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Myoma
Presented by:
Abu, Camile
Granada, Glyde Pebbles
Landicho, Katrina
Linatoc, Jeanne Lyn
Luza, Ailen
Maralit, Ma. Krishna
Sim, Khay
Ulan, Darlene
Umali, Marianne Lyn
Avena, Gaudencio
Dimaculangan, Argenald Joseph
Hernandez, Michael Franklin
INTRODUCTION
Uterine myoma is the most common tumors of
the female genitalia tract. Myoma commonly called
fibroid. It is the benign tumor of the smooth muscle in
the wall of the uterus. Hysterectomy has been a
common therapy in patients who have completed
reproduction. Total hysterectomy plus unilateral
salphingo oophorectomy TAHBSO- this procedure
removes the utereus, cervix, one ovary and one
fallopian tube, while one ovary and one fallopian tube
are left in places.
Fibroids can be present and be apparent. However
they are clinically apparent in up to 25 % of the
women. Although, myoma is generally considered to
be slowly growing tumor in 20-40% of women at the
age of 35 and more have uterine fibroids of
significant sizes with severe clinical symptoms.
Moreover, myoma can be relapse in 7-28% of patient
after surgical treatment and in certain case it may
even turn to malignant tumor, this could causes
significant morbidity including prolonged or heavy
menstrual bleeding, pelvic pleasure and pain and in
rare cases reproductive dysfunction. Myoma affects
one of every four women ¾ of woman with this
condition,however, experience no symptoms.
Uterine myoma is developing on the background of hyper
estrogen, progesterone, deficits in hyper gonodotrophine.
The majority of the researches say that the growth of
myoma depends on concentration of cystosolic receptors to
the sex hormones and their interactions, with the endrogen
or extrogen hormones. In accordance to clinical
observations, it can be admitted that both growth and
regressions of myoma are estrogen-dependent, is the tumor
size gets increased during pregnancy and is regressed after
menopause. The only that needs to clear is to find out
whether it is decreased in receptors numbers of estrogen,
progesterone and androgen- hormones quantities which
lead to regression in myoma size ( regarding androgen there
is an hypothesis that myoma is sensitive to androgen ) for
growth that formed tumors, the need to be further supported
by negative factors.
Abortions, long term used of inadequate contraceptive
pills, chronic sub-acute and acute inflammation of uterus
or its appendices, stress, ultraviolet radiation, cystic
formation of ovary etc. for example, the woman who had
ten abortions by the age of thirty have double to
developed uterine myoma at fourty years old. In fact,
uterine myoma = account for 20% of 650,000
hysterectomies performed annually in the U.S interest in
the uterine preservation and organ preserving surgery
through techniques minimally invasive surgery has
increased the first reports of laparoscopic myomectomy.
PATIENT’S PROFILE