Académique Documents
Professionnel Documents
Culture Documents
Staphylococcus aureus
Staphylococcus aureus
Harmless to most carriers
Between 30% and 40% carry staph on
skin or in noses
Staphylococcus aureus
In otherwise healthy people, some
strains of staph can cause minor skin
eruptions
Staphylococcus aureus
Some staph bacteria have developed
resistance to antibiotics
About 1% carry drug-resistant strains
of staph
MRSA, VRSA
Staphylococcus aureus
People with weakened immune
systems
high risk of staph-caused pneumonia,
sepsis, or infections of surgical wounds
Antibiotics
Recall: Antibiotics kill bacteria or slow
growth by interfering with essential
bacterial cell structures
Acquiring resistance
How does this happen??
EVOLUTION.
random mutations
new alleles
genetic diversity
Acquiring resistance
Bacteria
reproduce
asexually by
binary
fission
Acquiring resistance
Each time DNA is replicated, there is a
chance for genetic mutations
-- alleles carried into daughter cells
Rapid reproduction
-- high rate of mutation
accumulation
Acquiring resistance
A bacterium can also acquire new
alleles by gene swapping with other
bacteria
Stopping superbugs
Because the use of antibiotics can drive bacterial
populations to evolve resistance, antibiotic resistance is
inevitable. The best way to control resistance is to
change practices that enable resistant strains to thrive.