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What is Biochemistry ?
B.
Principles of Biochemistry
Cells
Basic building blocks of life
Smallest living unit of an organism
Grow, reproduce, use energy, adapt, respond to their environment
Many cannot be seen with the naked eye
A cell may be an entire organism or it may be one of billions of
cells that make up the organism
Basis Types of Cells
Water
About 60-90 percent
of an organism is water
Water is used in
most reactions in
the body
Water is called
the universal
solvent
8
III. Macromolecules
A. What are they?
1. __________________________________
Very large molecules that
make most of the structure of
_______________________________________
the body
2. Made
of smaller piecesmonomer
called
s
__________ that can be assembled
like
legos to form a variety of structures. A
polymer
large
chain of monomers is called a
_________.
III. Macromolecules
B. Carbohydrates
1. Monomer: ____________________
monosaccharide
(sugar)
2. Polymer: _____________________
polysaccharide
rings of carbon
3. Structure:______________________
(starch)
oxygen and hydrogen
attached;
with
________________________________
CHUses:
energy, plant
4.
2O
___________________
structure
5. Examples:
________________
sucrose, cellullose
Examples of Carbohydrates
III. Macromolecules
C. Lipids
1. Monomer: __________
fatty acid
lipid or fat
2. Polymer: ___________
3 long chains of
3. Structure:______________________
________________________________
hydrogen oncarbon
a glycerol
molecule
4.
Uses: ________________________
energy, structure,
5. Examples:
____________________
fat, oil,
warmth
cholesterol
Examples of Lipids
III. Macromolecules
D. Protein
1. Monomer: _______________
amino acid
protein
(20) or
2. Polymer: _____________________
polypeptide
central carbon atom
3. Structure:______________________
with carboxyl, & R
________________________________
hydrogen, amine,
4.
groups
Uses: ________________________
structure, emergency
skin, insulin,
5. Examples:
energy
____________________
enzymes
Examples of Proteins
III. Macromolecules
E. Nucleic Acids
1. Monomer: _______________
nucleotide (5)
nucleic acid
2. Polymer: ___________
5-carbon sugar
3. Structure:______________________
attached
to nitrogen base
and phosphate
________________________________
group
4.
Uses: ___________________
stores genetic code
DNA and RNA
5. Examples: _______________
IV. ATP
A. ATP stands for adenosine
_____________________
triphosphate
B. Cells use ATP as
arechargeable
__________________
3___ phosphates
battery
C. Made of adenine with
D. Lots of energy is stored in the bond
the second and third
between _____________________________
E. When phosphates
this bond is broken,
tremendous energy is released.
F. The pieces are then reassembled,
storing more energy for another use.
Examples of ATP
V. Enzymes
A. Special proteins
that speed chemical
reactions
1. Chemical reactions
activation
require a energy
certain
_______________ to get
started.
2. Enzymes decrease
this energy, making
reactions occur faster.
V. Enzymes
B. Lock-and-Key Model
1. Enzymes are not used up by the
reaction, but each can only work on one
enzyme
reaction
(________________).
2.specificity
This is called the lock-and-key model
kelike a _____
of enzymes. An enzyme is
which can openlock
exactly one
y _____. If you
want to unlock another reaction, you
need a different enzyme.
V. Enzymes
V. Enzymes
C. Factors which affect enzymes
1.Temperatur
_____________--enzymes, like all
proteins,
change shape when exposed
e