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Breast
Development of breast
Before birth
Develop from a invagination of ectoderm during 4th week of development along mammary ridge (Milk line) Milk line runs from axilla to mid inguinal region Breast is a modified sweat gland
Development of breast
Development of breast
After birth
Lobule formation occurs in female breast after puberty Development of female breast is divided into five phases
age of the female parity of female stage of pregnancy & lactation Stage of the menstrual cycle
Very few glands & fat No alveoli
Before puberty
Puberty
Increase in size due to the increase in fatty tissue Areola & nipple are formed Breast lobules are formed Fibrous tissue separates breast lobules
Alveoli bud off from smaller ducts within a lobule Breast enlarge in size (400g) Secretary fat globules are present inside alveoli When lactation ceases atrophy of lobules and glands, replaced with fatty tissue
Increase in size in mid cycle due to increase in blood flow Involution of glandular tissue replaced by fatty tissue Decrease in size Decrease in elasticity of connective tissue
After menopause
Extends from sternal edge to mid axillary line Extends from 2nd to 6th ribs Over lies pectoralis major, seratus anterior, rectus sheath & external oblique muscle
Axillary tail
Smaller projection of upper outer quadrant of the breast Usually lies in subcutaneous fat of the axilla Rarely it penetrates the deep fascia of axillary floor & lie with the axillary lymph nodes (frequently mistaken for axillary lump) Pigmented projection of skin 15 20 lactiferous ducts drain each lobe of breast drains to the surface Smooth muscles of the nipple cause erection to sexual stimuli Terminal part of the lactiferous ducts are dilated to form sinuses
Nipple
Nipple
Areola
Pigmented skin surrounding the nipple Large sebaceous glands & areolar glands form small projection on the skin (Tubercles of Montgomery)
Section of breast
Lactating Breast
Capsule of Breast
Formed by condensation of superficial fascia of chest wall, posterior to the breast tissue (Upward continuation of membranous layer of superficial abdominal fascia) In young females suspensory ligaments help to keep the protuberance of the breast There is a space between capsule of breast & fascia over the pectoralis major muscle (Retro mammary space)
Main supply of the breast Branch of 2nd part of axillary artery Supply medial part of the breast Branch of a 1st part of subclavian artery Branches of descending thoracic aorta
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Venous drainage
Circumareolar venous plexus & veins from glandular tissue draining into the deep veins Skin & superficial fascia drain to superficial veins Veins usually run along with arteries Drain to internal thoracic, axillary & posterior intercostal veins
Medial part to parasternal lymph nodes Some lymphatic in upper part of breast drain to supraclavicular lymph nodes Few lymphatics run along the intercostal vessels to intercostal lymph nodes
Anterior group
Along lower border of pectoralis major
Posterior group
Lateral group
Central group
Inside the axillary fat
Apical group
Posterior to clavicle & along axillary vein Subclavian lymph trunk begins
Supratrochlear nodes
Proximal to medial epicondyle
to apical nodes
Right side
Drains into subclavian vein or joins the right jugular trunk Usually drains to thoracic duct
Left side
Secretion of milk
Supernumery nipples Small or absent breast (Amazia) Retracted nipples Breast abscess Cellulites of skin
Infection of breast
Tumors
Benign (harmless)
Fibroadenoma
Fibroadenosis
Malignant (cancer)
Treatment for breast cancer
Detection of breast cancer
Mammogram
Mammogram
Mammogram
Summary
Development Structure Lymphatic Drainage Clinical Importance