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Dr. Ahmad Kharis Nugroho, Apt. Dr.rer.nat. Ronny Martien C.M. Ratna Rini N., M.Pharm., Apt.
Spatial placement site specific targeting delivery Temporal delivery rate / time efficiency
Points to concern
Challenges (read: barriers) of delivery Ideal system Technology development Critical factors
- Continuous release
release
Competence Indicators
Students can explain the role of drug delivery system in encouraging patientoriented therapy Students are capable to distinguish the advanced drug delivery systems based on the mechanism of delivery and release Students are able to identify the critical factors of the delivery systems learnt
Conscience to develop
The objectiveness in accessing information Critical and logical thinking The importance of communication and team work/collaboration spirit Self confidence to decide the right things Imagination leading to creativity
Compassion held
Willingly to contribute to the transfer of correct information about drug delivery system Highly motivated to design the drug delivery system which fully concerns on patients overall condition
Menu
Week I-II Agenda Nanotechnology delivery PIC Dr. Ronny Martien Dr. Ronny Martien Dr. Akhmad Kharis, Apt.
III-IV
V-VII
Menu
Week Agenda Mid exam VIII-X Pulmonary and nasal delivery Iin, M.Pharm, Apt PIC to guide
XIXIII
Iin, M.Pharm,Apt
Final exam
Schedule description
Dr. Akhmad Kharis, Apt. and Dr. Ronny Martien will teach on weekdays schedule for all classes Saturday classes are only carried out if Dr. Akhmad Kharis, Apt. is not available to give lectures on weekdays due to must-to-do agendas on Gadjah Mada University (there will be notification) Learning with Iin, M.Pharm will start after mid exam for 6 weeks
Distribution of assessment
I:K:R =50% : 25% : 25% Description of I mark:
Final
exam : max 30 Assignment & presentation : max 20 (10 for presentation, 10 for discussion)
Pulmonary
drug delivery (3) Nasal delivery (1) Sustained delivery & Pulsatile delivery (2) Oral macromolecular delivery (3)
Iin, M.Pharm:
Pulmonary
Anatomy
and physiology of lung, lung natural defense and physical factors affecting drug disposition Design of pulmonary delivery system Exuberra review
Nasal
Anatomy
of nose and reason behind delivery Design of nasal delivery system Review on pulmonary and nasal delivery
Sustained
meeting
Oral macromolecular delivery (3) 2 meetings (+review and reflection) Strategy to overcome enzymatic barriers Role of penetration enhancers Strategy to overcome efflux pump
Aspects to discuss
Concept of delivery
Description
of either the anatomy and physiology of the site of action or the physiological barriers The purpose of the delivery system
The unique mechanism of the system What critical factors to concern and why?
Handout
Use slides of Power Point (use 3 slides/page no more than 8 pages) No plagiarism!!! If you refer to any articles or figures, always refer on a right manner (with acknowledgement) and the statement of only for learning purposes Handout should be copied and distributed at least one day before class If the handout needs to be revised, revision will be done after class
Recommended references