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Surat
Tanprawate,
MD,
FRCPT(T)
Northern
Neuroscience
Center
Chiangmai
University!
www.neurologycoffeecup.com
Outline
approach
to
pa-ent!
Sudden
onset
of
Localiza-on
of
lesion! neurological
deficit! Suspected
stroke!
Stroke
mimicker
Stroke
VS
Stroke
Tumor
mimicker!
Infec-on
!
Stroke type!
Ischemic stroke! Hemorrhagic stroke!
Stroke
subtype
by
Primary
VS
TOAST
Secondary
classifica-on
Hemorrhagic
stroke!
Stroke
mimicker!
Unrecognized
Confusion
state! Syncope
!
seizure!
13%
ini-ally
diagnos-c
stroke
was
stroke
mimicker
Toxic
and
Subdural
hematoma! Tumor
!
metabolic
disorder!
Misdiagnosis
of
stroke:
Lancet,
1982;1:328‐331!
“stroke
localiza.on:
vascular
distribu.on
of
the
ischemic
lesion”!
Anterior
VS
posterior
circula-o
stroke!
Anterior
circula-on
stroke!
Posterior
circula-on
stroke!
Infarc-on
VS
Hemorrhage!
• Some
clues
from
Hx.
And
PE
• ICH
– Coma
on
arrival
– Vomi-ng
– Severe
headache
– Current
warfarin
therapy
– SBP>220
mmHg
– Glucose
level>170
mg/dL
in
non‐diabe-c
pa-ent
Stroke
1981;12:
288‐293
Arch
Intern
Med
1985;145:1800‐1803!
Classifica-on
of
ischemic
stroke
“TOAST
classifica-on”!
1. Large
artery
atherosclerosis
2. Cardioembolism
3. Small
vessel
occlusion
4. Stroke
of
other
determined
e-ology
5. Stroke
of
undetermined
e-ology!
Problem list
Border-zone ischemia
Anterior watershed
Subcortical watershed
Posterior watershed
Anterior Watershed Infarction
Moyamoya-“like” disease = “Puff-Of-Smoke”!
Bilateral occlusion of internal carotid arteries
⇒ Fine collateral arteries
www.neurologycoffeecup.com