Drug Facts

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1.

#1 COD in males 2544 1 1st gen Cephalorsporins are also known as 2, 7, 9, 10 2mg gum 2nd gen- atypical antipsychotics 4mg gum 25 A1 agonist Abacavir Abacavir (ABC) Acebutolol Acetazolamide (CAI) Acetone Acetylcholine Activated charcoal Acyclovir Adrenal Gland Advair Diskus Albuterol Allopurinol Allopurinol AE

Hepatitis C added to vit d by kidney

30. 31. 32.

Amoxicillin Amphetamine tx Amphetamines Anesthetic triad Angioedema treatment Anticholinergics Antimotility agents

Abx for Otitis Media acidify urine added to anti-depressants for refractory depression hypnosis, analgesia, paralysis Epinephrine Alzheimer's patients should avoid Codeine Diphenoxylate/Atropine Loperamide Acyclovir Valacyclovir Penciclovir Famciclovir 1st line tx for early OA hepatotoxic -artan once you start these drugs you must stay on them forever Alkalization of urine likes acid only ARV that decreases lipids increases bilirubin decreases lipids likes acid BB- unlabeled use for migraine prophylaxis most effective statin FTC + TF + Efavirenz father of all anticholinergics deficient in chronic alcoholics we must get this from out diet SJS Kernicterus 2nd best at lowering LDL, but may increase triglycerides chelates 1st line for insomnia 1 of three treatments for EPS required by Vit D supplements in order to be absorbed

2. 3.

One and dones

33.

4. 5. 6.

Vit K helps form these clotting factors smoking 1-24 cigarettes per day indicated for bipolar mania smoking >24 cigarettes per day added to Vit D by liver should not be taken w/ uncontrolled HTN most potent NRTI most potent NRTI BB w/ ISA tx for altitude sickness metabolite of isopropyl alcohol dopamine has an inverse relationship with sole decontaminate procedure for suppression and tx of HSV-2 Produces hydrocortisone Fluticasone and Salmeterol short acting B2 agonist- rescue agent decreases uric acid synthesis SJS Toxic epidermal necrolysis AHS should be avoided while on MAO-Is DOC for panic attacks Influenza A tx along w/ parkinson's AE: insomnia Gram (+) and some Community acquired gram (-) ((E.Coli, H. Flu, M. Catarr)) AE: Visual disturbances Blue discolor to skin 1st line prophylaxis of migraine if patient is also depressed CCB- great for ptt w/ CHF

34.

35. 36.

7. 8. 9.

37.

Antivirals for Herpes Simplex

10. 11. 12. 13.

38.

APAP ARBs ARV ASA OD treatment Atazanavir

39. 40.

14. 15.

41. 42.

16. 17. 18. 19. 20. 21. 22.

43.

Atazanavir Atenolol Atorvastatin Atripla Atropine B1 (thiamine) B12 (cyanocobalamin) Bactrim AE BAS BAS AE Benadryl Benzotropine Bile/Fat

44.

45. 46. 47. 48. 49.

23. 24. 25.

alpha agonists Alprazolam Amantidine Aminopenicillin

50.

51.

26.

52. 53.

27.

Amiodarone Amitryptiline Amlodipine

54. 55.

28.

29.

56.

Biologic DMARDS

group of drugs which should never be combo'd (shuts down both branches of immune system) Can reactivate TB (do PPD first) Osteonecrosis of jaw 1st line for osteoporosis 1st line treatment for Osteoporosis red hourglass shape dosed w/ L-dopa for hyperprolactinemia and NMS tx inhibiting PDE-4 Violin-shaped venom is potent vasoconstrictor eating disorders people with epilepsy anti-anxiety med that person can still drive BUS Vit D form used in ptts w/ chronic kidney dz active form TCA like DOC for trigeminal neuralgia (peripheral neuropathy) AE: SJS, hepatotoxicity Diuretic to manage Glaucoma BB best for patients w/ CHF C/I in the ingestion of corrosives HIV Cancer Thiopental enzyme converting L-dopa to DA in CNS cross-sensitivity w/ PCN cocaine toxicity

77. 78. 79.

