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What is Breast Cancer?
Common sites of
metastases:
Risk factors:
– Age
– Family history
– Early menarche, late menopause
– Previous cancer of the breast, uterus,
ovaries
– Nulliparity, late first birth
– Obesity
– High – dose radiation exposure to the
breast
Signs and Symptoms:
• -mass/lump felt
• -upper quadrant
beneath nipple
or axilla
• -fixed, irregular
noncapsulated
mass; typically
painless except in
later stage
Signs and Symptoms:
Signs and Symptoms:
• The breast is
composed of:
– milk glands
(lobules)
– Milk ducts
– nipple
– areola
– connective (fibrous)
– fat
Pathophysiology:
• Predisposing • Precipitating
factors factors:
– Age – History
– Gender – of abnormal
– Late breast
Menopausal – biopsies
Neoplasm formation in the breast
It Becomes systemic
Pathophysiology:
• Primary cancer
spreads
• if treated: If not treated:
– surgery
Breast cancer spreads to major
– radiotherapy organs
– chemotherapy
– Interstitial laser
thermotherapy Compromise
the functions
Removal ofBreast Tissure of the major
organs
Cancer Cell
Destroyed DEATH
Diagnostic Test
• Medications: Tamoxifen
(Nolvadex)
• for estrogen receptor-positive
tumors
•
•
• exogenous administration of
steroid hormones, which
inhibit the production or
• Hormonal manipulation activity of such hormones
therapy • Changes the levels or activity
– Use of medication in that causes certain cancers
postmenstrual to cease growing
women
Surgical interventions:
• Lumpectomy • Simple
mastectomy
•
Surgical interventions: