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You may assume; (1) The patients described below have had a recorded elevated blood pressure recording on three separate occasions. (2) Lifestyle modifications have been optimised. (3) The patient is on no other anti-hypertensive medication. (4) The patient has essential hypertension. (5) The patient has no contra-indications to any of the medications. Please identify your job title General Practitioner Y Hospital Physician Y Specialty____________________
For the following scenarios please choose which class of drug(s) you would prescribe in the following clinical scenario. Please circle as appropriate.
Scenario 1; A 42 year old man who is otherwise well. BP 165/95. ACEinhibitor Alphablocker ARB BetaBlocker Calcium Channel Blocker Diuretic Other
Comment________________________________________________________________ Scenario 2; A 65 year old white obese type II diabetic with hypercholesterolaemia. BP 165/90 ACEinhibitor Alphablocker ARB BetaBlocker Calcium Channel Blocker Diuretic Other
Comment________________________________________________________________ Scenario 3; A 72 year old female with no past medical history. BP 170/85 ACEinhibitor Alphablocker ARB BetaBlocker Calcium Channel Blocker Diuretic Other
Comment________________________________________________
Table 1; Survey response rates from different doctor groups. * GIM General Internal Medicine. Responders comprised Gastroenterology (7), Respiratory medicine (8) and general medicine (15). Number surveyed Response rate Percentage
1082 33 126
13 28 28 57
540 25 73
8 17 18 30
Table 2; Survey results for scenario 1: A 42 year old white man with no past medical history and a blood pressure of 165/95 mmHg.
(N=540)
318 (58.8%) 2 (0.3%) 67 (12.4%) 47 (8.7%) 143 (26.5%) 6 (1.1%)
-BLOCKERS
BETA-BLOCKERS CALCIUM CHANNEL BLOCKERS DIURETICS NONE
Table 3; Proportion of physicians who selected ACE-Inhibitor/Angiotensin Receptor Blocker (ACE/ARB) over all other options in scenario 1.
Number responded Number who selected ACE/ARB Number who did not select ACE/ARB
Probability of choosing ACE/ARB over any other option
(Chi-square)
540 25 73
8 17 18 30
Table 4; Survey results for scenario 2: A 65 year old white obese type II diabetic with hypercholesterolaemia and a blood pressure of 165/90 mmHg. (* One GIM physician answered scenario 1 but did not answer scenarios 2 or 3.)
(N=540)
494 (91.5%) 6 (1.1%) 7 (1.3%) 67 (12.4%) 30 (5.6%) 0 (0%)
-BLOCKERS
BETA-BLOCKERS CALCIUM CHANNEL BLOCKERS DIURETICS NONE
Table 5; Proportion of physicians who selected ACE/ARB over all other options in scenario 2.
Number responded Number who selected ACE/ARB Number who did not select ACE/ARB
Probability of choosing ACE/ARB over any other option
(Chi-square)
540 25 72*
8 17 18 29
(N=540)
50 (9.1%) 3 (0.6%) 11 (2.0%) 135 (25.0%) 361 (66.9%) 3 (0.6%)
-BLOCKERS
BETA-BLOCKERS CALCIUM CHANNEL BLOCKERS DIURETICS NONE
Table 6; Survey results for scenario 3: A 72 year old white female with no past medical history and a blood pressure of 175/80 mmHg. (* One GIM physician answered scenario 1 but did not answer scenarios 2 or 3.)
Table 7; Proportion of physicians who selected Calcium Channel Blocker (CCB)/Diuretic over all other options in scenario 3.
Number responded Number who selected CCB/Diuretic Number who did not select CCB/Diuretic
Probability of choosing CCB/Diuretic over any other option
(Chi-square)
540 25 72*
8
17 18 29