Chlopromazine Chocolate blood Cholecalciferol (D3) Cholinergic Overload happens in: Chronic use of steroids Ciclesonide Cidofovir AE Ciprofloxacin Ciprofloxacin AE Cisapride Clarithromycin Clindamycin Clindamycin Clonazepam CMV treatment Cocaine Colchicine

father of anti-psychotics Cyanide tx result preferred supplemental form of Vitamin D tetanus nerve gas exposure > 20mg or prednisone for >14 days causes HPA suppression most hydrophilic inhaled steroid renal toxicity DOC for anthrax tendon rupture Prokinetic agent related to QT interval prolongation macrolide with AE - metallic taste causes drug-induced C Diff DOC for aspiration pneumonia also used for topically for acne long acting BDZ used for status epilepticus Ganciclovir Foscarnet stimulates alpha-1, beta-1 and beta-2 inhibits leukocyte entry into joints anti-inflammatory (doesn't manage pain) Agranulocytes Aplastic anemia alopecia BAS causing mild decrease in HgBA1C FTC + TF + Rilpivirine long term used of this drug can cause HPA suppression. cherry red or blue treatment for NMS treats: brown recluse bite and leprosy ARV w/ sulfa-moiety to help bloating, edema, CV to help w/ increases appetite and weight gain

80.

57. 58. 59.

Biphosphonate AE Biphosphonates Biphosphonates/Alendronate Black Widow Bromocriptine

81.

82. 83. 84. 85. 86.

60. 61.

62. 63.

bronchial dilation Brown Recluse

87. 88. 89.

64.

Bupropion C/I Buspirone (Buspar) Calcitriol (1,25OHD3)

90.

65.

91.

66.

92.

67.

Carbamezepine

93.

94.

Colchicine AE

68.

Carbonic Anhydrase Inhibitors Carvedilol Cathartics/laxatives Cause Night sweats Causes loss of consciousness central dopa decarboxylase Cephalosporin Cerebrovascular accidents are common manifestation of: Cetirizine

95.

Colesevelam Complera (Btripla) Corticosteroids Cyanide presentation Dantrolene or bromocriptine Dapsone Darunavir decrease estrogen decrease progestin

69.

96. 97.

70.

71.

98. 99.

72. 73.

100.

74. 75.

101. 102. 103.

76.

most sedating of nonsedating anti-histamines

104.

decreased seizure threshold Deferoxamine side effect Diazepam (diastatrectal formula) Dicloxacillin Dicyclomine Didanosine and Stavudine Didansoine and Stavudine AEs Diltiazem Dofetilide Done nomogram Donepezil Dopamine dopamine antagonists Doxycycline Drugs causing angioedema drugs causing hemoptysis Drugs causing Traveler's Diarrhea

excess excitatory NTs (Glutamate), or deficiency in inhibitory NTs (GABA) urine looks pink used for tx of status epilepticus #1 PO for SA anticholinergic for Irritable Bowel Syndrome NRTI's w/ AE of pancreatitis and peripheral neuropathy Peripheral Neuropathy Pancreatitis IV for A. Fib 1st line for persistent A fib used to assess blood levels in ASA overdose 1st line DOC for Alzheimer's action of this drug depends on its dose antipsychotics are most potent tetracycline ASA ACE-I TB Cancer Metronidazole Fluoroquinolones Ciprofloxain Rifaximin abx seizure meds SNRI treats peripheral neuropathy combo'ing NSAIDS only increases risk of AE and doesn't increase efficacy sulfa-moiety anchor drug of Atripla 1st gen NNRTI only ACE-Is available IV a 1st dose phenomenon associated with high potency anti-pscyhotics

128.

Ergots Estrogen

constrict intracranial blood vessels and raise BP Inhibit ovulation, implantation; accelerate ovum transport; induction of luteolygis for chronic insomnia AE- taste disturbance Optic neuritis most commonly removed toxin via dialysis antifreeze calcium oxalate crystals in body fluids under Woods Lamp for recurrent HSV or VZ sildenafil interacts w/ nitrates to cause Buproprion and nicotine patch most tolerable form of iron used for BPH but has secondary use for tx of alopecia Pregnant women should not even handle this drug DOC for C Diff DOC for Addison's DZ lowers seizure threshold reverses benzos can mask S/S of pernicious anemia not activated by thymidine Kinase (TK) Used in resistant cases of HSV1, HSV-2 and CMV Must pre hydrate w/ NS for tx of CMV good for neuropathic pain (diabetics) renally eliminated usually combo'd greasiest topical treatment may increase bioavailability of some statins DOC for tx of increasing isotropy works independently of sympathetic system DOC for increased inotropy

129.

105.

106.

130.

Eszopiclone Ethambutol AE Ethanol ethylene glycol ethylene glycol OD Famciclovir or Penciclovir Fatal hypotension FDA approved combo for smoking cessation Ferrous gluconate Finasteride

107. 108.

131. 132.

109.

133. 134.

110.

135.

111. 112. 113.

136.

137.

114. 115.

138. 139.

116.

117. 118.

140. 141. 142.

Flagyl - Metronidazole Fludrocortisone Flumazanil Folic acid Foscarnet

119.

120.

143.

144.

121.

Drugs interacting with oral contraceptives Duloxetine Duplication therapy

122.

145. 146.

Ganciclovir Gapapentin

123.

124. 125.

Duranavir Efavirenz Enalapril EPS (ExtraPyramidal Side Effects)

147. 148.

Gels Gemfibrozil Glucagon

126. 127.

149.

150.

Glucagon/Atropine

151. 152. 153.

Glucocorticoids Glucocorticoids AE Gout H pylori H1 H2 H2RAs

suppress LTs, PGs, and cytokines thrush chronic disorder w/ high levels of uric acid in blood most common cause of nonNSAID induced ulcer found primarily in the periphery found primarily in the gut AE: confusion, thrombocytopenia, increases risk of pneumonia Renally eliminated -tidine violent or bizarre behavior 1st generation/typical antipsychotic Vit. H snows w/out respiratory depression 1st line diuretic for HTN Ate Blood/Bodily Fluids

178.

Interferon AE

flu depression suicide ideation Used in combo w/ Ribavirin AE: flu, depression, suicidal symp potent anti-inflammatory for OA AE: tendon rupture immediate return to fertility risk of infection absorption is enhanced by coadministration of acid Coronary Steal original antidepressant Hepatotoxic (cannot drink) always supplement pyridoxine (B6) antidote to Unfractionated heparin DOC for River blindness and strongyloidiasis also used to tx scabies Mazzotti-type rxn and opthalmologic rxns only combo PI "the forgiving Protease Inhibitor" BB for HTN urgency/emergency NRTIs that also treat Hep B for ventricle arrhythmias decreases seizure threshold Amyl Nitrite Pearls Sodium Nitrite (IV) Sodium Thiosulfate Needle and tourniquet metallic taste give IV for DVT/PE renally eliminated may cross placenta Phenobarbital Mephobarbital Diuretic w/ risk of hypokalemia, hypocalcemia, hyper urea, and hyperglycemia A generalized seizure has this trait. SSKI minimum alveolar concentration

179.

Interferons Intraarticular Corticosteroids Intrauterine devices Iron Isoflurane AE Isoniazid (INH)

154.

180.

155. 156. 157.

181.

182.

183. 184.

158. 159.

Hallmark PCP toxicity Haloperidol Haloperidol

160.

185. 186.

IV Protamine Ivermectin

161. 162. 163. 164.

HCTZ Hep A-- A is for: Hep B -- B is for: Hep B/C treatment Hep C -- C is for: Hydrocarbons- group 2 Hydroxychloroquine Hydroxyzine Hypothalamus increase estrogen increase progestin or decrease estrogen Increase urinary output (renal) Indanavir AE Indinavir Indomethacin Influenza A antivirals INR and ammonia levels increase

187.

Ivermectin SE Kaletra (Lopinavir/Ritonavir) Kaletra is known as Labetalol Lamivudine and Emtricitabine Lidocaine Lilly Cyanide Antidote Kit

188.

Ribavirin Interferon
189.

165. 166.

Cuts/sex
190.

kerosene/gasoline
191.

167.

used for malaria prophylaxis AE: opthalmic toxicity treats anxiety and is an antipruritic produces CRF to help vasomotor symp (hot flashes) to help w/ dysmenorrhea 2-5 mcg/kg/min of dopamine

192.

168.

193.

169. 170.

194. 195.

lithium SE LMWH (low molecular weight heparin) Long acting barbituate Loop

171.

172.

196.

173. 174. 175. 176.

Kidney stones PI causing kidney stones acute gout attack treatment Amantidine Rimantidine >72 hours of APAP toxic
198. 197.

Loss of consciousness Lugol's Solution MAC

177.

199. 200.

201.

Macrolides Atypicals Magnesium Sulfate Malignant Hyperthermia (MH) MAO-Is example Medication Overuse HA treatment Medrol Dos Pack Memantine Methicillin Methylprednisolone Metoclopramide

Legionella Mycobacterium Chlamydia DOC for Torsades de pontes hallmark = hyperkalemia tx = dantrolene and insulin w/ D5W phenelzine tranylcypromine -Stop medications -Prednisone -DHE for bad neuropathic pain or poison ivy NMDA antagonist Old gold standard for SA IV form of prednisone AE: demargination Prokinetic sensitizes gut to Ach May exacerbate tremor deficiency in iron 1st line oral abx for acne prevents NSAID induced ulcers Used to help induce labor hepatotoxic metabolite of APAP inactivated by glutathione load = 140mg/kg 70mg/kg Q4h x17doses diarrhea Zanamivir Osetlamivir (Tamiflu) raises HDL CCB great anti-HTN AE= gingival hyperplasia Pancuronium

225. 226.

Normal DXA score Not enough cholinergic stimulation: NRTIs Nystatin Opioid triad

>/= -1 Myasthenia gravis block conversion of vRNA to vDNA topical for candida albicans Miosis, respiratory depression, and depressed LOC best sebosuppressive agent characteristic "garliclike" odor Prevents fat absorption. Must co-prescribe Vit A, D, E, K degenerative joint dz most common form of arthritis in US Diuretic working in proximal tubules builds bone destroys/resorbs bone >/+ -2.5 #1 IV for SA Miosis Saliva Slow HR Constrict bronchi Peristalsis and secretion Release of bile Contract bladder do not combo w/ biphosphonates only for severe osteoporosis a back brain problem (cerebellum) valium benzo and halidol Last resort tx for Gout Early Syphillis tx A gram (+) bactericidal this must be used for a regional blockade MAO-Is used to sedate

202. 203.

227.

228.

204.

229.

205.

230.

Oral Retinoid Organophosphates/Pesticides Orlistat

206.

231.

207. 208. 209.

232.

233.

Osetoarthritis (OA)

210.

234.

Osmotic Osteoblast Osteoclast Osteoporosis DXA score Oxacillin Parasympathetic actions

211. 212. 213.

Microcytic anemia Minocycline Misoprostol N-acetyl-p-benzoquinoneimine (N-ABQ) NAC dose in APAP overdose Nelfinavir AE Neuraminidase Inhibitors Niacin Nifedipine

235. 236. 237. 238. 239.

214.

215.

216. 217.

240.

Parathyroid Hormone

218. 219.

241.

Parkinsons PCP treatment

220.

NMB of lethal injection NMS (Neuroleptic Malignant Syndrome)

242.

221.

hallmark = hyperpyrexia associated w/ 1st gen antipsychotics risk of rhabdo cholinergic phenomenon

243. 244. 245.

Pegloticase (Krystexxa) Penicillin G Penicillin V PF Solution (Preservative Free) Phenelzine

222. 223.

Non-allergic rhinitis Nonsteroidal K Sparing Nonsteroidal Potassium Sparing

Diuretic w/ risk of: hyperkalmeia, hypercalcemia, hypo magnesium ineffective in ppl not making aldosterone (addison's dz)

246.

224.

247.

248.

Phenobarbital Phenytoin

drug saved for refractory general seizures AE: rash (SJS), nystagmus, gingival hyperplasia Must give w/ lots of fluids and dilutant (propylene glycol) May compete w/ aspirin most common worm infection in US treatable OTC w/ pyrantel pamoate Telaprevir Boceprevir produces ACTH most potent of all antiplatelets 5-10 mcg/kg/min of dopamine aldosterone hates (excretes) vomiting Most potent acide production inhibitors (permanently inhibit) hepatically eliminated (preferred in renal insufficiency) -prazole for RLS (restless leg syndrome) great for tremor fewest drug interactions (hydrophilic) Triamcinolone Methlprednisolone increases uric acid secretion causes lupus symptoms (butterfly rash on face) drug not activated by swallowing but by cleaver/protease avoid in teens and young adults (acne and osteoporosis) Cervical mucus; Androgenic Mineralocorticoid dopamine hates this for IV ICU sedation soy/egg allergies raises migraine threshold B-adrenergic antagonist

270.

Propylthiouracil (PTU) Protease Inhibitors (PI) Psychosis Pyrazinamide Pyridoxine (B6) QRS prolongation and decreased seizure threshold Raise BP (Alpha-1 agonist) Raloxifene Reversible Acetylcholinesterase inhibitors Rhabdo Rheumatoid Arthritis (RA) Rhinovirus Ribavirin

249.

most potent tx for hypothyroidism high doses can be used to tx thyroid storm most toxic and potent of HIV drugs a front brain problem used for Miliary TB (gets great CSF concentrations) should be avoided with administration of levodopa all antipsychotics have risk of this >10 mcg/kg/min of dopamine BBW for increased risk of venous thromboembolism Tacrine Donepezil Rivastigmine Galantamine severe in patients presentings w/ hyperthermia Systemic autoimmune dz affects joints symmetrically stiffness worse in morning the most common virus for Hep B, Hep C and RSV (Respiratory Synctal Virus/ pulmonary infection) Teratogenic anemia Vit D deficiency -- softening of the bones/osetomalacia potent enzyme inducer causes red fluid discolorations anchor drug of Complera 2nd gen NNRTI hydrophilic analogue of another drug used to tx Influenza A Biphosphonate you can take postbreakfast extends lock out period of ED drugs used only as "booster" most potent CP450 inhibitor CP450 Inhibitor Interacts w/ inhaled c.steroids

271.

272. 273.

250.

Pinworm

274.

251.

PIs for Hep C Pituitary gland Plasminogen Activators (TPA) Positive Iontrope (beta-1 agonist) potassium Potent cholinergic phenomenon PPI

275.

252. 253.

276.

277.

254.

278.

255. 256.

257.

279.

280.

258.

Pramipexole or Rospinirole Pravastatin Preferred Intraarticular Corticosteroids Probenecid Procainamide Prodrug Progestin only OC Progestins

281. 282.

259.

260.

283. 284.

Ribavirin AE Rickets Rifampin Rilpivirine Rimantidine Risedronate Ritonavir Ritonavir Ritonavir

261. 262.

285.

263.

286.

264.

287.

265.

288.

266. 267. 268. 269.

prolactin Propofol Propofol C/I Propranolol MAO for migraines

289.

290.

291.

292.

