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Amino Acid
Structure
Abigail Jopling
Biochemistry
Objectives
Identify
Define
Characterize
Describe
Name
Biochemistry
Biochemistry
Tetrahedral carbon is
chiral (except in glycine)
Size
Shape
Charge
H bond
Hydrophobic character
Chemical reactivity
Source
Biochemistry
Source
Stereochemical
Projection
Source
Biochemistry
Dipolar
ions/Zwitterion
L vs D
Biochemistry
L vs D
Biochemistry
Zwitterion
Biochemistry
10
Zwitterion
Biochemistry
11
Alanine Titration
Sourc
e
Biochemistry
12
Alanine Titration
Biochemistry
13
Biochemistry
Nomenclature
Each
14
Biochemistry
Size
Shape
Charge
Hydrogen bond
Acid/Base
15
Biochemistry
Polar
Positively
Negatively
16
Biochemistry
Nonpolar R Groups
Hydrophobic
amino acids
Tend
17
Nonpolar R Groups
Biochemistry
18
Biochemistry
19
Biochemistry
20
Acidic R Groups
Negatively
charged at neutral pH
Biochemistry
21
Acidic R Groups
Biochemistry
22
Biochemistry
Basic R Groups
Positively
charged at neutral pH
Histidines
Important
23
Basic R Groups
Biochemistry
24
Histidine Ionization
Biochemistry
25
4-hydroxyproline
5-hydroxylysine
-N-methyl-lysine
3-methylhistidine
-carboxyglutamate
desmosine
isodesmosine
Biochemistry
26
Biochemistry
Post-Translational Modifications
27
Biochemistry
28
Kawashiorkor
Disease
of the displaced
child
Inadequate
intake disrupts
oncotic pressure
Reversible
if treated early
Biochemistry
29
Biochemistry
Acid/Base Properties
Amphoteric
Acid-base
catalysis
30
Biochemistry
31
Biochemistry
Peptide Bond
32
Biochemistry
Sourc
33
Biochemistry
34
Polypeptide Formation
Source
Biochemistry
35
Biochemistry
direction
Naming
36
Biochemistry
Polypeptide Directionality
37
Biochemistry
38
Putting It All
Together
Biochemistry