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Lai Limson
Golveo
Tabora
Vasquez
Masa Kawaguchi
Clinical Manifestations:
Ruddy Complexion
Splenomegaly
Increase Bp
Increased Uric Acid
Pruritus
Erythromyalgia
Headache
Dizziness
Tinnitus
Fatigue
Paresthesias
Blurred vision
Angina
Claudication
Dyspnea
Thrombophlebitis
Medical Management:
Phlebotomy
The use of chemotherapeutic agents (Hydroxyurea) can
be used to suppress marrow function.
Patients receiving hydroxyurea appear to have a
lower incidence of thrombotic complications than
those treated by phlebotomy which may result in a
normal platelet count.
Anagrelide(Agrylin)
Interferon alfa-2b(Intron-A)
Allopurinol(Zyloprim)
Aspirin
Anagrelide(Agrylin)
Inhibits platelet aggregation and can be useful in
controlling the thrombocytosis associated with
polycythemia vera.
Side effects:
Headache
Fluid retention
Cardiac dysrhythmias
Heart failure
Interferon alfa-2b(Intron-A)
Most effective treatment for managing the
pruritus associated with polycythemia vera.
Side Effects:
Flulike Syndrome
Depression
Allopurinol(Zyloprim)
Is used to prevent gouty attacks in patients with
elevated uric acid concentration.
Aspirin
Is also useful in reducing the pain associated
with erythromyalgia.
Nursing Management
Assessed the risk factors for thrombotic
complications, particularly smoking, obesity,
and poorly controlled hypertension.
Patient should be instructed about signs and
symptoms of thrombosis.
To reduce likelihood of DVT:
Sedentary behaviour, crossing the legs, and
wearing of tight or restrictive clothing
(Particularly stocking) is discouraged.
Nursing Management
Patients with history of significant bleeding are
advised to avoid aspirin and aspirin-containing
medications, because these medications alter
platelet function.
Advised patient to minimised alcohol intake to
further diminished the risk of bleeding.
Nursing Management
Instruct the patient to take iron supplements,
because iron can further stimulate RBC
production.
For Pruritus:
May recommend bathing in tepid or cool water and
avoiding vigorous towelling off after bathing.
Cocoa butter/oatmeal-based lotions and
bath products or baking soda dissolved
in bath water may also be effective.