Control of the Cell Cycle

Cyclins
Cell cycle is controlled by proteins called
cyclins and a set of enzymes that attach to
the cyclin and become activated.
The interaction of these molecules is based on
conditions within and outside the cell.

Enzyme Production
Enzyme production is directed by genes
located on chromosomes.
A gene is a segment of DNA that controls the
production of a protein.
Several enzymes trigger DNA replication at the end
of interphase.

Cancer
Malignant growth resulting from
uncontrolled cell division.
Uncontrolled division can result from failure to
produce certain enzymes, overproduction of
enzymes, or production of enzymes at the
wrong times.

Cancer
Cancerous cells form masses of tissue
called tumors that deprive normal cells of
nutrients.
In later stages, cancerous cells enter the
circulatory system and spread throughout
the body in a process called metastasis.
The result of this process is the formation of
new tumors in other organs and organ systems.

Cancer
Currently the second leading cause of death
in the U.S. (first is heart disease)
May affect any tissue in the body.
In the U.S., lung, colon, breast, and
prostrate cancers are the most prevalent.

Cause of Cancer
Currently, scientists consider cancer to be a
result of changes in one or more genes that
produce substances that are involved in
controlling the cell cycle.
These changes are expressed as cancer when
something prompts the damaged genes into
action.

Cause of Cancer
Influenced by both genetic and
environmental conditions, such as smoking,
exposure to UV radiation, air and water
pollution, and diet.

Prevention of Cancer
Only current measure of prevention is a
healthy lifestyle, including diet.