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BRAI
N
MAKER
Absence of
GI
complaints
Gut health
in
early life
Optimal
nutritional
status and
development
Wellbeing and
strong parental
bonding
Serotoni
Gastrointestin
n
al health
BREASTFEEDING
provides the foundation
for
lifelong health and
breast milk-fed infant microbiota
wellbeing
is composed by an increased
number of bifidobacteria and
lactobacilli ; formula-fed infant
microbiota has more enterococci
and enterobacteria
Gut microbiota
distribution
Immunologi
c
Nutritional
. Nutrient bioavailability
and digestion
. Production of SCFAs
. Production of essential
nutrients
e.g. vitamin B12,
vitamin K, colic acid
Key
functions
of the gut
microbiota
Physiologic
Walker
Leaky Gut
bloating, gas,
Syndrome
cramps,
food sensitivities,
aches, pains
Unsolved mystery
Intestinal
permeability
Reza Ranuh,
2016
1
6
The Important of
Intestinal Microflora Balances
Unplanned
reactions
COLI
Gastrointestinal
development
Immature digestion process
GI surface << in VLBW and
IUGR
Intrinsic immaturity of the
enteric nervous system
Food sensitive and allergies
Not properly sucking
Lactose >>
Over feeding
Transient lactase deficiency
Immune system immaturity
Microbial imbalance
Reza Ranuh,
2015
Abdominal discomfort
managements
Infantile
managemen
colic ts
Confirm :
history
Reassure
Suppor
t
Reza Ranuh,
2015
Reza Ranuh,
2015
Intestinal Microbial
Imbalance
Natural evolution of
Regurgitation in healthy
infants
Functional
constipation
Tend to be benign in
nature and self-limiting
in the majority of
infants.
Behavioural
interventions General
advice for digestive
problem
reassurance for the
parents
self-limiting condition
teaching more
appropriate responses
less overstimulation.
more appropriate
responses
Breastfeeding
Low lactose
formula
Hydrolized
formula
Paediatr Child Health Vol 16 No 1 January
2011
Zinc
The essential
Important formineral
the functioning of the
enzyme, hormone, and immune
systems.
Glutamine
Prebiotic
12
11
10
9
Bifidus
Breast-fed infants
*
8
7
6
5
4
3
2
group difference:
p<0.05
*vs. 0, # vs. 0.4
0
0.4
0.8
(n=33) (n=30) (n=27)
Lactobacillus
8
7
6
Breast-fed infants
*
5
4
3
2
1
0
group difference:
p<0.05 *vs. 0
0
0.4
0.8
(n=33) (n=30) (n=27)
Moro et al 2002
(except pAOS)
lcFOS/scGOS
the most extensively studied prebiotics
Highest number of studies
Highest number of infants involved
healthy microbiota.
Gastrointestinal Health
SelfCare
2012;3(S1):1-68
Thank You