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anterior posterior
Adeno-
hypophysis:
- Pars Neurohypophysis:
tuberalis
- Median
- Pars eminence
intermedia
- Infundibulum
- Pars
distalis - Pars nervosa
Slide 67, hypophysis
Plane of cutting:
horizontal
Slide 67, hypophysis, H&E, 4x
Neurohypophysis:
pars nervosa
Adenohypophysis:
pars intermedia
Adenohypophysis:
pars distalis
Slide 67, hypophysis pars nervosa, H&E, 40x
endothelial
cell
capillaries
(fenestrated
endothelium)
pituicytes
axons
(hypothalamo-
hypophyseal tract)
Slide 67, hypophysis pars intermedia, H&E, 40x
chromophil
Staining chromo-
(H&E) phobe
acidophil basophil
Cell type 1 2 1 2 1 2
Hormone ACTH
GH LTH TSH LH FSH IL-6
secreted MSH
Slide 67, hypophysis pars distalis, H&E, 40x
chromophobe cell
basophil cells
acidophil cells
To identify the parts of the hypophysis
and the structures listed:
Magnocellular nuclei:
Hormone secreted:
oxytocin, vasopressin
Axon terminals:
pars nervosa Parvocellular nuclei:
E.g.: Hormone secreted:
nucl. paraventricularis releasing / inhibiting
nucl. supraopticus hormones
(pl. CRF, TRH)
Axon terminals:
infundibulum
E.g.:
nucl. arcuatus
Slide 85, hypothalamus:
magnocellular nuclei
cerebellum
Cortex cerebri
brainstem
Plane of
cutting:
frontal
nucl. paraventricularis
Staining method:
nucl. supraopticus hypothalamus
oxytocin immunocyto-
chemistry
Slide 85, hypothalamus, oxytocin immunocytochemistry, 4x
nucl. paraventricularis
axons
(hypothalamo-
hypophyseal tract)
3rd
ventricle
optic tract
nucl. supraopticus
Slide 85, nucl. supraopticus, oxytocin immunocytochemistry, 40x
To identify the magnocellular nuclei of the
hypothalamus
The histology of the thyroid gland
Follicles:
Follicular epithelium:
- simple cuboidal
- follicular epithelial
cells (thyreocytes)
-Microvilli on the apical
surface
- endodermal origin
- triiodothyronine (T3) /
Parafollicular (C) cells: thyroxin (T4)
- Between the follicles,
capillaries bellow the follicular cells
- Ectodermal origin
- calcitonin
Slide 68, thyroid gland, H&E, 4x
follicles
follicular
follicle epithelial
cells
colloid
(thyroglobulin)
capillary
The synthesis of hormones by the follicular cells
The synthesis of thyroglobulin
colloid Synthesis colloid pinocytosis
Colloid pinocytosis