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Gastrulation
Formation of embryonic mesoderm and endoderm
Primitive streak on the surface of the epiblast
The cephalic end of the streak,known as primitive node
Primitive node surrounds the a small primitive pit
Primitive streak
Day 14 -15 raised groove appears
on dorsal surface of the epiblast
cells migrate inward at the streak,
displacing underlying hypoblast to
become the endoderm
Day 16 ingressing epiblast cells
form the mesoderm (a new layer
between the epiblast and
endoderm)
Epiblast cells that remain on the
embryos dorsal surface make up
the ectoderm
Ectoderm & endoderm = epithelia
Mesoderm = mesenchyme tissue
(mesen=middle; chyme=fluid)
Formation of notochord
Cells invaginating the primitive pit Move straight
forward in cephalic direction upto prochordal plate.
Form a tube like process known as notochordal or
head process.
By the 18th day,floor of the
notochordal process fuses with
underlying endoderm
Lumen of the notochordal
process disappears completely
Notocordal process forms a
narrow plate of cells
Notochordal cells proliferate
and forms solid cord,known as
definitive notochord.
Tertiary villi
The end