PRO ARGI-9

PRO ARGI-9 is the KEY CODE to TURNING ON

YOUR BODY’S “METABOLIC SWITCH”

PRO ARGI-9
PROTOCOLS
Daytime
Night-Time
Fat-Burning
Athletes
PRO ARGI-9 IS BACKED BY A REGISTERED
FEDERAL GOVERNMENT PATENT and
TWO DECADES OF L-ARGININE RESEARCH
Copyright 2006

L-ARGININE
The amino acid L-arginine is considered the most potent
Nutraceutical ever discovered, due to its powerful health
properties, and is referred to by scientists as the “Miracle
Molecule.”

The remarkable properties of L-arginine were validated by the

1998 Nobel Prize in Medicine, and since then have created a
frenzy of interest in the Pharmaceutical and Nutraceutical fields.

Columbia University refers to L-arginine as the “Magic Bullet” in

human health. Over 10,000 L-arginine citations have been
compiled by Columbia University researchers in their quest to
document the benefits of this simple amino acid. It is now taught to
medical students at the Columbia University College of Physicians
and Surgeons.

The Nobel Prize landmark discovery of the functions of nitric

oxide (NO) highlighted the fact that without NO, human life would
be impossible. Even more revolutionary was the irrefutable
evidence that L-arginine is the sole NO molecule in the human
body.

Twenty years ago, the idea that a simple and humble amino acid
could change the face of medicine would have been dismissed.
Now, physicians, researchers, and scientists are embracing the
effectiveness of L-arginine and its use has become mainstream.

FORMS OF L-ARGININE:
Creating Safe L-Arginine Formulas
Incorrect ingredients in L-arginine products will block L-arginine’s
entry into the body as a free form amino acid. If L-arginine is not
properly formulated, it will not elevate serum levels of L-arginine,
will not cross the Blood-Brain-Barrier (BBB), and will not provide
health benefits. L-arginine products that are founded on metabolic
mistakes do not metabolize correctly, and are therefore ineffective.

It is unwise to use any L-arginine product without first ascertaining

its Length of Use (history and use in humans), the formulator of
the product, the Patent-status, the form of L-arginine used, the
exclusion of L-arginine antagonists, and its ultimate Isoform
Pathway via inclusion of a “Blind Amino Acid Rider.”

It is mandatory that the form of L-arginine be bound to a Blind

Amino Acid Rider, and formulated by an L-arginine expert with a
background in safe arginine Isoform Pathways.

The L-arginine-nitric-oxide signaling pathway is probably the most

complicated facet of biochemistry. In creating an efficacious
formula, the form of L-arginine used will dictate the quality of the
product. If the form of arginine used in a formula is not
appropriate, the product will not work, and can exhibit side effects.

The L-form (left-handed) of arginine is acceptable for human use,

while the D-form (right-handed) is not. The D-form of L-arginine
is an example of an unacceptable form of L-arginine, though there
are many other unacceptable forms, including L-Arginine
antagonists.

Antagonists are agents that directly compete with L-arginine and:

• Block L-Arginine health benefits

 • Prevent L-Arginine metabolism
• Negate L-Arginine’s ability to cross the Blood-Brain-Barrier
• Cause potential serious health problems (including damage to
sperm and mortality)

Antagonists are listed below: Unacceptable L-Arginine Formulas

UNACCEPTABLE L-ARGININE FORMULAS

ARGININE HCL
In studies where the HCL form of L-arginine has been used, metabolic
acidosis and alterations in electrolytes have been documented. Not
recommended for human use. Arginine HCL is the form that was used in the
tragic Johns Hopkins/JAMA clinical trial that caused mortalities.
(www.ArginineAnswers.com).

ARGININE PYROGLUTAMATE
Not recommended for human use. Mechanism of action in the body is
entirely speculative according to the Physician’s Desk Reference (PDR).

