CLINICOPATHOLOGICAL STUDY OF DENTIGEROUS CYSTS IN SINGAPORE AND MALAYSIA

Article type: Meeting Abstract Abstract: This was a retrospective study of dentigerous cysts in people from the SingaporeMalaysian region.The purpose of this study was to present the clinicopathologic features of dentigerous cysts in theOriental population and to compare these data with those from other reported studies. Biopsy records from 1981 to 1993 of 119 cases of dentigerous cysts from patients in Malaysia and Singapore showed that 36.1% of patients were female and 63.9% patients were male. Among patients with cysts, 70.5% were Chinese, 23.2% were Malays, 2.7% were Indian and 3.6% were other ethnic groups. The mean age of these patients was 30.2 + 17.3 years with a peak incidence occurring in the second and third decades. The location of the lesions was almost equal to the maxilla (50.9%)and the mandible (49.1%). There was a marked predilection for the posterior mandible (42.7%) followed by the anterior maxilla (38.2%). Histologically, 90.8 % of the cysts were lined by a non-keratinised stratified squamous epithelium. The cyst linings were mainly thin (90.0%) with 38.7%of cases having a mixed thick and thin lining. Mucous metaplasia was observed in 9 (7.6%) cases. Rushton bodies were seen in 3.4% of cases. Cholesterol clefts in the epithelial lining and lumen were found in 16.8% cases while 12.6% of cases exhibited cholesterol clefts in the cyst wall. Other cellular structures within the cyst wall were lymphocytes (66.4%), plasma cells (52.1%),Russell bodies (16.0%) and histiocytes (4.2%). Odontogenic keratocysts were observed in 5.0%of cases. One case of adenomatoid odontogenic tumour was also observed. Epithelial atypia was seen in 9.2% of cases, islands of stratified squamous epithelial cells in 8.4% of cases while onecase showed a combination of these two features. In conclusion, some clinical features seen in this study are similar to that for the Caucasian population such as prevalence in male, peak incidence in the second and third decades and the predilection for the posterior mandible and anterior maxilla. Histopathologically, odontogenic keratocyst and adenomatoid odontogenic tumour were observed in dentigerous cysts. Author Source ISSN DOI Volume Page Year Yeo, J. F. ; Zain, R. B. ; Ti, L. S. ; Zhao, Y. Y. Journal of Dental Research 0022-0345 74 454-454 1995

Keyword: dentigerous cyst; histology,orientals Please Cite As: Yeo JF, Zain RB, Ti LS, Zhao YY. CLINICOPATHOLOGICAL STUDY OF DENTIGEROUS CYSTS IN SINGAPORE AND MALAYSIA. Journal of Dental Research. 1995;74:454-. URL: http://apps.webofknowledge.com Search Web of Science by Accession No :A1995QT08100432 http://www.mjpath.org.my/2007.1/06Clinicopathological.pdf odontogenic keratocyst; adenomatoid odontogenic tumour;