Complete Blood Count

1. RBC : RBC Count, Hb, Hct, RBC

indices (MCV, MCH, MCHC )
2. WBC : WBC Count, WBC
Differential.
3. Platelet : Platelet Count, MPV.
PDW

Procedure

Hematocytometer

RBC Count
Normal
Values
Adult Females
: 4.0-5.5
mill/L
Adult Male :
4.5-6.2
mill/L

RBC indices (MCV, MCH, MCHC, RDW)

Mean corpuscular volume (MCV) is a
measurement of the average size of a
single red blood cell.
Mean corpuscular hemoglobin (MCH) is a
calculation of the average amount of
hemoglobin inside a single red blood cell.
Mean corpuscular hemoglobin
concentration (MCHC) is a calculation of
the average concentration of hemoglobin
inside a single red blood cell.

 The Mean Cell Volume (MCV)

Normal Values
Adults 7696 fl.
MCV is reduced in microcytic anemias
MCV is raised in macrocytic anemias
The Mean Cell Hemoglobin (MCH)
Normal MCH in adults is from 27 to 32 pg.
MCH is reduced in hypochromic anemias.
The Mean Cell Hemoglobin Concentration (MCHC)
3135 g%

This too, is low in hypochromic anemias.

Interpretasi
Low MCV : Indicates RBCs are smaller
than normal (microcytic); caused by
iron deficiency anemia or
thalassemias, for example.
High MCV : Indicates RBCs are larger
than normal (macrocytic), for
example in anemia caused by
vitamin B12 or folate deficiency, liver
disease, hypothyroidism

WBC Count
In the total leukocyte count, the reference
interval for adults is 4.511.0 10 9/L.

Concise Book of Medical Laboratory Technology: Methods and

WBC Differential

Pathway for differential cell coun

Normal Values ( Adult)

Neutrophil (segs) : 54-62%

Neutrophil (bands) : 3-5%
Eosinophils : 1-4%
Basophils : 0.75%
Monocyte : 2-10%
Lymphocyte :20-40%

Concise Book of Medical Laboratory Technology: Methods and Interpretations

Interpretasi
Type of Cell
Increase
Decrease
White Blood Cells (WBC):
leukocytosis
leukopenia
lymphocytes lymphocytosis
lymphocytopenia
granulocytes: granulocytosis
granulocytopenia or
agranulocytosis
neutrophils neutrophilia neutropenia
eosinophils eosinophilia eosinopenia
basophils
basophilia
basopenia

Interpretasi
Neutrophil granulocytes: May indicate acute bacterial
infection. May also be raised in acute viral infections.
Lymphocytes: Higher with some viral infections such
as glandular fever
Monocytes: May be raised in cronic bacterial
infection, tuberculosis, malaria,
Eosinophil granulocytes: Increased in parasitic
infections, asthma, or allergic reaction.
Basophil granulocytes: May be increased in bone
marrow related conditions such as leukemia or
lymphoma

Platelet Count
Reference values for platelet counts
are 150450 109/L.

Concise Book of Medical Laboratory Technology: Methods and Interpretations

Interpretasi
Thrombocytopenia: Viral infection
(mononucleosis, measles, hepatitis),
Platelet autoantibody, Drugs
(acetaminophen, quinidine, sulfa drugs),
Autoimmune disorders, Chemo or
radiation therapy
Thrombocytosis: Cancer (lung,
gastrointestinal, breast, ovarian,
lymphoma), Iron deficiency anemia,
Hemolytic anemia

Mean platelet volume (MPV) : It is a calculation of the

average size of platelets.

Reference values for MPV are approximately

6.512 fL in adults.
Low Result : Indicates average size of platelets is
small; a low MPV may mean that a condition is
affecting the production of platelets by the bone
marrow.
High Result : Indicates a high number of larger,this
may be due to the bone marrow producing and
releasing platelets rapidly into circulation.

 Platelet distribution width (PDW) : It

reflects how uniform platelets are in
size.