ARGININE KETOGLUTARATE
and ALPHA-KETOGLUTARATE (AKG)
Researchers and physicians caution that Alpha-ketoglutarate is not
recommended for human use.

HIGH GLYCEMIC L-ARGININE

High glycemic L-arginine formulas are not effective and are contraindicated
for use in humans. High glycemic formulas include those that contain:
maltodextrins, glucose, glucose polymers, sugar (sucrose), honey, high
fructose corn syrup, fructose corn syrup, flavors made with maltodextrins,
sweeteners without caloric impact, and any high glycemic raw material. Any
of these ingredients block arginine transport and metabolism and are
contraindicated in L-arginine formulas.
NUTRIENTS & SUPPLEMENTS
Foods, drinks (other than water), nutrients, vitamins, herbs, minerals, and
supplements also block L-arginine. Therefore, they must be taken separately
from L-arginine formulas. DIRECTIONS for REGIMENS are explained
below, which outline specific timing.

CAPSULES, TABLETS, SPRAYS, LIQUIDS

FORMULAS CONTAINING LESS THAN 5,000 mg for

DAYTIME USE, and LESS THAN 10,000 mg FOR NIGHT-
TIME USE

FORMULAS WITHOUT A BLIND AMINO ACID RIDER

FORMULAS THAT CONTAIN PROTEIN OR ANY

COMPETING AMINO ACID

L-LYSINE
One of the most prominent formulating mistakes related to L-arginine
antagonism is the inclusion of Lysine. L-lysine is a direct antagonist of L-
arginine, though it is frequently seen in L-arginine formulas. L-lysine is
added to L-arginine for the purpose of mitigating the herpes reaction of body
sores (see Herpes Simplex Virus below), as L-arginine can reactivate the
herpes simplex virus (HSV) if it is improperly formulated. Formulas
containing L-arginine with L-lysine do not work, and are the result of
improper formulating. Dietary disproportions of amino acids can alter the
flux of specific amino acids across the Blood-Brain-Barrier (BBB), and the
Lysine/Arginine antagonism is an example of this alteration. A plethora of
clinical studies have proven that L-arginine and L-Lysine are antagonistic.

ASPIRIN
Aspirin is a known antagonist to arginine, and cannot be taken within 2
hours of taking L-Arginine. Aspirin can be beneficial and is frequently
recommended by a physician. If your physician has recommended aspirin,
take it separately from L-arginine.

L-ORNITHINE
L-ornithine has been clinically proven to be an antagonist of L-arginine and
disrupts L-arginine transport. L-ornithine is contraindicated in any L-
arginine formulas, and specifically in products geared to the athlete. L-
ornithine should be avoided by bodybuilders, powerlifters, and all other
athletes, as well as persons desiring to increase muscle mass, because
ornithine is a non-protein amino acid. Ornithine is not anabolic and is not
used to make protein in the human body, whereas arginine does make
protein and is anabolic.

L-CITRULLINE
According to multiple independent studies, L-citrulline is not an appropriate
ingredient in an L-arginine formulation. The use of Citrulline in an L-
arginine formulation can cause inherent problems, including depletion of L-
arginine.
• Endogenous NOS inhibitors reduce the enzyme sensitivity to L-arginine. These
inhibitors include, NG, NG-dimethyl-L-arginine, L-citrulline, argininosuccinic
acid and agmatine.

• Intracellular L-citrulline, an NOS product, is a potent inhibitor of NOS so that the

cells may need extra L-arginine to compete with L-citrulline inhibition.

The Arginine Paradox (Folia Pharmacol. Japan Vol. 119 7-14:2002 Department of
Pharmacology, Teikyo University School of Medicine):

Lee J, Ryu H, Ferrante RJ, Morris SM Jr, Ratan RR. Translational control of inducible nitric
oxide synthase expression by arginine can explain the arginine paradox. Proc Natl Acad Sci U S
A 2003;100:4843-8.

