Catching up with other hospital consortia in the world

Tayfun Basal Sales Manager Turkey t.basal@elsevier.com Mob phone: 0 533 771 8689

Charles Pallandt Regional Director Turkey, Middle East and Africa

Agenda
Introduction: Health Science market analysis.
Current and future content on ScienceDirect:

- Journals including Cell Press - Books Xpharm PharmaPendium

Health Science Market Share 2006 by Publishers

Elsevier Market share (% papers published) in Health Science

30

25

20

Percentage

15

10

Harcourt acquisition

97

98

99

00

01

02

03

04

19

19

19

20

20

20

20

20

Elsevier (3/4%) outperforms average market growth 2/3%)

5

20

05

Health Science Summary by Publisher

Influence (or Citation Share) - Indicates the share of citations that the publisher has. Citations have been measured over a five-year period (2001 2005). 6

Thousands

60

The impact of electronic acces: Turkey; accelerated output after universities were on Science Direct
Article output 1996-2005

50

40

30

20

Turkey Iran Greece Italy Spain France Chech Republic Poland

Turkish CAGR (00-05) : 25%

10

0 1996 1997 1998 1999 2000 2001 2002

7

2003

2004

2005

Source: Thomson Scientific (ISI)

Content on ScienceDirect today

Handbooks Reference Works Book Series ~3 million articles 1995 - present 7 series 51 titles 145 titles

~4 million articles

Backfiles pre 1995

2000 journals

Journals on ScienceDirect

Contains >2000 journals Elsevier Science Pergamon North Holland Academic Press Harcourt Health Sciences Cell Press etc > 7.9 million full-text articles 23 subjects Articles In Press Backfile articles back to Volume 1, Issue 1

All journals are available on ScienceDirect from volume 1, issue 1

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The Lancet vol 1, no. 1 - 1823.

ScienceDirect Content Cell Press

Cell Press publishes prestigious highlycited biomedical research journals

Cell Neuron Immunity Molecular Cell Developmental Cell Cancer Cell Current Biology Structure Chemistry & Biology Cell Metabolism
12

Cell
The 2004 Nobel Prize in

Physiology/Medicine awarded to Richard Axel, M.D., and Linda S. Buck, Ph.D., for their work studying the organization of the olfactory system was based on research published in their seminal 1991 Cell paper.

13

ScienceDirect Content Cell Press

Ground-breaking articles from the Cell Press journals are now available at the desktop.

Discovery 1984 Ubiquitin as central cellular regulator 2003 Gene required for stem cell pluripotency Knowledge 1979 Tyrosine phosphorylation 1989 Rag1 mediates antibody diversity Impact 1974 First cloning of eukaryotic gene 1994 Mechanisms of long-term memory

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Cell Press: High-impact journals available at the desktop

Each Cell Press title is at or near the top of its ISI subject category.
Cell with a current Impact Factor of 27.254 according to the 2002 ISI Journal Citation Report has been the top research journal in the cell biology and biochemistry and molecular biology categories six of the last seven years.

Similar impressive statistics apply to Neuron and Immunity in their respective categories. Newer titles like Molecular Cell, Developmental Cell and Cancer Cell have quickly established themselves as top-tier journals within their respective communities.
15

ScienceDirect Content Online Books

Book Series Reference Works/ Encyclopedia

Handbooks (NEW)

7 packages 163 titles

51 Titles

16

7 series 164 volumes

Elsevier Book Series

Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Now with over 400 volumes since 1955, the series contains much material still relevant today truly an essential publication for researchers in all fields of life sciences.