Rumack-Matthew Nomogram Scurvy Seeding

used to assess blood levels in APAP overdose deficiency in Vitamin C When virus DNA integrates w/ hosts DNA. Point of no return protects central DA stores in CNS MAO-type b common side effect of TCAs and SSRI's pentobarbital secobarbital PED-5 inhibitor priapism Blue-tinted vision Flatulence aldosterone loves least greasy topical tx (dries fastest) gynecomastia Fluoxetine most effective at decreasing LDL IV steroid can't combo w/ AZT (Zidovudine) Potassium Chloride decreased efficacy in ptts >130% IBW fertility returns to normal after 30 days GI agent containing Aluminum (may chelate) used for ulcerative colitis and RA Dilate pupils (mydriasis) Fast HR Dilates bronchi Glycogen-->glucose Adrenaline Pseudoephedrine

318. 319.

TCA example TCA OD treatment TCA overdose TCAs Tenofovir Terbinafine Teriparatide Tetracycline Tetracyclines Thiazide

Imipramine Bicarb Hallmark sign:: prolonged QRS interval on EKG number 1 cause of intentional suicide in US NtRTI used mostly in PREP DOC for onychomycoses BBW for osteosarcoma DOC for lyme disease C/I in pregnant women and children-causes yellow/deformed teeth Diuretic w/ risk of: hypokalemia, hypercalcemia, hypo magnesium, hyper urea, and hyperglycemia Diuretics working in distal tubule elderly w/ chronic ASA OD presentation used for infantile spasms and weight loss increase skin turn-over to decrease lesions Capsaicin Methylsalicylate not effective in women >198pds available 21/14/7mg/day MAO-Is used to activate treats insomnia AE- orthostatic hypotension and priapism Bradykinesia Rigidity Tremor vasoconstrict and block pain pathway Do not use w/in 24hr of ergot

293. 294.

320.

321.

295.

Selegiline Sexual dysfunction Short acting barbituate Sildenafil Sildenafil AE Simethicone sodium Solutions/lotions Sprionolactone AE SSRI example Statins Status Asthmaticus tx Stavudine (D4T) Stops heart for lethal injections subdermal Progestin implants

322.

296.

323. 324. 325. 326.

297.

298. 299.

300. 301. 302.

327.

328.

Thiazide and Indapamide Tinnitus Tompiramate Topical Retinoids Topical therapies for arthritis Transdermal contraceptive Transdermal Patch Tranylcypromine Trazadone

303. 304. 305. 306. 307. 308.

329. 330.

331.

332.

309.

333.

334.

310.

Sucralfate Sulfasalazine Sympathetic actions

335. 336.

311. 312.

337.

Triad of Parkinson's Dz Triptans Triptans (serotonin receptor agonist) Typical ARV recipe Ultra-short acting Barbituate

338. 313. 314.

Sympathomimetic Syrup of Ipecac Tadalafil Tapeworm TB tx regimen

339.

follow w/ water to prevent dry heaving ED drug you can take just prior to sex tx= praziquantel or albendazole 4 drugs x 4 mths then 2 drugs x 2 mths
340.

315.

2RTI and 1: NNRTI, PI, or II Methohexital Thiopental

316. 317.

341.

342.

Unfractionated Heparin

doesn't cross placenta- okay in pregnancy Monitor PTT dose 80/18 units/kg/hr prodrug of acyclovir widest spectrum of use (for seizures) prophylaxis for migraines AE: hepatotoxicity Gold standard for Gram (+) Red man syndrome DOC for prophylaxis migraine if patient also has HTN or angina chronic tox causes painful/tender long bones and alopecia antioxidant helps maintain B12 cells may help form renal stones DOC for prophylaxis migraine if patient also has seizures, anxiety or bipolar oldest NRTI AE: Anemia 1st line IV for osteoporosis

343. 344.

Valacyclovir Valproic Acid

345.

Vancomycin Verapamil Vitamin A Vitamin C (Ascorbic Acid)

346. 347. 348.

349. 350.

VPA, Topiramate, Gabapentin Zidovudine (AZT) Zoledronic acid

351.