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Dermatology
Nyoman Suryawati
Bagian/ SMF IKKK FK UNUD
Epidemiology
In the western : prevalence has been estimated at
affected.
begin within
during the
years of age.
Th1/Th2 Paradigm
Cell-mediated immunity
IL-2
Th1
IL-12
TNF
IFN
IL-10
Th0
Humoral immunity
IL-4
IL-12, IFN
IL-4
Th2
IL-5
IL-10
lichenification
Areas of perspiration
Acute Stage
Pruritic, erythmatous, excoriated
papules with extensive serous
exudate superimposed on a
background of erythema
Chronic Stage
Repeated excorations and
trauma lead to chronic
lescharacterized by thickened
plaques with increased marking
ions (lichenification) and dry,
fibrotic papules
Kriteria Diagnosis
Hanifin & Lobitz
Hanifin & Rajka
Svenson
William
Pruritus
Morfologi & distribusi yang khas
Kronik- residif
Stigmata atopik dalam keluarga
Xerosis
Hiperlinearitas palmar
Ig E meningkat
Kheilitis
Mudah terjadi infeksi
Pitiriasis alba
White dermographism
Uji kulit positif
Kepucatan wajah
Faktor emosi
2.
Fisura periaurikuler
4. Keratosia pilaris
6. Dermatitis tanga
8. Dermatitis Scalp
10. Keratosis pilaris
12. Dermatitis niple
14. Katarak/keratok
16. Garis Dennie-Mo
18. Awitan dini
20. Tanda Hertog
Treatment
The management of ICD can be divided into treating the active case and
prevention. Topical corticosteroids, soap substitutes, and emollients are
widely accepted as the treatment of established contact dermatitis.
Second line treatments such as topical PUVA, azathioprine, and
cyclosporin are probably widely used for steroid resistant chronic hand
dermatitis.
Mechanism of Type IV
Hypersensitivities
Treatment ACD
The only available etiologic treatment of ACD is
elimination of the contact allergen.
Systemic
Antihistamine
Corticosteroid
Topical
Acute phase (papulo-vesiculo, oozing) wet
bandage
solutio NaCl 0,9 %
Chronic phase topical steroid
Nickel
Chromate
Cosmetics and skin care products
Drug dermatitis
Plant dermatitis
Clinical Features
Major subjective symptoms
History of sufficient exposure to a cutaneous irritant
Onset of symptoms within minutes to hours of exposure in simple
acute irritant contact dermatitis.
The onset of signs and symptoms may be delayed by weeks in
cummulative irritant contact dermatitis.
Pain, burning, stinging or discomfort exceeding pruritus early in the
clinical course