P. Roy. Recent trends in the nitrergic nervous system.2005. In. Journal of Pharmacology; P. Roy,
G. Venkat Ramana, M. Naidu, P. Usha Rani

Thomas G, Ramwell PW. Nitric oxide, donors and inhibitors. In: Bertram G Katzung, editor.
Basic and Clinical Pharmacology. United States: McGraw Hill; 2004.p.313-8.

Chandran S, Sridhar N, Veeranjaneyulu A. Nitric oxide: concepts, current perspectives and

future therapeutic implications. Indian J Pharmacol 1998;30:351-66.

PRO ARGI-9
 TWO DECADES OF L-ARGININE RESEARCH

Pro Argi-9 is an L-arginine formula backed by over 20 years of

research and a registered Patent. Pro Argi-9 is the result of the
entire body of work conducted by Dr. Ann de Wees Allen, with
two-decades of documented safe L-arginine use in humans.

Pro Argi-9 represents the First Generation of safe and effective L-

arginine, as Pro Argi-9 is the first L-arginine product proven to be
safe in humans long-term. Pro Argi-9 is also the only L-arginine
product to be used safely in humans over a 23-year period (since
1983).

PRO ARGI-9 LEGAL CLAIMS

Per FDA and FTC Federal government law, in order to legally

make claims related to any L-arginine product, substantiation
(definitive proof) of said claims is mandatory. It is illegal to make
a “claim” without prior documentation.

“Pro Argi-9 is the only L-arginine product researched

over a 20 + year period with documented substantiation
of long-term safety, efficacy, and proof of claims”

Legal Claims for

PRO ARGI-9
All “Legal Claims” herein stated (1-15) are solely related to the Pro Argi-9
Patent, as awarded to Dr. Ann de Wees Allen, the exclusive inventor and
Patent-holder of Pro Argi-9.

Each of the fifteen (15) claims for Pro Argi-9 have been submitted and
analyzed by FDA and FTC regulatory attorneys and are allowed under the
Dietary Supplement Health and Education Act of 1994.

Said claims have been determined to meet the legal requirements of “Dietary
Supplement Structure/Function” claims per government regulations, as
related to Dr. Allen’s Patent for L-arginine, and upon review of the Patent’s
documentary evidence and clinical substantiation spanning a two-decade
period of more than 23 years, including broad use of safety in humans.

The following claims are unique to the Pro Argi-9 Patent and evidential
documents submitted since 1983, and may not be used for any other product
or patent, under penalty of law.

Basis for Claims:

2 + decades of L-arginine research

Safe use by over 250,000 human subjects

Safe use in humans over a longer period than any other L-arginine
product (since 1983)

Over 100,000 pages of documentation

Only L-arginine that contains a Rider for Blind Amino Acids

Only Certified Low Glycemic L-arginine product

PRO ARGI-9 LEGAL CLAIMS

 Legal Claims as related to L-arginine PRO ARGI-9 Patent :

1. Enhances muscle mass

2. Supports muscle growth
3. Stimulates muscle development
4. Supports hypothalamic response
5. Aids in decreasing body fat
6. Is an antioxidant
7. Helps maintain healthy blood sugar levels
8. Is more well tolerated than L-arginine alone *
9. Helps boost energy
10. Is rejuvenative
11. Helps promote healthy sexual performance
12. Is an adaptogen
13. Growth hormone: Helps provide the building blocks
necessary for the body to maintain its own healthy growth
hormone levels
14. Helps produce Nitric Oxide (NO)
15. Stimulates production of human anti-aging mechanisms in
persons over 23

These claims may be viewed at www.ProArgi9.com

* See explanation at www.ArginineAnswers.com

PRO ARGI-9
Claims & Protocols
The Pro Argi-9 Protocols align the claims (1-15) with the
appropriate method of use.
 CLAIM PROTOCOL
1. ENHANCES MUSCLE MASS: Night-Time

