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Objectives
The learner will be able to identify the structures of the heart.
Right-side Anatomy
Vena cava Right atrium Tricuspid valve Right ventricle Pulmonic valve
Middle Anatomy
Pulmonary artery Pulmonary capillary Pulmonary vein
Left-side Anatomy
Left atrium Mitral valve Left ventricle Aortic valve
Objectives
The learner will be able to state the definition of basic hemodynamic terms : Stroke volume, stroke volume index Ejection fraction Cardiac output, cardiac index Preload Afterload Contractility
Ejection Fraction
EF = end diastolic volume end systolic volume end diastolic volume Normal range = 60-75% of end diastolic volume
CO/ CI
Causes : MI Shock HR SV (-) inotropes vascular resistance Cardiac tamponade Hypovolemia Valvular heart disease High PEEP
CO / CI
Causes : Hypertension vascular resistance Pulmonary edema metabolic state Positive inotropes
Myocardial Oxygen
Heart Rate
HR MVO2 demand
Preload
Definition Volume in ventricle at end diastole.
OR Pressure exerted on walls of ventricle at end diastole.
Preload
Clinical Significance Represents fluid returning to heart Also known as filling pressure preload, MVO2 demand
Preload
Measurement Preload is assessed by measuring the filling pressure of each ventricle.
Right ventricle preload CVP Left ventricle preload PAOP
Afterload
Definition Amount of pressure the ventricle must work against during systole to open the valve.
Afterload
Clinical significance afterload work of the heart MVO2 demand
Afterload
Factors that increase afterload: Vasoconstriction Valvular stenosis blood volume
Afterload
Factors that decrease afterload Vasodilation
Afterload
Measurement Afterload is assessed by measuring the resistance in the ventricle during systolic ejection.
Right ventricle afterload PVR Left ventricle afterload SVR
Contractility
Definition The hearts contractile force or muscle strength
Contractility
Factors that influence contractility: Starlings Law Sympathetic nervous system Pharmacologic agents
Starlings Law
The force of ventricular ejection is related to : The volume in the ventricle at enddiastolic (preload). The amount of myocardial stretch placed on the ventricle.
SNS fibers are found throughout the atria and ventricles The most important regulatory factor for myocardial contractility
Pharmacologic agents
Inotrope ino = strength tropy = enhancing Positive inotrope = stronger contraction Negative inotrope = weaker contraction
Positive Inotropes
digoxin epinephrine dopamine (Intropin) dobutamine (Dobutrex) inamrinone (Inocor) milrinone (Primacor)
Negative Inotropes
Hemodynamic Profiles