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Animal Cell
Cell Boundaries
Plasma Membrane:
An outer covering that defines the cell boundary Controls the movement of material such as gases, nutrients and waste products into and outside the cell
Cell Coat:
Consists of glycogen and polysaccharides Provides biochemical identity at the surface of cells (molecular recognition) Various antigens are part of the cell coat as for example the MN and AB antigens on red blood cells Receptor molecules are integral components of the cell surface (recognition sites)
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Nucleus
Contains the genetic material. Consists of : - Nuclear membrane with nuclear pores - Nucleolus: site for synthesis of ribosomal RNA (rRNA). The areas of DNA encoding rRNA are collectively known as the Nucleoler Organizer Region (NOR) Note that prokaryotes (like bacteria) do not have a nucleus. In bacteria, the genetic material is present as a long, circular DNA molecule that is compacted in an area called the nucleoid region.
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Endoplasmic Reticulum (ER): 1. Smooth ER: serve as the site for the synthesis of fatty acids and phospholipids 2. Rough ER: studded with ribosomes which serve as sites for the translation of mRNA into proteins. Mitochondria: - Are the sites of oxidative phases of cell respiration chemical reactions generate large amounts of ATP - Contain a type of DNA distinct from that in the nucleus - Can duplicate themselves and transcribe and translate their own genetic information
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Centrosome: Also called the "microtubule organizing center", is an area in the cell where microtubules are produced. Within an animal cell centrosome there is a pair of small organelles, the centrioles, each made up of a ring of nine groups of microtubules. Centerioles are associated with organization of spindle fibers in mitosis and meiosis.
The chromosomes serve as the vehicle for the transmission of genetic information Chromosomes are most easily visualized during cell division and take distinctive lengths and shapes. Each chromosome contains a condensed or constricted region called centromere to which the spindle fibers attach during cell division. Two arms extend from each side of the centromere: - p arm (short arm) above the centromere - q arm (long arm) below the centromere
The chromatin material just before cell division forms into chromosomes. Each chromosome is made up of two longitudinal strands called sister chromatids. 10
Classification of chromosomes
1) Sex and Autosomal chromosomes: Sex chromosomes: X and Y (humans and animals) or W and Z (in birds) males: XY and ZZ , females: XX and ZW Autosomal chromosomes (autosomes): chromosomes other than the sex chromosomes
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2) Chromosomes are classified based on the position of the centromere into: Metacentric: centromere location is in the middle of the chromosome and the chromosome is V-shaped during anaphase Submetacentric: centromere location is between the middle and the end of the chromosome and the chromosome gets an L shape during anaphase . Acrocentric: centromere location is close to the end of the chromosome and the chromosome is J-shaped during anaphase Telocentric: centromere location is at the end of the chromosome and the chromosome is I-shaped during anaphase
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3) Human chromosomes are classified based on size and shape into 8 groups:
Large, metacentric
Large, submetcentric
small
Karyotype: is the characteristic chromosome complement of a eukaryote species. Often used to refer to the arrangement of metaphase chromosomes in a sequence according to length and position of the centromere. Karyogram: The pictorial representation of the entire set of chromosomes.
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Polyploidy in animals
Examples in animals are more common in the 'lower' forms such as flatworms, leeches, and brine shrimp. Polyploid animals are often sterile, so they often reproduce by parthenogenesis. Polyploid lizards are also quite common and parthenogenetic. Parthenogenesis is an asexual form of reproduction found in females where growth and development of embryos or seeds occurs without fertilization by a male. The offspring produced by parthenogenesis are always female in species that use the XY sexdetermination system but they will be male if two like chromosomes determine the male sex (such as the ZW sex-determination system).
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Domestic cat
Laboratory mouse Rabbit Hare Gorillas, Chimpanzees Elephants Donkey Dog
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40 44 46 48 56 62 78
Domestic pig
Laboratory rat Human Domestic sheep Cow Horse Goats
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42 46 54 60 64 60
Chicken
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Silkworm
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Down's syndrome: caused by an extra copy of chromosome 21 (trisomy 21). Is the most common trisomy. Edwards syndrome, which is the second-most-common trisomy. It is a trisomy of chromosome 18. Klinefelter's syndrome (XXY). Men with Klinefelter syndrome are usually sterile, and tend to have longer arms and legs and to be taller than their peers. Boys with the syndrome are often shy and quiet, and have a higher incidence of speech delay Turner syndrome (X instead of XX or XY). In Turner syndrome, female sexual characteristics are present but underdeveloped. People with Turner syndrome often have a short stature XYY syndrome. XYY boys are usually taller than their siblings. Like XXY boys and XXX girls, they are somewhat more likely to have learning difficulties. Triple-X syndrome (XXX). XXX girls tend to be tall and thin.
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