2. SUPPORTS MUSCLE GROWTH: Night-Time

3. STIMULATES MUSCLE DEVELOPMENT: Night-Time

4. SUPPORTS HYPOTHALAMIC RESPONSE: Night-Time

5. AIDS IN DECREASING BODY FAT: Night-Time and

Fat-Burning

6. IS AN ANTIOXIDANT: All Protocols

7. HELPS MAINTAIN HEALTHY BLOOD SUGAR LEVELS:

All Protocols

8. IS MORE WELL TOLERATED THAN L-ARGININE ALONE:

All Protocols

9. HELPS BOOST ENERGY: All Protocols

10. IS REJUVENATIVE: All Protocols

11. HELPS PROMOTE HEALTHY SEXUAL PERFORMANCE:

All Protocols

12. IS AN ADAPTOGEN: All Protocols

13. GROWTH HORMONE: Helps provide the building blocks

necessary for the body to maintain its own healthy growth hormone levels:

Night-Time

14. HELPS PRODUCE NITRIC OXIDE (NO): All Protocols

15. STIMULATES PRODUCTION OF HUMAN ANTI-AGING

MECHANISMS IN PERSONS OVER AGE 23:

Night-Time

PRO ARGI-9
Regimens
Since L-arginine is both Dose-Dependant and Timing-
Dependent, the benefits derived from taking Pro Argi-9 are
based on the amount taken (Dose-Dependent) and the time
it is taken (Timing-Dependent).
Therefore, there are four (4) different PROTOCOLS for
achieving dose-related and time-related benefits from Pro
Argi-9. Each of the four (4) PROTOCOLS is attained by
following a specific REGIMEN as follows:

• DAYTIME

• NIGHT-TIME

• PREFERENTIAL FAT-BURNING

• ATHLETES

DAYTIME PROTOCOL &

REGIMEN
The DAYTIME PROTOCOL is appropriate for:
Claim 6. Antioxidant
Claim 7. Helps maintain healthy blood sugar levels
Claim 8. Is more well tolerated than L-arginine alone
Claim 9. Helps boost energy
Claim 10. Is rejuvenative
Claim 11. Helps promote healthy sexual performance
Claim 12. Is an adaptogen
Claim 14. Helps produce Nitric Oxide (NO)

DIRECTIONS FOR THE DAYTIME REGIMEN

AMOUNT:
One level scoop of Pro Argi-9 contains 5 grams (5,000 mg) of
Elemental L-arginine, the therapeutic dose required for Daytime
use. Use one (1) level scoop of Pro Argi-9 mixed with 8 ounces of
water. Do not use flavored or enhanced water, do not use juice, use
only plain water, either tap water or bottled water.

TIMING: Take 1 scoop (mixed in water) in-between meals. Do

not take with meals or within ½ hour of meals or
snacks. May be taken 1-3 times per day as desired or as
directed by a physician.

CONTRAINDICATIONS: L-arginine products may NOT be used

by persons under age 23 without express instruction from an
attending physician. Pregnant and nursing women may not use any
L-arginine product. Do not take L-arginine with L-Citrulline or any
other amino acid or proteins.
NIGHT-TIME
PROTOCOL & REGIMEN
The NIGHT-TIME PROTOCOL is strictly for use by persons
over age 23 because they have stopped growing (long-bone
growth). You cannot use any L-arginine product at bedtime or
night-time in persons who are under age 23, as they are still
producing growth hormone (GH), and growth factors. Using Pro
Argi-9, or any other L-arginine product to increase height will not
work, as total height is genetically controlled and cannot be
altered.

