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FAKULTAS KEDOKTERAN
JOURNAL READING
JUNI 2016
UNIVERSITAS PATTIMURA
Disusun Oleh:
ASEP BUDIYANTO
(2010-83-020)
Pembimbing:
of Medicine and
Respiratory
Medicine
Specialist.
Tobacco Master's Degree,
Master in Management and
Health Management, Master
in Pulmonary Hypertension
Thrombotic and Master in
Pathology.
Head of Section in the
Service of Pneumology of
the
Hospital
General
Universitario
Gregorio
Maran.
Member of the National
Commission of Pneumology,
Resident Tutor specialty and
Associate
Professor
of
Medicine
at
the
Complutense University of
Madrid.
Abstract:
Chronic obstructive pulmonary disease (COPD) is commonly
associated with heart failure (HF) in clinical practice since
they share the same pathogenic mechanism
Cont,,
Statins, ACE inhibitors, and ARB may reduce the morbidity and
mortality of COPD patients. Caution is advised with use of
inhaled 2-agonists for the treatment of COPD in patients with
HF.
Noninvasive ventilation, added to conventional therapy,
improves the outcome of patients with acute respiratory failure
due to hypercapnic exacerbation of COPD or HF in situations of
acute pulmonary edema
Introduction
Pathophysiology
Inflammation is itself
implicated in the
pathogenesis of HF
10
11
Diagnosis
ECG
Chest
radiography
Echocardiogra
phy
14
Plasma levels
of natriuretic
peptides
Pulmonary
function tests
Therapy
Pharmacological treatment for HF that
influences COPD patient prognosis
2-blocker;cardioselectif metoprolol, bisoprolol,
and nebivolo
Statins, ACE inhibitors, ARBsreduce the morbidity
and mortality of COPD patients
DiureticsHigh
risk
of
kidney
dysfunction,
morbidity, and mortality.
A recent study only 22% patient HF with COPD
prescribed -blockers, as opposed to 81% of those
without COPD. Prescription of ACE inhibitors and
ARBs,
where no significant difference. Most COPD
15
patients were prescribed aldosterone antagonists
corticosteroids
have
16
the
outcome
of
patients
with
acute
respiratory failure
improves gas exchange and symptoms,reducing the
need for endotracheal intubation, hospital mortality,
and hospital stay.
In acute cardiogenic pulmonary edema, accelerates
the remission of symptoms and the normalization of
blood
gas
parameters,
reduces
the
need
for
17
endotracheal
intubation, and is associated with a
Summary
The
Caution is
beneficial
advised
NIV
effects of Statins, ACE
with use of
improves
cardioselect inhibitors,
and ARBs
inhaled 2the
ive 1may reduce agonists for outcome of
blockers
the
the
patients
should not
morbidity
treatment
with acute
be denied
and
of COPD in respiratory
in stable
mortality.
patients
failure
patients
with HF
18
Conclusion
COPD is commonly associated with HF in clinical
practice. Incur significant morbidity and mortality.
Perform an integrated approach to objectively
identify both diseases at an early stage, and to
optimize control of respiratory and cardiovascular
conditions
Additional studies providing new data on the
pathogenesis and management of patients with
19