Huntingtons Disease

Nyimas Ratih Amandhita Nakita Putri 030.09.176

degeneration of brain cells in certain areas of the brain

Not only is there neuronal loss but there is also a decrease in the level of a number of neurotransmitters and associated enzymes, together with abnormalities in some receptor sites

It is a hereditary disease. Passed from parent to child through a mutation in normal gene

The prevalence is similar for men and women

Western European

Early signs of the disease vary greatly from person to person

mood swings
trouble driving, learning new things, remembering a fact, answering a question, or making a decision

Sudden jerky

Severe problems with balance and coordination

rapid eye movements

Swallowing problems

Hesitant, halting or slurred speech Dementia

Anamnesis & physical examination

neurological exam

CT-Scan

Depression

Suicide

Infection

Antipsychotic drugs

fluoxetine, sertraline, nortriptyline

Tranquilizers

lithium

References
http://www.mayoclinic.com/health/huntingto ns-disease/DS00401 http://www.nlm.nih.gov/medlineplus/hunting tonsdisease.html http://www.ninds.nih.gov/disorders/huntingt on/huntington.htm http://www.medicinenet.com/huntington_dis ease/page3.htm