For persons over age 23, the NIGHT-TIME PROTOCOL is

appropriate for:

Claim 1. Enhances muscle mass

Claim 2. Supports muscle growth
Claim 3. Stimulates muscle development
Claim 4. Supports hypothalamic response
Claim 5. Aids in decreasing body fat
Claim 6. Is an antioxidant
Claim 7. Helps maintain healthy blood sugar levels
Claim 8. Is more well tolerated than L-arginine alone
Claim 9. Helps boost energy
Claim 10. Is rejuvenative
Claim 11. Helps promote healthy sexual performance
Claim 12. Is an adaptogen
Claim 13. Growth hormone: Helps provide the building
blocks necessary for the body to maintain its own
healthy growth hormone levels
Claim 14. Helps produce Nitric Oxide (NO)
Claim 15. Stimulates production of human anti-aging
mechanisms in persons over 23
DIRECTIONS FOR THE NIGHT-TIME REGIMEN

AMOUNT:
Two level scoops of Pro Argi-9 contain 10 grams (10,000 mg) of
Elemental L-arginine, the therapeutic dose required for Night-Time
use. 25 total grams of Pro Argi-9 contain 10 g of pure L-arginine.
Two (2) level scoops of Pro Argi-9 mixed with 8 ounces of water
or any preferred amount of water. Some people wish to use a
smaller amount of water at bedtime to avoid night-time urination.
The amount of water used is not important, as long as the 2 scoops
are mixed thoroughly. Do not pre-mix Pro Argi-9 with water and
let it sit for more than 10 minutes.

Do not use flavored or enhanced water, do not use juice, use only
plain water, either tap water or bottled water.

TIMING: Take 2 scoops (mixed in water) 30 minutes prior to

SLEEP. Example: Dinner 8 PM, take Pro Argi-9 11 PM, go to
sleep at 11:30 PM.

Pro Argi-9 Night-Time Regimen must be taken on an

empty stomach. You cannot eat for 2-3 hours prior to
taking the Night-Time dose, or the product will not
work (accessing the BBB and Delta sleep cycle is mandatory).

Do not take within 2-3 hours of meals or snacks or

drinks other than water. May be taken only one (1) time
per day at bedtime.

CONTRAINDICATIONS: L-arginine products may NOT be used by

persons under age 23 without express instruction from an attending
physician. Pregnant and nursing women may not use any L-arginine product.
Do not take L-arginine with L-Citrulline or any other amino acid or proteins.

PREFERENTIAL
FAT-BURNING PROTOCOL
The FAT-BURNING PROTOCOL is primarily for persons who
wish to use Pro Argi-9 as an adjunct to reducing excess adipose
body fat.

Claim 5. Aids in decreasing body fat

It is also appropriate for:

Claim 6. Is an antioxidant
Claim 8. Is more well tolerated than L-arginine alone
Claim 9. Helps boost energy
Claim 12. Is an adaptogen

MECHANISM FOR PREFERENTIAL FAT-BURNING

When Pro Argi-9 is used as a drink prior to and during exercise, it
triggers a relative shift in substrate utilization from carbohydrate
to FAT.

The biochemical mechanism by which Pro Argi-9 Preferentially

triggers Adipose Tissue Fat-Burning (ATFB) is a result of the
unique combination of Trutina Dulcem bonded to the Elemental
Pro Argi-9 L-arginine molecules in a low glycemic matrix.

No other Arginine product worldwide can produce Preferential Fat

Burning.

Pro Argi-9 taken as a drink prior to and during exercise reduces the
weight of abdominal (retroperitoneal) and epididynal adipose
tissue fat tissues (45 and 25 % respectively).

(Preferential Fat-Burning continued)

Pro Argi-9 increases adipose tissue fat expression of genes aligned

with glucose oxidation and fatty acid oxidation by 120 % to 800 %
via Heme Oxygenase-3, PPARC-1, NOs-1, and AMP-A Protein
Kinase.

An ideal exercise for this mechanism is using a treadmill @ 70 %

VO2max. Alternatively, fast walking or light jogging will also
trigger the appropriate VO2max.

