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The Histology of Female

Genital System
I Wayan Sugiritama

Medical Faculty of Udayana University.

Medical Faculty of Udayana University


2008

Overview
Internal Genetalia :

Paired of Ovaries
Paired of Oviduct
Uterus
Vagina

External Genetalia:
Labia Majora
Labia Minora
Clitoris

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OVARIES

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PRIMORDIAL FOLLICLE

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FOLLICULAR GROWTH
PRIMORDIAL F.
(formed during fetal life)
Follicular
Growth

PUBERTY

Primary F.
Secondary F.

Mature F.
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Modification of :
Oocyte
Granulosa cells
Stromal fibroblast

PRIMARY FOLLICLES

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SECONDARY FOLLICLE

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THECA INTERNA & EXTERNA

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GRAAFIAN FOLLICLE

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OVULATION PHASE
Day 14 of menstrual Cycle

LH surge

Rupture the wall of G.F

PG, Histamine,Collagenases
Hyaluronic acid

Complete the 1st meiosis


Release of secondary oocyte

(arrest in metaphase II) with corona


radiata

Received the oocyte by


fimbriae

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CORPUS LUTEUM/C.L. (LUTEAL PHASE )

Theca lutein
cells

Granulosa
lutein cells

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FATE OF CORPUS LUTEUM ??


DEPEND ON WHETHER
PREGNANCY IS
ESTBALISH OR NOT :
If the pregnancy does not
occur C.L. degenerate
CORPUS ALBICANS
If pregnancy occur hCG
maintains C.L C.L. of
pregnancy secrete
hormone maintain
pregnancy

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C.L. Gravidarum

CORPUS ALBICANS
C.L of menstruation is
invaded by
fibroblasts fibrotic.
Fibrous connective
tissue corpus
albicans
Persist as the scar on
the surface of ovary

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UTERUS

The Walls of uterus :

Endometrium

Myometrium

Serosa/adventitia
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UTERUS

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Menstrual Cycle

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Two layers (zone) of Endometrium


Functionalis
Thick, superficial (surface
epith., lam. prop., & gland)

Rich capillary network (coiled


arteries)
Sloughed at menstruation

Basalis
Deep, narow (lam. prop., &
gland)

straight arteries
Regenerate functionalis
layer each mentrual cycle

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Proliferative/follicular phase (days 5-14)

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Secretory / Luteal phase (days 15-28)

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Menstrual phase (days 1-4)

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OVIDUCTS (Fallopian Tubes)

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Oviducts (Fallopian Tubes)


Two types epith. Cell :
Ciliated cells
Cilia beat
toward the
uterus

Non ciliated
peg cells
No cilia
Secretory :

Nutritive &
protective for
oocyte
capacitation of
sperm.

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CERVIX
Epithel :
Lumen : mucus-secreting
simple columnar epith.
External surface : stratified
sq. nonkeratinized epith.
Wall :
dense, collagenous cont.
tissue
Cervical glands regulates by
progesteron
Serous/watery fluid :
around the time of
ovulation
viscous/mucus : at
pregnancy/luteal phase of
menstruation
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VAGINA

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Mammary Glands
Consist of 15-25 lobes of comp.
tubuloalveolar gland
Excretory lactiferous duct
Dense C.T. & adipose tissue
separate the lobes
Histologic structure varies
according to :
Age
Physiologic status

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The Mammary Glands

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Figure 28.23a-c

MATUR SUKSMA

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