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DE CANCEROLOGA
Gammagrafa
sea en
Procesos
Benignos
UVI CANCINO RAMOS R1MN
COORDINADORA: DRA. LUCERO ABUNDIZ LPEZ
Osteodistrofia Renal
Espondilitis Anquilosante
Artritis Gotosa
Enfermedades Metablicas
Osteoartritis
Enfermedad de Paget
Osteoporosis
Osteomalacia y Raquitismo
Calcificacin Distrfica
Hiperparatiroidismo
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Sndrome Doloroso
Regional Complejo
Sndrome Clnico
Osteopenia Regional
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Dolor
Sensibilidad
Desgaste
tejido
subcutneo y
msculo
Prdida de
color con piel
fra
Distrfica 20-60 se
Dolor
Rigidez
Sensibilidad
Edema
articular
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Displasia Fibrosa
Benigna, del desarrollo y no heredada,
alargamiento y deformidad de hueso
involucrado
Monosttica (70-80%)
Poliosttica (30%)
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Displasia
Fibrosa
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Displasia Fibrosa
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Clasificacin de Fracturas
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Huesos
pequeos de
manos y pies
Fracturas por
estrs
Sx de nio
maltratado
Consolidacin
Retardada
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Fracturas
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Fracturas
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Espondilolisis
coronal
Transaxial
Sagital
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Curacin
de Fracturas
Formacin
de
Hematoma
Formacin de
Callo
Remodelacin
Invasin de
Tejido de
Granulacin
(48h)
Formacin de
Procallo
Modelado
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedades Metablicas
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedades Metablicas
Recambio seo
Concentracin Ca en hueso
Captacin
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
Zonas Templadas
50a 3-4%
Asintomtico 90%
Viral?
80a (10%)
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
Osteoblasto infectado:
IL6 resorcin sea
Activacin de Protooncogenes C-Fos
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
Predominio MO Roja
Reemplazo por tejido conectivo fibroso
Act. Osteoblstica y Osteoclstica:
Hueso esclertico
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
Fase 1 (Ltica)
Resorcin activa y excesiva (Ltica)
Ablandamiento seo
Trabculas delgadas e irrigadas
Fracturas de tibia y fmur
GO ms sensible 15-30% ms que en Rx
Fase 2 (Mixta)
Formacin y Resorcin acelerada
Osteoblastos y Osteoclastos
Vascularidad de tejido seo, nuevo hueso
Trabcula gruesa y desorganizada
Fase 3 (Blstica)
Esclertica
Patrn mosaico desordenado de lminas espesas
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
Rx:
Osteoporosis circunscripta
(osteolticas en crneo)
Triada Patognomnico
Expansin sea
Engrosamiento Cortical
Engrosamiento Trabecular
http://www.radiologyassistant.nl/bonetumors
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
Captacin
Afectacin difusa al hueso
nfasis en estructuras anatmicas
Extremos de huesos largos afectados
Expansin sea
Deformidad
Cambio gradual a travs de los aos
Poliosttica 80%
Vertebras y Pelvis ms afectadas
Resorcin y Formacin sea anormal y
excesiva
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Signo
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Signo
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
COMPLICACIONES
Dolor seo
Deformidades seas
Fracturas (incremento convexidad)
Osteoartritis secundaria
Neurolgicas (Compresiones)
Neoplsicas (Sarcoma)
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Enfermedad de Paget
Ostetis Deformans
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteoporosis
Osteoporosis
Trabecular 50%
Cortical 30%
30% Total
50% Total
(90% casos
postmenopusicas)
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteoporosis
4 meses
2 aos
Formacin sea
retardada
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteoporosis
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteoporosis
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteoporosis
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteomalacia y Raquitismo
Causas de Osteomalacia
Poca exposicin a luz solar o baja ingesta de
vitamina D
Metabolismo Anormal de Vitamina D (IRC)
Malabsorcin de Vit. D (Enf Celiaca)
Resistencia Perifrica a vitamina D
Hipofosfatemia (Ligada al X)
Inhibicin de la mineralizacin (Floruro de
Sodio)
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteomalacia
y Raquitismo
Causas de Osteomalacia
Poca exposicin a luz solar o baja ingesta de
vitamina D
Metabolismo Anormal de Vitamina D (IRC)
Malabsorcin de Vit. D (Enf Celiaca)
Resistencia Perifrica a vitamina D
Hipofosfatemia (Ligada al X)
Inhibicin de la mineralizacin (Floruro de
Sodio)
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteomalacia y
Raquitismo
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteomalacia y
Raquitismo
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteomalacia y
Raquitismo
Debilidad Muscular
Hipocalcemia
Pseudoartrosis
Marcha de pato
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Hiperparatiroidismo
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Hiperparatiroidismo
SITIOS MS COMUNES DE
PSEUDOFRACTURAS
Costilla
Fmur
Pelvis
Escpula
Antebrazo
Tibia
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteodistrofia Renal
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteodistrofia Renal
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteodistrofia
Renal
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Espondilitis Anquilosante
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Espondilitis Anquilosante
Artritis Gotosa
Sntesis
de
Purinas
cido
rico
Excrecin
lenta de Urato
por
Reabosorcin
Urato
FG Urato
Eliminaci
n renal
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Artritis Gotosa
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Artritis Gotosa
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteoartritis
Manos, muecas
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteoartritis
Prdida Gradual de
Hueso articular
Engrosamiento y
Esclerosis de Hueso
debajo de cartlago
Formacin de
osteofitos
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Osteoartritis
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
DISTRFICA
HETEROTPICA
MESTASTSICA
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Calcificacin Distrfica
Tejido Necrtico
Ignac Fogelman,Susan Clarke,Gary Cook,Gopinath Gnanasegaran, Atlas of Clinical Nuclear Medicine, Third Edition, CRC Press 2014.
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Calcificacin Metastsica
4-12 s postrauma
Benigna 80%
Incidencia variable,
mecanismo de dao
depende
de
Benigna 80%
Elgazzar, A. H., & Kazem, N. (2015). InThe pathophysiologic basis of nuclear medicine. Springer International Publishing.
Normaliza al ao
GRACIAS