ONTOGENI COR

ABD. RAZAK DATU

DEPARTMENT OF ANATOMY
FAC. OF MEDICINE UNHAS
Terminology
Cor = Cardi = Heart
Ovutation : the release of an ovum
from the ovary
Fertilization : the fusion of an ovum
and sperm to produce an embryo
Implantation: attaching of the
fertilized ovum to the uterine wall
(endometrium)
 Age
(weeks)
1

10
Mesoderm

Paraxial mesoderm
Intermediate mesoderm
Lateral mesoderm
lamina parietal
= parietal layer
lamina viscerale
= visceral layer ( splanchnic
mesoderm layer )
 Endocardial tube
formation = heart tube
Lateral mesoderm (visceral
layer)
Angiogenetic cell cluster =
cardiogenic cord
Endocardial heart tube
Fusion of endocardial heart
tubes
 Development Endocardial
tube (heart tube)

Bulboventricular
Bulbus cordis
Ventricle (primitive)
Truncus arteriosus
Atrium
More development

Bulboventricular
Bulbus cordis
Right ventricle (ventricle
dextra)
Primitive Ventricle .
Left ventricle
(Ventricle Sinistra)
Truncus Arteriosus
Atrium
ATRIAL SEPTUM

Septum primum
Foramen primum
Foramen secundum
Septum secundum
Foramen ovale
VENTRICULAR SEPTUM

ENDOCRDIAL CUSHION
INTERVENTRICULAR FORAMEN
INTERVENTRICULAR SEPTUM
MUSCULAR PART
MEMBRANACEOUS PART
DEVELOPMNET OF
TRUNCUS ARTERIOSUS
TRUNCAL RIDGE
PULMONAL TRUNC
AORTA
Circulasi foetalis = Fetal
circulation
After birth
For. Ovale
closed Prox. part a.
vesicalis sup.
A. umbilicalis
Distal part---Medial
umbilical ligament
V. umbilicalis Lig. Teres hepatis
Lig. Venosum
Duct. venosus Arrantii
Lig. Arteriosum
Duct. arteriosus Botalli
 Basic Pathway of
CS Blood Flow
SVC Pulmonary
Right Tricuspid Right
Semilunar
Atrium Valve Ventricle
IVC Valve

Systemic Pulmonary
Capillaries Trunk

Aorta Pulmonary
Arteries

Aortic Semilunar Valve

Pulmonary
Left Capillaries
Bicuspid
Ventricle Left Atrium Pulmonary
Valve
Veins
ANOMALIES

FORAMEN OVALE PERSISTEN

PATTERN DUCTUS ARTERIOSUS
VENTRICLE SEPTAL DEFECT
Tetralogy of Fallot
DEXTRO CARDIA
ECTOPIA CORDIS
COMMON ATRIUM
TETRALOGY OF FALLOT

VENTRICULAR SEPTAL DEFECT

(VSD)
PULMONARY STENOSIS
OVERRIDING AORTAE
RIGHT VENTRICLE
HYPERTROPHY
Case 1

A male new born infant was

referred to a pediatrician
because of the blue color of his
skin (cyanosis). An ultra sound
examination was ordered to
confirm the diagnosis of
Tetralogy of Fallot
questions

In the tetralogy of Fallot there

are four cardiac abnormalities.
What are they?
Why cyanosis can be occurred ?
Case 2

a female infant was born

normally. A radiograph of the
infants chest at 3 weeks
showed generalized cardiac
enlargement. The diagnosis is
PDA.
Case 3

During an autopsy on a 72-year-

old man who had died following
chronic heart failure, it was
observed that his heart was
very large and that the
pulmonary artery and its main
branches were delated. Opening
the heart revealed a very large
Atrial Septal Defect.
Questions

1. What is ASD?
2. where would the defect likely
be located?
3. Explain why the pulmonary
artery and its branches were
delated
Question

What is PDA
Why the enlargement of the
heart can be occurred?