DIRECTIONS FOR
PREFERENTIAL FAT-BURNING REGIMEN

AMOUNT:
One level scoop of Pro Argi-9 contains 5 grams (5,000 mg) of
Elemental L-arginine, the therapeutic dose required for the Fat-
Burning Regimen.

Use one (1) level scoop of Pro Argi-9 mixed with 8-12 ounces of
water.

Do not use flavored or enhanced water, do not use juice, use only
plain water, either tap water or bottled water.

TIMING: Take 1 scoop Pro Argi-9 and mix in 8-12 ounces of

water. You may place 1 scoop in your sports bottle, add water, and
shake to dissolve. Drink the entire contents prior to and during
exercise.

Do not take with meals or within ½ hour of meals or snacks. Do not

use any sports drink within 2 hours of using the Fat-Burning
Regimen – water only.

May be taken 1-2 times per day prior to exercise.

CONTRAINDICATIONS: L-arginine products may NOT be used
by persons under age 23 without express instruction from an
attending physician. Pregnant and nursing women may not use any
L-arginine product. Do not take L-arginine with L-Citrulline or any
other amino acid or proteins.

PROTOCOL for ATHLETES

The PROTOCOL for ATHLETES is designed for the professional,

competing, world-class, and/or serious athlete. Persons under age
23 may not use this Regimen.
This Regimen is designed to increase muscle mass and muscle
mitochondria, increase strength, reduce adipose tissue body fat,
and to shorten recouperation time. Benefits of specific interest to
athletes are bolded.

For persons over age 23, the ATHLETE’S REGIMEN is

appropriate for:

Claim 1. Enhances muscle mass

Claim 2. Supports muscle growth
Claim 3. Stimulates muscle development
Claim 4. Supports hypothalamic response
Claim 5. Aids in decreasing body fat
Claim 6. Is an antioxidant
Claim 7. Helps maintain healthy blood sugar levels
Claim 8. Is more well tolerated than L-arginine alone
Claim 9. Helps boost energy
Claim 10. Is rejuvenative
Claim 11. Helps promote healthy sexual performance
Claim 12. Is an adaptogen
Claim 13. Growth hormone: Helps provide the building
blocks necessary for the body to maintain its
own healthy growth hormone levels
Claim 14. Helps produce Nitric Oxide (NO)
Claim 15. Stimulates production of human anti-aging
mechanisms in persons over 23
DIRECTIONS FOR ATHLETES REGIMEN

Human Maximum Performance

Serious Results for Serious Athletes

Directions for Athletes taking Pro Argi-9 are very precise, and
must be followed to the letter in order to obtain maximum benefits.

After two decades of working with hundreds of World-Class

athletes, our advanced L-Arginine research and Protocol has been
finely-tuned, and is considered the most successful in the entire
sports industry.

Reaching Human Maximum Performance in sports requires that an

athlete maximize his/her genetic and individual physical potential.
This requires working one-on-one with:

• A skilled nutritional/biochemical expert trained in State-of-

the-Art methodologies in sports performance.
• A trainer that is highly skilled in sports physiology.

PERIMETERS DIRECTLY TIED TO ATHLETIC ABILITY:

1) Genetics/Heredity
2) Somatotype
3) Individual Biochemistry
4) Food Program
5) Nutritional Supplementation
6) Age
7) Focus & Drive (Mental/Brain/Physical)
8) Training
9) Performance Hormone Levels

GAINING ‘THE EDGE”

Without an “Edge” the athlete is doomed to mediocrity. The

“Edge” is gained by going beyond the barriers required of normal
persons, and achieving Human Maximum Performance. All of the
nine (9) perimeters outlined above must be addressed in order to
reach Human Maximum Performance. Trial and Error do not work
in the highly competitive field of sports.

