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H2CO3 H+ 6
+
5 HCO3-
4
PERITUBULAR
TUBULAR FLUID RENAL TUBULAR CELLS CAPILLARY
Ammonia Buffer
Depends on the generation of ammonia (NH3) from
amino acids in renal tubular cells.
NH3 diffuses into the tubular lumen, where it may
combine with secreted H+ to form ammonium
(NH4+)
NH4+ is excreted in the urine in combination with Cl-
from NaCl
GLOMERULUS
Cl-
1
H+
3 +
NH3
2
Cl-+NH4 NH3 Glutamine
4
NH4Cl
HPO42- + H+ 1
3
H2PO4- + Na+
4
NaH2PO4