PERIOD 1 st -31 st july 2011 PRESENTERS -Dr. BOSIRE / Dr. KURUGA FACILITATOR -Dr. Kagema DATE 12 th August VENUE DEPT OBS/GYN ( UON)
INTRODUCTION
- 600,000 Women die globally from pregnancy related conditions
- Most deaths are preventable
- Deaths in developing countries - >2/3rds
DEFINITIONS Maternal mortality :- Death of a woman while pregnant or within 42 days of termination of pregnancy irrespective of the duration or site of pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes (WHO, Geneva 1992). Death resulting from complications of induced abortion is considered a maternal death.
Causes of maternal death Direct - 75- 80 % 0f maternal deaths -results from interventions, omissions, incorrect treatment -or chain of events resulting from pregnancy or delivery related conditions Indirect - 20-25% of maternal deaths - From pre- existing disease- DM, cardiac disease, malaria, TB , HIV etc or, is unrelated to pregnancy related condition, but is aggravated by physiologic effects of pregnancy
Maternal mortality ratio Number of maternal deaths per 100,000 live births in a given period. Its a measure of obstetric risk i.e. risk of death once a woman has become pregnant.
Maternal Mortality rate The number of maternal deaths in a given period of time per 100,000 women of reproductive age (15-49) during the same period. This measure reflects proportion of women who get pregnant in a year and risk of death among them. It reflects the frequency with which women are exposed to risk of death through their fertility ANC attendance among deliveries
Outcomes of deliveries Outcome Number Live Birth 850 FSB 7 MSB 14 BBA 16 Maternal mortality
Ward Number L/W 4 GF-A 2 GF-B 0 1A 1 1C 0 1D 0 ICU 4 Renal Unit 3 TOTAL 14 KNH Maternal mortality ratio- JUNE 2011
14/887 x 100,000= 1578 per 100,000 live births
May 2011= 882 per 100,000 live births June 2011 =1078 per 100,000 live births March 2011 = 1708 per 100,000 live births KNH audit 2010=1222 per 100,000 live births KDHS 2008 =488 per 100,000 live births KDHS 2003 =414 per 100,000 live births WHO 2005 =560 per 100,000 live births
Causes of maternal mortality
Cause of death No. % Eclampsia (CVA, ARF) Post MVR Cardiac dse 4 1 35.7% 7.14% Sepsis 5 35.7% PPH 1 7.14% Uncontrolled chronic DM&HTN (ARF) 1 7.14% Meningitis/Encephalitis 1 7.14% Anaesthetic Complication 1 7.14% Diagnosis Number Percentage Threatened Abortion 42 6.55 Ectopic pregnancy 34 5.3 Peuperal complications 29 4.52 Terminated abortions 119 18.56 Pelvic masses 15 2.34 AUB 74 11.54 Ca cx 37 5.77 GTN 8 1.25 PV DISCHARGE 18 2.81 INFECTION 78 12.17 OTHERS 153 23.87 DVT 7 1.10 DIAGNOSIS NUMBER PERCENT IUFD 5 0.78 CA OVARY 5 0.78 CA ENDOMETRIUM 4 0.62 INFERTILITY 6 0.94 TOTAL 641 100 STRANGE CASES DIAGNOSIS NUMBER MENSES 1 FORNIX LACERATION 1 APPENDICITIS 1 PHYSIOLOGIC PREGNANCY CHANGES 2 HEPATIC ENCEPHALOPATHY 2 Admission to other units UNIT DIAGNOSIS NUMBER ICU INTRACRANIAL BLEED PET CA OX DEBULKING POST MVR PEUPERAL SEPSIS 1 1 1 1 RENAL UNIT PREECLAMPSIA VVF CACX POSTABORTAL SEPSIS 4 1 2 2 ACUTE ROOM A&E PEUPERAL SEPSIS IUFD + COMA HEPATIC ENCEPHALOPATHY 1 1 1 TOTAL 15 Neonatal morbidity and mortality Live Birth: Newborn that breathes spontaneously or shows signs of life such as a heartbeat of definite spontaneous movement of voluntary muscles Perinatal period: Period after birth of an infant weighing more than 500g or 20 weeks gestation and ending at 28 completed days. Still birth: the absence of signs of life at birth Neonatal death: Early neonatal death refers to death of a live born neonate during the first 7 days of life. Late neonatal death refers to death after 7 days but before 29 days of life.