The utilization of Pro Argi-9 in a Human Maximum Sports

Performance program addresses # 5) and # 9) of the 9 Perimeters:

1) Genetics
2) Somatotype
3) Individual Biochemistry
4) Food Program
5) Nutritional Supplementation
6) Age
7) Focus & Drive (Mental/Brain/Physical)
8) Training
9) Performance Hormone Levels

PERFORMANCE HORMONE LEVELS

An athlete’s ability to perform is largely dependent on his/her

hormone levels. The most important sports performance hormones
(in males and females) are testosterone and Growth Hormone.

Athletes with genetically low testosterone or Growth Hormone

(GH) levels will not be able to compete at a high level. Sub-
optimal levels of performance hormones result in ultimate failure
in the professional and competitive sports arena.

In humans, the primary function of Performance hormones is to

provide:

• GENERATION OF NATURAL ANABOLIC HORMONES

• INCREASED MUSCLE MASS
 • DECREASED ADIPOSE TISSUE BODY FAT
• INCREASED INTERNAL THERMOGENESIS
• INCREASED STRENGTH & STAMINA
• REDUCED INCIDENCE OF INJURY
• IMPROVED HEALING TIME

Many athletes turn to illegal steroids, and synthetic testosterone

and GH to increase their performance abilities. These drugs are
illegal and dangerous, and reduce lifespan. They are also
unnecessary. There are legal and safe methods for naturally and
legally increasing performance hormones in humans.

Normal humans produce very high amounts of performance

hormones, such as testosterone and GH, during ages 15-18. After
age 23, production of these hormones decrease, and continue to
descend as age progresses. At age 30, the decline begins to affect
sports performance.

Though the brain, via the hypothalamus/pituitary axis, “turns off”

its production of performance hormones as age progresses
(beginning at age 23), this axis can be re-instated in a natural and
legal methodology in humans.

The brain is completely able and capable of re-instating the same

performance hormones as those found in a teen-ager. It requires
precise dosing and timing, and the ability of L-arginine to cross the
Blood-Brain-Barrier (BBB). If L-arginine does not cross the BBB,
there is no re-instation or release of performance hormones.

Therefore, athletes cannot take L-arginine in a form that is

incapable of crossing the Blood-Brain-Barrier (BBB).

FORMS OF L-ARGININE THAT DO NOT CROSS THE

BLOOD-BRAIN-BARRIER
(For complete list see: Unacceptable L-Arginine Formulas)

• Capsules or tablets
• Sprays or liquid
• High Glycemic formulas (any formula that contains glucose,
glucose polymers, sugar, sucrose, maltodextrins, honey)
• Less than 10,000 mg (10 g) of elemental L-arginine
• Formulas without a Blind Amino Acid Rider
• Formula that contain protein or competing amino acids
• Formulas with no/low carbohydrates
• HCL Arginine or
• Formulas taken at incorrect BBB access-times
• Formulas taken with or near food/drink (other than water)
• Formulas that contain high glycemic flavor systems
• L-Lysine: Unlike L-arginine, L-Lysine does not improve whole
muscle strength or size, and is therefore a substandard amino acid for
athletes and persons desiring to increase size and power output from
muscle tissue and muscle mitochondria.

ATHLETES AMOUNT:

In order to elicit any Performance Hormone response from the

brain, including Growth Hormone and Testosterone, a minimum of
10,000 mg (10 grams) is required. Anabolic, anti-aging, and sports
performance benefits only occurs when 10 grams of pure elemental
L-arginine is ingested in a low glycemic format with no competing
proteins, amino acids, maltodextrins, or sugars.

The appropriate dose for most Athletes is 2 scoops of Pro Argi-9.

10 grams of L-arginine = 2 level scoops of Pro Argi-9

2 level scoops of Pro Argi-9 contain 10 grams (10,000 mg) of

Elemental L-arginine. 3 level scoops contain 15 grams (15,000
mg) of Elemental L-arginine. These are the therapeutic doses
required for the Athlete Regimen (2-3 scoops, depending on the
size of the individual).