"The 'Methods in Enzymology' series represents the gold-standard." Neuroscience "Incomparably useful." Analytical Biochemistry "A series that has established itself as a definitive reference for biochemists." Journal of Chromatography

19

Biomedical Method Research Title

20

Elsevier Reference Works

High quality reference material. Highly detailed and structured. Highly used and cited. 51 now available on ScienceDirect including:

Encyclopedia of Cancer Encyclopedia of Endocrine Diseases Encyclopedia of Gastroenterology Encyclopedia of Hormones Encyclopedia of Human Nutrition Encyclopedia of Immunology Encyclopedia of the Neurological Sciences Encyclopedia of Toxicology Encyclopedia of Virology Encyclopedia of Biological Chemistry Meyler's Side effects on Drugs Encyclopedia of Genetics 21

Elsevier Handbooks series

Launched 7 series in Chemistry, Mathematics,

Physics and Economics in 2005. Chapters by commissioning & invitation only. Validated, refereed and edited by authoritative editors Highly cited. Usually long life cycle up to 15 years.
Forthcoming in 2006 Handbooks of Neurology

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Forthcoming in August 2007

Over 4000 eBooks!

23

www.sciencedirect.com

26

Find journals/books of interest.

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Find journals/books of interest. Option 2

28

Find journals/books of interest

29

Find journals/books of interest

30

Find articles of interest

31

Find journal of interest

32

Find articles of interest

33

Find articles of interest

34

Searching Quick search

35

Searching for more advanced features

36

Searching

37

Searching

38

Example

39

Example

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Usage statistics

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Overall ScienceDirect Usage

Usage of full text articles
300,000,000 250,000,000 200,000,000

270 M

150,000,000 100,000,000 50,000,000 0

53 M 85 M

86 M 140 M

10 million regular users

36 full-text downloaded every second of a regular working day.

2002

2003

2004
42

2005

Health Science Market Share 2006 by Publishers

Science Direct usage is more than fair share!

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Usage statistics

Available via http://usagereports.elsevier.com (Password protected)

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xPharm
A Pharmacological Reference Database for Life Scientists

Presented by: Title: Date:

What is xPharm?
An easily accessed, well thought through and highly functional repository of pharmacological information that quickly provides answers to in-depth pharmacology questions. Agents Targets Disorders Principles And the mechanisms that govern their interaction
xPharm is an exceptional resource a one of a kind undertaking that is an encyclopedia of modern pharmacology
Howard Gendelman, M.D. Chair, Department of Pharmacology University of Nebraska

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Easy to use

Consistent color coding to orient the user Easy Browsing from table of Contents Support for basic and advanced queries

alzheimer

49

Detailed
xPharm displays more detailed information about pharmacologically relevant targets than any print and online source
Classification and alternate names Pharmacological regulation Disease associations

Assays

50

Extensive & Comprehensive

xPharm automatically links researchers to related sources of information

Genetic database Protein database Literature Full-text articles Additional supporting material, such as an ECG Library

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The Essential Drug Safety Resource

PharmaPendium

A single source web based system that allows a single search to retrieve Preclinical animal, Human clinical trial and Post-market safety data, and intelligent pathways to that data.

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Who would find this useful?

Preclinical Safety Teams Toxicologists Discovery Toxicologists Safety Pharmacologists DMPK, ADME Medicinal Chemists Clinical Researchers Regulatory Affairs

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PharmaPendium: Sources

3,000 Drugs covered FDA Approval Packages

Preclinical, clinical Major reference work Drug Monographs: Current & Withdrawn after 1997

Meylers Side Effects of Drugs 15th Edition

Package Insert information (Labels)

Toxicity/Metabolites extracted from literature. Adverse Event Reporting System (AERS)

Post market

Drug/Target associations
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FDA Approval Package Database

US-approved drugs (1992 and later)

1400+ drugs with approval documents 700 with full Review sets (most 1992 and later); over 700 others with partial packages. ~ 23,000 Documents ~ 650,000 pages of information ~ 300,000 extracted safety records

Preclinical & Clinical data extracted.

Full FDA reviews, label updates, warnings, etc. Able to be navigated via text search, chemistry search, and browsed by target, drug, class.

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FDA Database: July Update

Update:

9,800 new searchable documents 204,000 new searchable pages. 33,000 documents 850,000 pages

After 1st Update:

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FDA Database: July Update

Free evaluations to all presented products for the coming 6 weeks: 1. Journals / e-books on Science Direct 2. Cell Press 3. Xpharm 4. PharmaPendium

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Thank you for your attention and enjoy trialling!

Elsevier, Amsterdam, The Netherlands

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