Académique Documents
Professionnel Documents
Culture Documents
Bipolar I Disorder
Episodes of mania or mixed episodes that include
symptoms of both mania and depression. Three of the following (four if mood is irritability)
Increase in activity level - at work, socially, or sexually Unusual talkativeness, rapid speech Flight of ideas or subjective impression that thoughts are racing Less than the usual amount of sleep needed Inflated self-esteem, belief that one has special powers, talents, abilities Distractibility; attention easily diverted Excessive involvement in risky activities
Unipolar-Bipolar Distinction
Variable Motor Activity Sleep Age of onset Unipolar Typically agitated Difficulty sleeping Late 30s to early 40s Bipolar Typically retarded when depressed Sleeps more than usual when depressed Thirty First-degree relatives at high risk for unipolar and bipolar About equal in gender Best response to lithium
Family History First-degree relatives at high risk for unipolar depression Gender Much more common among women Biological Some response to Treatment lithium but better to tricyclics
Cyclothymic Disorder
For at least 2 years (1 year for children), the
presence of numerous periods with hypomanic symptoms and numerous periods with depressive symptoms that do not meet criteria for a Major Depressive Disorder During the above 2-year period, the person has not been without symptoms for more than 2 months at a time No Major Depressive Disorder, Manic Episode, or Mixed Episode has been present during the first 2 years of the disturbance
Dysthymic Disorder
Depressed mood for most of the day, for more days than
not, for at least 2 years (1 year in children) Presence, while depressed, of two or more of the following:
poor appetite or overeating insomnia or hypersomnia low energy or fatigue low self-esteem poor concentration or difficulty making decisions feelings of hopelessness
biased toward negative interpretations People acquire negative schema due to experiences in childhood (loss of a parent, rejection by peers) Negative schema are activated whenever they encounter new situations which resemble (even vaguely), the conditions in which the schemata were learned The negative schemata fuel and are fueled by cognitive biases, which lead depressed people to misperceive reality
World
I cannot cope
Future
Things will always turn out poorly
failure. Following a disagreement with the boss She thinks everything I say is stupid. During an argument with her husband He thinks I never get anything right. After a complement from a friend He just said that because he feels sorry for me.
which Beck outlines Negative thinking decreases after treatment Although pessimistic, depressed people sometimes are actually more accurate than normal (e.g., judging probability of success) Whether depression is the result of cognitive biases or vice versa is not clear
Learned Helplessness
Sense of Helplessness
Depression
Attributional Theory
Aversive events
Depression
Hopelessness Theory
Sense of hopelessness; no response available to alter the situation and expectation that desirable outcomes will not occur
Aversive events
Depression
Interpersonal Theory
Depressed people may elicit negative reactions
from others The interactions of depressed people and their spouses are characterized by hostility on both sides Depressed people are often low in social skills and their own behavior contributes to the high levels of stress they experience The constant seeking of reassurance is a critical interpersonal variable in depression
relatives of bipolar patients also have experienced an episode of mood disorder For bipolar disorder, the concordance rate for identical twins is 72% and in fraternal twins about 14% The information indicated that for unipolar depression, genetic factors, although influential, are not as decisive as with bipolar disorder
leads to depression and a high level to mania. Depression due to low levels of Serotonin. Tricyclic drugs - prevent the reuptake of both norepinephrine and serotonin by the presynaptic neuron after it has fired. Monoamine oxidase inhibitors - keep the enzyme monoamine oxidase from deactivating neurotransmitters, thus increasing the levels of norepinephrine and serotonin Selective serotonin reuptake inhibitors - specifically inhibit the reuptake of serotonin
norepinephrine and serotonin when they are first taken, but after several days the neurotransmitters return to their earlier levels. The drugs take 7-14 days to work Drugs which involve other mechanisms also relieve depression Future research will center on serotonin receptors
also has effects on the hypothalamus (hormonal secretion) Hormones secreted by the hypothalamus also affect the pituitary gland and the hormones it produces Because of its relevance to the vegetative symptoms of depression (e.g., disturbances in appetite and sleep), the hypothalamic-pituitary-adrenocortical axis is thought to be overactive in depression. Levels of cortisol (an adrenocortical hormone) are high in depressed patients. High levels of cortisol may lower the density of serotonin receptors and impair the function of noradrenergic receptors.
Childhood Depression
As with adults, depression in childhood is
recurrent and has high rates of comorbidity (e.g., anxiety disorders, conduct disorder) Theories of etiology point to genetic factors and interpersonal relationships. Research on the treatment of childhood depression does not support the use of antidepressants. Both CBT and Interpersonal therapies have been used and combined with family and school interventions
Suicide
Characteristic Gender Age Method Attempters Majority Female Predominantly Young Low lethality (e.g., pills) Completers Majority Male Risk increases with age More violent (e.g., guns) Depression with hopelessness Death
Dominant Affect Depression with anger Motivation Attitude Toward Attempt Change in situation Cry for help Relief to have survived Promises not to repeat
consciousness The common stimulus in suicide is intolerable psychological pain The common stressor in suicide is frustrated psychological needs The common emotion in suicide is hopelessnesshelplessness The common cognitive state in suicide is ambivalence The common perceptual state in suicide is constriction
communication of intention The common consistency in suicide is with lifelong coping patterns