BIOCHEMISTRY 302-951 : GENERAL BIOCHEMISTRY COURSE OUTLINE May 2012 Calendar Description BIOC 302 - General Biochemistry (3 credits):

Metabolic reactions of lipids, steroids, amino acids and nucleotides; the biochemistry of replication, transcription and translation. Credit is given for only one of BIOC 300 or 302 or 303. [3-0-1]. Prerequisite: One of BIOL 201, BIOC 202, BIOC 203 and either (a) one of CHEM 204, CHEM 213 or (b) all of CHEM 205, CHEM 233 or (c) all of PHAR 220, CHEM 233.

Instructors:
Dr. Joel Montane Room: TBA E-mail: jmontane@mail.ubc.ca Lectures: May 7, 9, 11, 14, 16, 18, 23 Office hours during lecture period: Mon, Wed, Fri 1-2 pm or by appointment Dr. Robert Maurus (Course Chair) Room 5458 Life Sciences Centre E-mail: maurus@interchange.ubc.ca Lectures: May 28, 30; June 1, 4, 6, 8, 11, 13 Office hours during lecture period Mon, Wed, Fri 1-2 pm or by appointment

Lecture Schedule:
Monday, Wednesday and Friday 10:00 am to 1:00 pm in Centre for Interactive Research on Sustainability (CIRS) 1250-- NO CLASSES May 21 Victoria Day!!! Dr. Montane: May 7, 9, 11, 14, 16, 18, 23 Amino acid metabolism, Fatty acid oxidation and synthesis, Cholesterol synthesis, Lipid transport, Integration of metabolism. Midterm: IN CLASS - Friday May 25 10:00 am [50% for your final grade. This exam covers all material up to and including May 23] Dr. Maurus: May 28, 30; June 1, 4, 6, 8, 11, 13 Topics: Nucleotide metabolism; Genes, Chromosomes, Chromatin structure; DNA replication and repair; PCR, RNA metabolism; Protein synthesis. Final Exam: IN CLASS - June 15 - 10:00 am [50% for your final grade. This exam covers all material from May 28 to June 13]

Problem sets: Problem sets will be posted on the VISTA course page:
note that answers will not be posted for Dr. Mauruss problem sets.

www.vista.ubc.ca.

Please

Textbook:

Recommended text: Lehninger: Principles of Biochemistry (Fifth edition), Worth Publishers, 2008.

Grading: The midterm will be worth 50% of the final grade, and will cover cover Amino Acid
metabolism, Fatty acid oxidation and synthesis, Cholesterol synthesis, Lipid transport, Integration of metabolism (Dr. Montane). The final exam will be worth 50% of the final grade, and will cover Nucleotide metabolism; Genes, Chromosomes, Chromatin structure; DNA replication and repair; PCR, RNA metabolism; Protein synthesis (Dr. Maurus).

Teaching Assistant:
Raymond Socha - email: socharay@gmail.com

Tutorial Dates:
Before Midterm Exam: After Midterm Exam: May 9, 11, 14, 16, 18, 23 May 30; June 1, 4, 6, 8, 11, 13

Tutorial Times and Location:

T01 Mon, Wed, Fri 2-4 pm in Centre for Interactive Research on Sustainability (CIRS) 1250

IMPORTANT NOTICE REGARDING EXAMINATIONS:

All prescribed examinations are mandatory. Students who miss an examination or are unable to complete other tests or graded work because of medical, emotional or other problems have to follow the procedures for requesting Academic Concession [see UBC Calendar]. An inconvenient examination timetable is absolutely not grounds for deferring an examination in Biochemistry 302. Deferred examinations necessitated by health or other considerations that are completely out of the control of the student will be written on a date set by the course chair. The Department will not schedule make-up examinations for any student who does not notify his or her dean and does not provide appropriate documentation within 5 days of the exam in question. Students without appropriate documentation for missing a midterm or final examination will have zero recorded as their mark for that exam.