Académique Documents
Professionnel Documents
Culture Documents
Introduction Primary prevention: Prevention of Occurrence of disease Secondary prevention: Early detection of disease
Early detection
The term early detection of disease means detecting a disease in earlier stage that would usually occur in standard clinical practice. This denotes detecting disease at a presymptomatic stage, at which point the patient has no clinical complaint and , therefore, no reason to seek medical care for the condition.
DISEASE PRESENT
Clinical Outcome No Disease Biologic Onset of Disease Symptoms First Appear Disease Diagnosed
Therapy Given
DISEASE PRESENT
Normal
Preclinical Phase
Therapy Given
Primary prevention
Secondary Prevention
Tertiary Prevention
Normal
Preclinical Phase
Therapy Given
Normal
Preclinical Phase
Therapy Given
Important assumptions
Preclinical phase Detectable preclinical phase Lead time Critical point All or most clinical cases of a disease first go through a detectable preclinical phase. In the absence of intervention, all or most cases in a preclinical phase progress to clinical phase
DISEASE PRESENT
Normal
Preclinical Phase
Therapy Given
DISEASE PRESENT
Therapy Given
Lead Time
Clinical Outcome No Disease Biologic Onset of Disease
Symptoms
Therapy Given
Critical Point
Biologic Onset
Final Outcome
NORMAL CERVIX
CARCINOMA IN SITU
NORMAL CERVIX
CARCINOMA IN SITU