When mixing Pro Argi-9, do not use flavored or enhanced water,

do not use juice, use only plain water, either tap water or bottled
water. Biochemically speaking, de-ionized water is the best form
of water available (not distilled or spring water).

Selecting Appropriate Serving Size

Athletes can decide how many servings to take depending on

personal goals and overall size. Start by taking 1 serving the first
night and then increase to 2-3 servings, if desired, over a period of
a few days.

See Contraindications for exemptions.

ATHLETES TIMING:

Take Pro Argi-9 30 minutes prior to sleep on a totally empty

stomach. A totally empty stomach means nothing taken but water
2-3 hours prior to taking Pro Argi-9. You must take Pro Argi-9
thirty (30) minutes prior to sleep because L-arginine must cross the
Blood Brain Barrier (BBB) during Delta sleep.

In ATHLETES, if you have anything in your stomach for two

hours prior taking Pro Argi-9, it is not going to work, and will be a
waste of time, money and effort.

Athletes only produce significant amounts of growth hormone

(GH) two times in a 24-hour period:

1) During specific sleep cycles

2) During intense exercise (not aerobics), such as lifting weights
and resistance exercise

Therefore, athletes can take Pro Argi-9 (at GH doses/2+ scoops)

twice per day, while the non-athlete should not.

TIMING for # 1) SLEEP CYCLE

Take 2-3 scoops Pro Argi-9 and mix in ½ - 1 cup water. Use
enough water for the powder to go into solution. If the water is
cold, it may take a minute for solubility.

Take at bedtime (on a totally empty stomach for 2 hours) 30

minutes prior to sleep. Do not pre-mix the product and let it sit for
more than 15 minutes.

Do not take with meals or within ½ hour of meals or snacks. Do

not use any sports drink within 2 hours of using the Athletes
Regimen – water only. Ingesting food, amino acids, or proteins
with or near this product is not in any way harmful, it simply will
negate the benefits.
TIMING for # 2) INTENSE EXERCISE

Athletes may take an optional 1-2 servings 30 minutes prior to

intense exercise on an empty stomach. Intense exercise is defined
as lifting weights or resistance exercise (not aerobic exercise). If
taking Pro Argi-9 30 minutes prior to sleep is problematic, the
athlete may instead utilize TIMING # 2 (Intense Exercise). In
general, athletes should not eat close to bedtime, as it interferes
with the body’s natural cycles and production of anabolic muscle
building.

ATHLETES SUGGESTIONS

If an athlete is not accustomed to taking large doses of L-arginine,

a slow-start program may be acceptable. In persons not
accustomed to taking large doses of L-arginine, soft stools or mild
diarrhea may occur. This is a normal reaction to high-dose L-
arginine. In said cases, reduce the amount taken until normal stools
return.

Start off the first night with one scoop which is 5 grams of L-
arginine.

For 2-3 nights just take one scoop.

Then go up to 2 scoops, which is 10 grams of elemental L-

arginine. Take 10 grams per night at bed time for about 3 weeks to
a month. The body should then be accustomed to large doses of L-
arginine.

INCREASED DOSES

DIRECTIONS for MALE ATHLETES electing to use more than

10 grams of L-arginine at bedtime:
After working up to 10 grams (without diarrhea), athletes may
elect to start taking 15 grams (3 scoops) per night at bed time.

• Stay at 3 scoops for one month.

• Compare the results with those of the 10 gram dose. If the
athlete is getting better results at 10 grams per night versus
15 grams per night, stay at 10 grams per night.

More is not always better - If you’re not getting better results at 15

grams go back to 10 grams.

FEMALE ATHLETES

Female athletes should stay at 10 grams.

CONTRAINDICATIONS: L-arginine products may NOT be used by

persons under age 23 without express instruction from an attending
physician. Pregnant and nursing women may not use any L-arginine
product. Do not take L-arginine with L-Citrulline or any other amino acid or
proteins. Non-athletes should not take more than 10 g L-arginine at one
time.

Copyright 2006

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