We cover a JAMA Clinical Reviews podcast on lyme disease, including some myth-busters. *Doxycycline can be used, safely, in kids < 8 years old *Testing for lyme is a mess because : (1) we test patients with ultra low probability of disease (2) we test patients who shouldn't be tested (i.e. have erythema migrans) (3) the tests are a pain to interpret *Lyme disease is spreading further south and west in the US, into Canada, and it's also increasingly found in Europe. We then delve into core content for Rosen's, Tintinalli, and the IDSA 2006 guidelines. Thanks for listening! Jeremy Faust and Lauren Westafer FOAMcast.org