Still birth rate: Number of stillborn neonates per 1000 neonates born, including live and stillbirths
Neonatal mortality rate: The number of neonatal deaths per 1000 live births
Perinatal mortality rate: The number of still births plus neonatal deaths during first 7 days per 1000 total births
NBU Total admissions in the month of July = 156 Total mortality in month of July = 77
ADMISSION TO NBU DIAGNOSIS NUMBER Percentage Prem + RDS 41 26.28 ASPHYXIA 27 17.31 Prematurity 22 14.10 Neonatal sepsis 12 7.69 RDS 29 18.59 MAS 2 1.28 Congenital anomalies 8 5.13 Mothers condition 9 5.77 Prematurity and NNS 2 1.28 NNJ 1 0.64 RD + Asphyxia 2 1.28 Asphyxia and sepsis 1 0.64 Total 156 100 Admission by weight Weight No % <1000 5 3.21 1000 - 1400 22 14.1 1500- 2499 55 35.26 2500 - 3999 70 44.87 >4000 4 2.56 total 156 100 MORTALITY BY GENDER Number Percentage Male 43 55.84 Female 34 44.16 Mortality Number Percentage Sepsis 17 23.61 RDS 4 5.56 ASPHYXIA 11 15.3 VLBW + RDS + PREM 21 29.17 RDS,NNS & PREM 5 6.94 PREMATURITY 7 9.72 ASPHYXIA + NNS 3 4.17 OTHERS 4 5.56 Total 72 100 Mortality Cases
CASE 1 XY. 36years Married businesswoman D.O.A 29/07/2011.. 4.40pm D.O.D 30/07/2011.14.45am
P2+0 G3 2psc LMP 4/11/2010 EDD 11/08/2011 GBD ~38/40 Presented with c/o labour pains Antenatal: attended KNH Profiles:- Hb 12.1 g/dl -Blood group A+ve -HIV/VDRL Non Reactive
Obs/Gyne Hx 2prev scar...2003 c/s .CPD..Lmi 3600gm A/W 2007 c/s.........Lmi 3600gm A/W O/E: Stable patient, No Pallor, vitals stable P/A Term, breech presentation, FHHR V/E: Cervix central, soft 3cm dilated. Plan: GXM, For emergency C/S Emergency C/S: at 11.00 pm. Intraop- 11.40..LMI extracted, Bwght 3200gm in frank breech. A/S , 7/1, 8/5, 9/10. admitted to nursery. 11.50pm:Patient UnresponsiveDuring Uterine repair.. Intubated , Resciscitation AttemptedNo Response. 12.45am Patient Confimed Dead. Cause of DeathAnaesthetic Complication.
Case 2 Patient Yz; DOA 22/7/11 DOD 25/7/11 28 yr old P1+0 Reffered From Mary help after Em C/s for severe Pet. Outcome Lfi 2200gm A/s 6/1, 7/5, 9/10 Post-op; Convulsed twice. Mgso4 started and patient reffered to Knh with a Bp of 200/150
KNH: 22/7/11... 8.00 am Ward round Postnatal Ecclampsia; No Convulsion in labor ward. Invx; U/e/c, Fhg....Urea 10, Cr 1130mmol/l, Hb 5.6g/dl Wbc ,13.3, Plateletets, 229ooo, Gcs 13/15 Plan; Gxm 3.0, Renal Review. 2.00pm; Urine Output < 20mls over 12hrs(admn time 2.00am) Input 4500mls Plan; Renal Review; Fresh blood.
8.45pm....Ward round Patient Convulsed... Started on iv Epanutin Awaiting renal Review and Fresh blood 23/7/11...4.30pm Renal Review; Ecclampsia/Aki Issues; Anuria, Raised Creatinine / Urea; Gcs 9/15 Plan; Triple Serology, Repeat U/e/c Renal Lab, Lasix 40mg, Transfusion; For Hemodyalysis 7.30pm Bp range 150/80-140/30mmhg; I/o..........? Awaiting FFPs, Physician Review. Phenytoin Iv 2.30am; Input 4500..Output .Nil Awaiting Results; Triple serology, Repeat U/e/c, Coagulation Profile, LFTs 24/7/11...6.30am Patient received 1.0 blood Repeat Convulsions 10/12hours Ros ; Gcs 15/15 Bp 120/80 Urine output Nil 9.45am; Renal Review... U/e/c results dont warrant dialysis; Recheck catheter; 4hourly U/e/c 12.10pm Hb 6.9g/dl Transfuse 3.0 blood Icu Review 3.45pm; Icu Review;...Ecclampsia. Aki Received 2.0 whole blood O/e Pale++, Edema,Gcs 14/15, OTPP; R/s Basal Crepitations, No Rhonchi ICU Plan; Urgent Dialysis; Add Phenorbabitone, BGAs, Restrict Fluid intake; Icu Admission When Bed is Available. 25/7/11; Followup- Time not indicated; Icu; Gcs 12/15. Bp 153/95 Repeat U/e/c; Cxr Urgent ICU admission; Intubation;BGAs 25/7/11; 5.00pm
Patient Unresponsive ; CPR unsuccessful Patient Confirmed dead 5.00pm Cause of death;.... Issues.... Delays on investigations; Transfusion; Dialysis; and Reviews Pt Ab, Para 1+ 1 DOA : 20/7/2011 DOD : 27/7/2011 Patient brought in at 10.30pm having delivered twins MSB at 19 wks. She was not communicating. Had retained placenta that was subsequently removed in labor ward. PMHX;Had been admitted and subsequently discharged on 17/7/2011 from GFB with hyperemesis gravidarum. She had been admitted with a month history of vomiting with inability to retain feeds and epigastric pain. Headaches,hiccups. No diarrhea/hob/urinary s/s,No ANC visit FSHX : Married, lives in huruma,business lady,No HTN,DM,Alcohol, smoking
O/E At Admission; Pale + Dehydrated,Jaundiced, T,36 degrees. RS: Clear CVS: Tachycardia. Bp 177/54 PA : 20/40 GENERALIZED ABDOMINAL TENDERNESS, Minimal lochia loss CNS: Neck soft, Kerning negative. Pupils Berl, 14/15
Imp: Endometritis + psychosis +dehydration 21/7 /2011 : sick looking 6/15, groaning with eyes wide open. RS:: CLEAR; input 2700 output 300: urea 23.6, creatinine 450,Na+ 129, k+ 3.0 Imp AKI + Sepsis Planned for dialysis, rocephin and flagyl prescribed. 11.30PM : GCS 8/15 Diagnosed as hepatic encephalopathy 12noon: Gcs 6/15, developed right sided twitching, febrile,tachycardia 120bpm WBC: 16.6,NEUTROPHILS 13.3,HB 4.43, PLTS 132,UREA 20.9,CREAT. 436,K+ 2.4,CL 83, NA+ 127. Diagnosis of Uremic encephalopathy.