often in women; this may have to do with differences in the chemical composition of the brain, as one study has shown that women produce only about half as much serotonin (a neurotransmitter linked to depression) as men and have fewer transporters to recycle it [source: Karolinska Institutet]. Or, it may have to do with how the various sides of the female brain respond to emotions and pain. Men, on the other hand, are more likely to be diagnosed with autism, Tourette's syndrome, dyslexia and schizophrenia, to name a few [source: Hoag]. Additionally, disorders like schizophrenia and Alzheimer's disease can show up differently in men and women [source: Society for Women's Health Research]. Based on the location of neurons, brain injuries may affect men and women differently [source: Carey]. This sort of knowledge could affect drug treatments, or at least explain why some drugs work differently in men and women. It extends beyond just drugs, though. One study has found that men and women's brains fire differently when they do plan a visually guided action, like reaching for an object. This may necessitate changes in physical therapy after a brain disorder that affects one side of the brain, like a stroke [source: York University]. Scientists have more work to do in learning about the human brain. If you'd like to learn more about the brain, gender and related topics, visit the links on the next page.

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