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Atoms
Molecules
Macromolecules
Cellular structures
Cells
Electrons (-)
In orbits (shells)
around the nucleus)
In a pure state, an
elements number of
protons (+) and
electrons (-) are equal
and cancel their charges
Weaker bonds
Hydrogen bonds
Others
Covalent bonds
Sharing of electrons
in the outer shells
Share 2 - single bond
Share 4 - double
bond
Some elements pull
the electrons more
to them
(Electronegativity)
Uneven sharing
(not very) polar covalent
Uneven sharing
polar covalent
Even sharing non polar covalent
Hydration
shell
Hydrophilic
Hydrophobic
Proteins
imbedded
in a
membrane
(Ch 7 fig)
pH
Water
dissociates and
forms an
equilibrium
Proton (H+)
pH
Acids increase?
H+
(acids may also
decrease OH-)
Bases increase?
OH (bases may also
decrease H+)
This leads to
A tremendous diversity of
shapes of carbon compounds
This leads to a great diversity of function
Polymers (Macromolecules)
I. Carbohydrates
Polymers of sugars
Monosaccharide
(simple sugar)
Hydroxyl groups
and 1 carbonyl
Formula (CnH2nOn)
Aldose vs Ketose
Glucose (C6H12O6)
is an important
building block
Glycogen
Storage
Cellulose
Structural
Glucose monomers
Glucose monomers
C6H12O6 + C6H12O6
H2O
II. Proteins
Amino acids (monomer) >>> Peptides
Peptides >>> Polypeptides
Polypeptides >>> Proteins
Functions of proteins
Carboxyl group
Acid (proton donor)
R group
Affect shape and
functionality
There are 20
different amino
acids
(with 20 different
R groups)
Primary structure
Linear chain of amino acids
Secondary structure
Hydrogen bonds stabilize regions of chains
helix and pleated sheet
Tertiary structure
3-D shape stabilized by side chain interactions
Quaternary structure
Association of 2 or more polypeptides
(some proteins only)
4 identical
polypeptides
4 polypeptides
2 different polypeptides
Function
Store and transmit hereditary
information
Phosphate group
Nitrogenous base
One of 4
1 difference between DNA and RNA
Phophodiester bonds
IV. Lipids
Not polymers
Diverse group of hydrophobic
molecules
a) Fats
b) Phospholipids
c) Steroids
a) Fats
Function in
storage (C and
NRG), insulation,
padding
Glycerol + 3 fatty
acids
Ester linkage via
a dehydration
synthesis (again!)
Saturated
v.
Unsaturated fats
b) Phospholipids
Hydrophilic
head
Glycerol
Phosphate
Choline
2 Hydrophobic
tails
Fatty acid
chains
Chapter 6
c) Steroids
Cholesterol (a membrane component in animal
cells)
Hydrocarbon chain
Hydrocarbon rings
(Chap 7 fig)
c) Steroids
Steroid hormones
Testosterone
Estrogen
Emergent properties
Atoms
Weve done this!
Molecules
Macromolecules
Cellular structures
On to cells!
Cells