Académique Documents
Professionnel Documents
Culture Documents
ALIMENTARY CANAL
dr. Dewi Suryani, MInfectDiS
LEARNING OBJECTIVE
Gartner, L.P, Hiatt, J.L, 2007, Colour Text Book of Histology third
edition, Saunders Elseiver, New York
Chapter 17
GENERAL PLAN OF THE ALIMENTARY
CANAL
Esophagus
Stomach
Small Intestines
Large Intestines
GENERAL PLAN OF THE
ALIMENTARY CANAL
LAYERS DESCRIPTION
STRUKTUR FUNGSI
Function Transport food mouth
stomach
T. mukosa Epithel
- Non keratinized
squamous ep.
Submucosa Esophageal gland
T. Muscularis Proximal : striated muscle
Middle: mix
Distal: smooth muscle
T. m. adventitia
Serosa/advan
titia
ESOPHAGUS AND
GASTRIC JUNCTION
transitiongland
mucous
l.p:lymphoid
fromin
stratified
ESOPHAGEAL HISTOPHYSIOLOGY
HIATAL HERNIA
Herniation of the stomach to
the thoracic
Weakens the
gastroesophageal spincter
reflux
CLINICAL CORRELATION
BARRETS ESOPHAGUS
Premalignant condition due
to gastroesphageal reflux
Part esophagus:epith
squamous simple
columnar
GASTER
GENERAL OVERVIEW
LAYER DESCRIPTION
T. Mucosa - Ep. Simple columnar
- Deep gastric pit
- lamina propria: fundus
glands
- cells of glands: Surface
lining cells, mucous neck
cells, regeneratif cells,
DNES cells, parietal cell
- MM: circular-longitudinal-
circular
T. serosa/ T. serosa
adventitia
Distribution of cell
type
Isthmus
- Surface linning cell
- DNES
Neck
- Mucous neck cell
- parietal Cell
- Regeneratif cell
- DNES
Base
-Chief Cless
- Parietal Cells
- DNES
BRANCHED,TUB.PYLO
RIC GLAND
-LONGER PITS AND
SHORTER COILED
PRODUCE:LYSOZYM
SUBMUCOSA GASTER
DENSE C.T:
LYMPHOID CELL
ACTIVATION INHIBITION
1. Cephalic 1. Stomatostatin
physiological gactor 2. Prostaglandin
(smell, sight of food, 3. Urogastrone
stress) parasimpatic
impulse n. vagus
release Ach
2. Gastric secretion:
food in the stomach
gastrin, histamin
CLINICAL SIGNFICANCE
TERMINAL FOOD
DIGESTION
NUTRIENT
ABSORPTION
ENDOCRINE
SECRETION
APPROXYMATELY 5 M
CONSIST OF:
DUODENUM
JEJENUM
ILEUM
MODIFICATION OF THE LUMINAL
SURFACE
TYPE DESCRIPTION
OF
MODIF.
Plica Tarnsverse fold of the T. mucosa and
circularis submucose
kerkringi
Villi Finger like protrusion of the lamina
propria into the lumen
Microvilli Modification of the plasmalemma of the
eipthelial cell
Crupte of Invagination of the epithelial into the
liberkuhn lamina propria
Houses various intestinal glands
INTESTINAL MUCOSE:
EPTHELIUM
DISTRIBUTION OF DIFFERENT TYPE
OF CELL
TYPE OF CELL FUNCTION
Surface absorptive tall coumnar cell
cell Acts as terminal digestion,
absorbtion water and nutrient
Goblet cell unicelular gland
produce mucus (protective
layer lining the lumen)
less in the duodenum
more towards the ileum
Enteroendocrine cell like in the stomach
Regeneratif Cell stem cell that repopulate the
epithelium
Paneth Cell produce lysozym
INTESTINAL MUCOSE:
LAMINA PROPRIA
COMPOSED OF:
-LOOSE C.T
-BLOOD AND LYMPH
VESSELS
-NERVE FIBERS
-SMOOTH MUSCLE CELLS
-AGGREGATES OF LYMPHOID
NODULES.PEYERS
PATCHES(ILEUM)
INTESINAL: SUBMUCOSA
SEROSA: MESOTHELIUM
REGIONAL DIFFERENCES
SMALL INTESTINE
MUCOUS MEMBRANE
FORMS :SERIES OF
LONGITUDINAL FOLDS.
RECTAL COLUMNS OF
MORGAGNI.
DISTAL OF THE ANAL
COVERED BY STRTIFIED
SQ.EP
L.P CONTAIN A PLEXUS OF
LARGE VEINS(EXCESSIVELY
DILATED AND
VARICOSE..HEMORRHOIDS
APPENDIX
EVAGINATION OF THE
CECUM
LUMEN:SMALL,NARROW
,IRREGULAR
ABUNDANT LYMPHOID
FOLLICLES
INTESTINAL GLANDS:FEWER
NO TENIAE COLI.